Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2674
  Reference Plasmid   1111525849859858_bin.38__k141_77799
  Reference Plasmid Size   11663
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052829 BMFBFLMP_00005 6529 6 Skin 0.50 protein_coding missense_variant MODERATE 13A>G Thr5Ala
M0052830 BMFBFLMP_00004 6547 6 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1309C>T None
M0052831 BMFBFLMP_00004 6582 7 Skin 0.58 protein_coding upstream_gene_variant MODIFIER -1344T>C None
M0052832 BMFBFLMP_00004 6724 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -1486T>C None
M0052833 BMFBFLMP_00004 6833 7 Skin 0.58 protein_coding upstream_gene_variant MODIFIER -1595C>T None
M0052834 BMFBFLMP_00006 7392 6 Skin 0.50 protein_coding missense_variant MODERATE 664G>C Val222Leu
M0052835 BMFBFLMP_00006 7400 7 Skin 0.58 protein_coding missense_variant MODERATE 656C>T Ala219Val
M0052836 BMFBFLMP_00004 4796 3 Skin 0.25 protein_coding missense_variant MODERATE 443C>T Ala148Val
M0052837 BMFBFLMP_00004 5033 6 Skin 0.50 protein_coding missense_variant MODERATE 206A>G Glu69Gly
M0052838 BMFBFLMP_00004 8167 5 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -2929A>G None
M0052839 BMFBFLMP_00002 1817 3 Skin 0.25 protein_coding synonymous_variant LOW 144G>A Pro48Pro
M0052840 BMFBFLMP_00002 2435 3 Skin 0.25 protein_coding synonymous_variant LOW 762C>T Arg254Arg
M0052841 BMFBFLMP_00002 2465 3 Skin 0.25 protein_coding synonymous_variant LOW 792C>T Ser264Ser
M0052842 BMFBFLMP_00002 3098 3 Skin 0.25 protein_coding synonymous_variant LOW 1425T>C Gly475Gly
M0052843 BMFBFLMP_00003 3774 3 Skin 0.25 protein_coding synonymous_variant LOW 486C>A Gly162Gly
M0052844 BMFBFLMP_00006 7481 4 Skin 0.33 protein_coding missense_variant MODERATE 575C>T Ala192Val
M0052845 BMFBFLMP_00006 7483 4 Skin 0.33 protein_coding synonymous_variant LOW 573A>G Gln191Gln
M0052846 BMFBFLMP_00008 10178 3 Skin 0.25 protein_coding synonymous_variant LOW 228A>G Ala76Ala
M0052847 BMFBFLMP_00002 2150 3 Skin 0.25 protein_coding synonymous_variant LOW 477G>C Gly159Gly
M0052848 BMFBFLMP_00002 3182 4 Skin 0.33 protein_coding synonymous_variant LOW 1509T>A Ile503Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term