Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C20
  Reference Plasmid   1111525849858985_bin.8__k141_716830
  Reference Plasmid Size   2537
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051490 MGDOKNAM_00001 1086 3 Skin 1.00 protein_coding synonymous_variant LOW 156G>A Gly52Gly
M0051491 MGDOKNAM_00001 1170 3 Skin 1.00 protein_coding synonymous_variant LOW 72G>A Lys24Lys
M0051492 MGDOKNAM_00001 1194 3 Skin 1.00 protein_coding synonymous_variant LOW 48G>C Thr16Thr
M0051493 MGDOKNAM_00003 1470 3 Skin 1.00 protein_coding synonymous_variant LOW 951C>T Gly317Gly
M0051494 MGDOKNAM_00003 1532 3 Skin 1.00 protein_coding synonymous_variant LOW 889C>T Leu297Leu
M0051495 MGDOKNAM_00003 1807 3 Skin 1.00 protein_coding missense_variant MODERATE 614C>G Ala205Gly
M0051496 MGDOKNAM_00003 1865 3 Skin 1.00 protein_coding synonymous_variant LOW 556C>T Leu186Leu
M0051497 MGDOKNAM_00003 1977 3 Skin 1.00 protein_coding synonymous_variant LOW 444T>C Ile148Ile
M0051498 MGDOKNAM_00003 1980 3 Skin 1.00 protein_coding synonymous_variant LOW 441G>A Glu147Glu
M0051499 MGDOKNAM_00003 2157 3 Skin 1.00 protein_coding synonymous_variant LOW 264T>C Phe88Phe
M0051500 MGDOKNAM_00003 2194 3 Skin 1.00 protein_coding missense_variant MODERATE 227T>A Val76Asp
M0051501 MGDOKNAM_00003 2295 3 Skin 1.00 protein_coding synonymous_variant LOW 126G>A Leu42Leu
M0051502 MGDOKNAM_00003 2351 3 Skin 1.00 protein_coding synonymous_variant LOW 70C>T Leu24Leu
M0051503 MGDOKNAM_00003 2352 3 Skin 1.00 protein_coding synonymous_variant LOW 69A>G Arg23Arg
M0051504 MGDOKNAM_00003 2380 3 Skin 1.00 protein_coding missense_variant MODERATE 41A>G Gln14Arg
M0051505 MGDOKNAM_00001 2471 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -1230G>A None
M0130689 MGDOKNAM_00001 120 3 Oral 0.50 protein_coding synonymous_variant LOW 1122A>T Val374Val
M0130690 MGDOKNAM_00001 129 3 Oral 0.50 protein_coding synonymous_variant LOW 1113C>T Ile371Ile
M0130691 MGDOKNAM_00001 231 3 Oral 0.50 protein_coding synonymous_variant LOW 1011C>T Leu337Leu
M0130692 MGDOKNAM_00001 354 3 Oral 0.50 protein_coding synonymous_variant LOW 888C>T Asp296Asp
M0130693 MGDOKNAM_00001 888 3 Oral 0.50 protein_coding synonymous_variant LOW 354G>A Gly118Gly
M0130694 MGDOKNAM_00001 1086 4 Oral 0.67 protein_coding synonymous_variant LOW 156G>A Gly52Gly
M0130695 MGDOKNAM_00001 1170 6 Oral 1.00 protein_coding synonymous_variant LOW 72G>A Lys24Lys
M0130696 MGDOKNAM_00001 1180 3 Oral 0.50 protein_coding missense_variant MODERATE 62A>G Asn21Ser
M0130697 MGDOKNAM_00001 1194 6 Oral 1.00 protein_coding synonymous_variant LOW 48G>C Thr16Thr
M0130698 MGDOKNAM_00001 1203 6 Oral 1.00 protein_coding synonymous_variant LOW 39C>T Asn13Asn
M0130699 MGDOKNAM_00001 1224 4 Oral 0.67 protein_coding synonymous_variant LOW 18C>T Tyr6Tyr
M0130700 MGDOKNAM_00002 1369 3 Oral 0.50 protein_coding synonymous_variant LOW 63A>G Ala21Ala
M0130701 MGDOKNAM_00003 1532 6 Oral 1.00 protein_coding synonymous_variant LOW 889C>T Leu297Leu
M0130702 MGDOKNAM_00003 1548 5 Oral 0.83 protein_coding synonymous_variant LOW 873T>C Asn291Asn
M0130703 MGDOKNAM_00003 1668 3 Oral 0.50 protein_coding synonymous_variant LOW 753A>C Ala251Ala
M0130704 MGDOKNAM_00003 1692 3 Oral 0.50 protein_coding missense_variant MODERATE 729A>T Glu243Asp
M0130705 MGDOKNAM_00003 1752 4 Oral 0.67 protein_coding synonymous_variant LOW 669G>T Gly223Gly
M0130706 MGDOKNAM_00003 1764 6 Oral 1.00 protein_coding synonymous_variant LOW 657T>C Thr219Thr
M0130707 MGDOKNAM_00003 1807 3 Oral 0.50 protein_coding missense_variant MODERATE 614C>A Ala205Asp
M0130708 MGDOKNAM_00003 1865 6 Oral 1.00 protein_coding synonymous_variant LOW 556C>T Leu186Leu
M0130709 MGDOKNAM_00003 1977 6 Oral 1.00 protein_coding synonymous_variant LOW 444T>C Ile148Ile
M0130710 MGDOKNAM_00003 2025 3 Oral 0.50 protein_coding synonymous_variant LOW 396T>C Arg132Arg
M0130711 MGDOKNAM_00003 2146 5 Oral 0.83 protein_coding missense_variant MODERATE 275T>C Ile92Thr
M0130712 MGDOKNAM_00003 2175 5 Oral 0.83 protein_coding synonymous_variant LOW 246G>A Ser82Ser
M0130713 MGDOKNAM_00003 2194 5 Oral 0.83 protein_coding missense_variant MODERATE 227T>A Val76Asp
M0130714 MGDOKNAM_00003 2247 4 Oral 0.67 protein_coding synonymous_variant LOW 174C>T Asp58Asp
M0130715 MGDOKNAM_00003 2254 6 Oral 1.00 protein_coding missense_variant MODERATE 167A>G Lys56Arg
M0130716 MGDOKNAM_00003 2258 6 Oral 1.00 protein_coding missense_variant MODERATE 163G>A Ala55Thr
M0130717 MGDOKNAM_00003 2259 6 Oral 1.00 protein_coding synonymous_variant LOW 162C>T Ser54Ser
M0130718 MGDOKNAM_00003 2295 6 Oral 1.00 protein_coding synonymous_variant LOW 126G>A Leu42Leu
M0130719 MGDOKNAM_00003 2351 6 Oral 1.00 protein_coding missense_variant MODERATE 70C>A Leu24Ile
M0130720 MGDOKNAM_00003 2352 6 Oral 1.00 protein_coding synonymous_variant LOW 69A>G Arg23Arg
M0130721 MGDOKNAM_00003 2380 5 Oral 0.83 protein_coding missense_variant MODERATE 41A>G Gln14Arg
M0130722 MGDOKNAM_00001 2471 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1230G>A None
M0130723 MGDOKNAM_00001 2517 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1276T>G None
M0130724 MGDOKNAM_00001 1050 4 Oral 0.67 protein_coding synonymous_variant LOW 192G>A Leu64Leu
M0130725 MGDOKNAM_00002 1357 3 Oral 0.50 protein_coding synonymous_variant LOW 75T>C Ile25Ile
M0130726 MGDOKNAM_00002 1372 3 Oral 0.50 protein_coding synonymous_variant LOW 60A>T Thr20Thr
M0130727 MGDOKNAM_00002 1375 3 Oral 0.50 protein_coding synonymous_variant LOW 57T>C His19His
M0130728 MGDOKNAM_00002 1426 3 Oral 0.50 protein_coding synonymous_variant LOW 6C>T Asp2Asp
M0130729 MGDOKNAM_00003 1470 3 Oral 0.50 protein_coding synonymous_variant LOW 951C>T Gly317Gly
M0130730 MGDOKNAM_00003 1493 3 Oral 0.50 protein_coding missense_variant MODERATE 928G>A Ala310Thr
M0130731 MGDOKNAM_00003 1827 5 Oral 0.83 protein_coding synonymous_variant LOW 594C>A Arg198Arg
M0130732 MGDOKNAM_00003 2223 4 Oral 0.67 protein_coding synonymous_variant LOW 198A>T Val66Val
M0130733 MGDOKNAM_00003 2354 4 Oral 0.67 protein_coding synonymous_variant LOW 67C>A Arg23Arg
M0130734 MGDOKNAM_00003 2372 3 Oral 0.50 protein_coding missense_variant MODERATE 49G>A Val17Ile
M0130735 MGDOKNAM_00003 2373 3 Oral 0.50 protein_coding missense_variant MODERATE 48T>A Asp16Glu
M0130736 MGDOKNAM_00003 1677 3 Oral 0.50 protein_coding missense_variant MODERATE 744T>G Asp248Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term