Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2661
  Reference Plasmid   1111525849859453_bin.23__k141_210173
  Reference Plasmid Size   60391
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052217 OGBAHLJG_00023 27428 15 Skin 0.19 protein_coding missense_variant MODERATE 816A>C Lys272Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
OGBAHLJG_00004 Iron (Fe), Nickel (Ni) 74.9 3e-112 1 259 1.0000 1.0117 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
OGBAHLJG_00006 PHI:6984 mcpC 70.7 1.6e-187 1 515 0.9923 0.9885 primates salmonellosis methyl-accepting chemotaxis protein reduced virulence
OGBAHLJG_00007 PHI:6979 aer 80.2 1.6e-224 1 506 1.0000 1.0000 primates salmonellosis methyl-accepting chemotaxis protein reduced virulence
OGBAHLJG_00017 PHI:9996 lsrF 76.3 9.4e-129 1 291 0.9864 1.0000 birds meningitis 3-hydroxy-2,4-pentadione 5-phosphate thiolase reduced virulence
OGBAHLJG_00018 PHI:9995 lsrB 82.9 2.2e-158 4 337 0.9911 0.9824 birds meningitis autoinducer-2 ABC transporter periplasmic binding protein reduced virulence
OGBAHLJG_00019 PHI:9994 lsrD 72.4 9.9e-119 5 316 0.9455 0.9455 birds meningitis autoinducer-2 ABC transporter membrane subunit reduced virulence
OGBAHLJG_00023 PHI:9990 lsrK 78.2 1.2e-240 3 520 0.9923 0.9774 birds meningitis autoinducer-2 kinase reduced virulence
OGBAHLJG_00036 PHI:11405 dedA 88.1 1.8e-108 1 219 0.9955 0.9955 rodents pneumonia DedA family inner membrane protein reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OGBAHLJG_00011 QIU90503.1|GH2 99.5 0 1 1030 1 1
OGBAHLJG_00015 QIU90507.1|GH63 99.1 0 1 748 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
OGBAHLJG_00007 9.B.334.1.3 80.4 3.2e-225 1 506 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.334 The Archael N-terminal Transmembrane Domain Linked to a Sensor Kinase or MCP Domain (N-TM/SK/MCP) Family
OGBAHLJG_00013 2.A.3.7.4 92.2 3.7e-247 1 474 0.9896 0.9937 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
OGBAHLJG_00018 3.A.1.2.8 82.9 5e-158 4 337 0.9911 0.9766 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
OGBAHLJG_00019 3.A.1.2.8 72.4 2.2e-118 5 316 0.9455 0.9123 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
OGBAHLJG_00030 2.A.109.1.7 88.4 1.8e-157 1 319 0.9907 0.9938 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.109 The Tellurium Ion Resistance (TerC) Family
OGBAHLJG_00031 2.A.23.1.13 87.9 6.7e-197 1 413 0.9976 0.9976 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.23 The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family
OGBAHLJG_00034 2.A.1.14.2 90.5 2.6e-220 1 432 1.0000 0.9153 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
OGBAHLJG_00036 9.B.27.2.2 88.1 1.4e-108 1 219 0.9955 0.9955 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.27 The Death Effector Domain A (DedA) Family
OGBAHLJG_00040 1.E.34.2.1 87.7 2.8e-56 2 131 0.9774 0.9701 1 Channels/Pores 1.E Holins 1.E.34 The Putative Actinobacterial Holin-X (Hol-X) Family
OGBAHLJG_00044 9.B.124.1.2 72.7 7.5e-56 1 121 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.124 The DUF805 or PF05656 (DUF805) Family
OGBAHLJG_00048 2.A.42.2.4 92.6 1e-227 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
OGBAHLJG_00053 2.A.42.2.2 90.7 1.1e-226 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family