Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2662
  Reference Plasmid   1111525849859453_bin.9__k141_12002
  Reference Plasmid Size   5615
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052218 CPAFDBAB_00004 2607 7 Skin 0.33 protein_coding missense_variant MODERATE 479T>C Ile160Thr
M0052219 CPAFDBAB_00001 184 4 Skin 0.19 protein_coding missense_variant MODERATE 173T>C Leu58Ser
M0052220 CPAFDBAB_00001 270 4 Skin 0.19 protein_coding missense_variant MODERATE 259A>G Asn87Asp
M0052221 CPAFDBAB_00002 425 4 Skin 0.19 protein_coding missense_variant MODERATE 1090A>G Thr364Ala
M0052222 CPAFDBAB_00002 579 3 Skin 0.14 protein_coding synonymous_variant LOW 936G>A Gln312Gln
M0052223 CPAFDBAB_00002 692 3 Skin 0.14 protein_coding missense_variant MODERATE 823T>C Cys275Arg
M0052224 CPAFDBAB_00002 738 3 Skin 0.14 protein_coding synonymous_variant LOW 777A>C Ile259Ile
M0052225 CPAFDBAB_00002 870 4 Skin 0.19 protein_coding synonymous_variant LOW 645G>A Leu215Leu
M0052226 CPAFDBAB_00002 873 4 Skin 0.19 protein_coding synonymous_variant LOW 642C>T Tyr214Tyr
M0052227 CPAFDBAB_00002 1193 3 Skin 0.14 protein_coding synonymous_variant LOW 322C>T Leu108Leu
M0052228 CPAFDBAB_00002 1236 3 Skin 0.14 protein_coding synonymous_variant LOW 279G>T Thr93Thr
M0052229 CPAFDBAB_00002 1422 5 Skin 0.24 protein_coding synonymous_variant LOW 93T>C Ser31Ser
M0052230 CPAFDBAB_00003 2167 3 Skin 0.14 protein_coding synonymous_variant LOW 264T>C Phe88Phe
M0052231 CPAFDBAB_00003 2235 3 Skin 0.14 protein_coding synonymous_variant LOW 196T>C Leu66Leu
M0052232 CPAFDBAB_00004 2552 5 Skin 0.24 protein_coding missense_variant MODERATE 534A>T Leu178Phe
M0052233 CPAFDBAB_00004 2645 4 Skin 0.19 protein_coding synonymous_variant LOW 441G>A Leu147Leu
M0052234 CPAFDBAB_00004 2654 4 Skin 0.19 protein_coding synonymous_variant LOW 432G>A Ala144Ala
M0052235 CPAFDBAB_00005 3366 6 Skin 0.29 protein_coding synonymous_variant LOW 663C>A Gly221Gly
M0052236 CPAFDBAB_00005 3494 5 Skin 0.24 protein_coding synonymous_variant LOW 535C>T Leu179Leu
M0052237 CPAFDBAB_00005 3530 4 Skin 0.19 protein_coding synonymous_variant LOW 499T>C Leu167Leu
M0052238 CPAFDBAB_00005 3753 6 Skin 0.29 protein_coding synonymous_variant LOW 276T>C Leu92Leu
M0052239 CPAFDBAB_00005 3929 7 Skin 0.33 protein_coding missense_variant MODERATE 100T>C Ser34Pro
M0052240 CPAFDBAB_00002 4030 6 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -2516A>C None
M0052241 CPAFDBAB_00006 4272 5 Skin 0.24 protein_coding synonymous_variant LOW 564T>C Asn188Asn
M0052242 CPAFDBAB_00006 4398 4 Skin 0.19 protein_coding synonymous_variant LOW 438A>G Val146Val
M0052243 CPAFDBAB_00006 4404 4 Skin 0.19 protein_coding synonymous_variant LOW 432T>G Arg144Arg
M0052244 CPAFDBAB_00006 4420 4 Skin 0.19 protein_coding missense_variant MODERATE 416C>T Ala139Val
M0052245 CPAFDBAB_00006 4424 4 Skin 0.19 protein_coding missense_variant MODERATE 412A>G Ser138Gly
M0052246 CPAFDBAB_00006 4457 5 Skin 0.24 protein_coding missense_variant MODERATE 379T>C Phe127Leu
M0052247 CPAFDBAB_00006 4491 5 Skin 0.24 protein_coding missense_variant MODERATE 345G>A Met115Ile
M0052248 CPAFDBAB_00006 4545 6 Skin 0.29 protein_coding missense_variant MODERATE 291T>G Ser97Arg
M0052249 CPAFDBAB_00006 4651 6 Skin 0.29 protein_coding missense_variant MODERATE 185C>A Ala62Asp
M0052250 CPAFDBAB_00003 1816 3 Skin 0.14 protein_coding synonymous_variant LOW 615G>A Val205Val
M0052251 CPAFDBAB_00004 2723 3 Skin 0.14 protein_coding synonymous_variant LOW 363A>G Leu121Leu
M0052252 CPAFDBAB_00004 2969 3 Skin 0.14 protein_coding synonymous_variant LOW 117C>T Ser39Ser
M0052253 CPAFDBAB_00004 2981 3 Skin 0.14 protein_coding synonymous_variant LOW 105T>G Gly35Gly
M0052254 CPAFDBAB_00005 3543 3 Skin 0.14 protein_coding synonymous_variant LOW 486G>A Val162Val
M0052255 CPAFDBAB_00006 4580 3 Skin 0.14 protein_coding missense_variant MODERATE 256G>A Ala86Thr
M0052256 CPAFDBAB_00006 4780 3 Skin 0.14 protein_coding missense_variant MODERATE 56C>G Thr19Ser
M0052257 CPAFDBAB_00006 4794 4 Skin 0.19 protein_coding synonymous_variant LOW 42C>T Ile14Ile
M0052258 CPAFDBAB_00006 4807 3 Skin 0.14 protein_coding missense_variant MODERATE 29A>G Lys10Arg
M0052259 CPAFDBAB_00002 5170 5 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -3656C>G None
M0052260 CPAFDBAB_00002 5434 4 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -3920G>A None
M0052261 CPAFDBAB_00002 5560 4 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4046A>T None
M0052262 CPAFDBAB_00006 4729 3 Skin 0.14 protein_coding missense_variant MODERATE 107T>G Phe36Cys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
CPAFDBAB_00002 2.A.1.2.101 77.4 1.7e-165 1 390 0.9974 0.9873 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)