Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2665
  Reference Plasmid   1111525849859858_bin.28__k141_292482
  Reference Plasmid Size   51013
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052638 OPGFFIJG_00007 5996 11 Skin 0.22 protein_coding missense_variant MODERATE 261T>G Asp87Glu
M0052639 OPGFFIJG_00043 46197 3 Skin 0.06 protein_coding synonymous_variant LOW 504G>C Ala168Ala
M0052640 OPGFFIJG_00043 46887 3 Skin 0.06 protein_coding synonymous_variant LOW 1194T>C Asp398Asp
M0052641 OPGFFIJG_00044 48665 3 Skin 0.06 protein_coding synonymous_variant LOW 612T>C Gly204Gly
M0052642 OPGFFIJG_00044 48671 3 Skin 0.06 protein_coding synonymous_variant LOW 606T>C Ala202Ala
M0052643 OPGFFIJG_00019 20818 14 Skin 0.28 protein_coding missense_variant MODERATE 1148A>G Asp383Gly
M0052644 OPGFFIJG_00043 47082 3 Skin 0.06 protein_coding synonymous_variant LOW 1389A>G Gly463Gly
M0052645 OPGFFIJG_00043 47100 3 Skin 0.06 protein_coding synonymous_variant LOW 1407C>G Val469Val
M0052646 OPGFFIJG_00043 47337 3 Skin 0.06 protein_coding synonymous_variant LOW 1644A>G Arg548Arg
M0052647 OPGFFIJG_00043 47721 3 Skin 0.06 protein_coding synonymous_variant LOW 2028G>C Leu676Leu
M0052648 OPGFFIJG_00023 25503 4 Skin 0.08 protein_coding missense_variant MODERATE 802G>C Asp268His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term