Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2677
  Reference Plasmid   1111525849859858_bin.42__k141_9969
  Reference Plasmid Size   11320
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052864 PGMHHNJK_00004 4135 4 Skin 0.57 protein_coding synonymous_variant LOW 1167T>C His389His
M0052865 PGMHHNJK_00004 4165 4 Skin 0.57 protein_coding synonymous_variant LOW 1197A>G Pro399Pro
M0052866 PGMHHNJK_00004 4186 4 Skin 0.57 protein_coding synonymous_variant LOW 1218T>C Val406Val
M0052867 PGMHHNJK_00005 5550 5 Skin 0.71 protein_coding synonymous_variant LOW 327G>A Gly109Gly
M0052868 PGMHHNJK_00007 7761 6 Skin 0.86 protein_coding missense_variant MODERATE 49A>G Ile17Val
M0052869 PGMHHNJK_00007 7763 6 Skin 0.86 protein_coding synonymous_variant LOW 51C>T Ile17Ile
M0052870 PGMHHNJK_00007 7772 6 Skin 0.86 protein_coding synonymous_variant LOW 60C>T Ala20Ala
M0052871 PGMHHNJK_00007 7775 6 Skin 0.86 protein_coding synonymous_variant LOW 63C>T Thr21Thr
M0052872 PGMHHNJK_00007 9104 4 Skin 0.57 protein_coding synonymous_variant LOW 1392C>T Gly464Gly
M0052873 PGMHHNJK_00007 9110 4 Skin 0.57 protein_coding synonymous_variant LOW 1398C>T Tyr466Tyr
M0052874 PGMHHNJK_00002 1463 3 Skin 0.43 protein_coding synonymous_variant LOW 261G>C Pro87Pro
M0052875 PGMHHNJK_00004 3138 3 Skin 0.43 protein_coding missense_variant MODERATE 170A>G His57Arg
M0052876 PGMHHNJK_00008 9523 4 Skin 0.57 protein_coding synonymous_variant LOW 291C>G Ala97Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term