Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2680
  Reference Plasmid   1111525849859956_bin.20__k141_363285
  Reference Plasmid Size   10460
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052882 DJPLAHHJ_00001 505 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -76A>T None
M0052883 DJPLAHHJ_00001 521 4 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -92C>T None
M0052884 DJPLAHHJ_00001 756 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -327A>G None
M0052885 DJPLAHHJ_00001 758 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -329C>G None
M0052886 DJPLAHHJ_00001 779 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -350A>G None
M0052887 DJPLAHHJ_00001 816 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -387T>C None
M0052888 DJPLAHHJ_00001 871 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -442C>T None
M0052889 DJPLAHHJ_00001 873 7 Skin 0.37 protein_coding upstream_gene_variant MODIFIER -444A>C None
M0052890 DJPLAHHJ_00001 876 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -447C>T None
M0052891 DJPLAHHJ_00001 927 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -498T>G None
M0052892 DJPLAHHJ_00001 987 7 Skin 0.37 protein_coding upstream_gene_variant MODIFIER -558G>A None
M0052893 DJPLAHHJ_00001 990 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -561G>C None
M0052894 DJPLAHHJ_00001 1034 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -605A>C None
M0052895 DJPLAHHJ_00001 1035 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -606A>G None
M0052896 DJPLAHHJ_00001 1040 7 Skin 0.37 protein_coding upstream_gene_variant MODIFIER -611C>A None
M0052897 DJPLAHHJ_00001 1041 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -612A>T None
M0052898 DJPLAHHJ_00001 1042 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -613C>G None
M0052899 DJPLAHHJ_00001 1121 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -692A>G None
M0052900 DJPLAHHJ_00001 1158 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -729A>G None
M0052901 DJPLAHHJ_00002 1317 5 Skin 0.26 protein_coding synonymous_variant LOW 132C>T Asp44Asp
M0052902 DJPLAHHJ_00002 1347 10 Skin 0.53 protein_coding synonymous_variant LOW 162G>A Ala54Ala
M0052903 DJPLAHHJ_00002 1683 8 Skin 0.42 protein_coding synonymous_variant LOW 498C>T Phe166Phe
M0052904 DJPLAHHJ_00001 2144 7 Skin 0.37 protein_coding upstream_gene_variant MODIFIER -1715G>T None
M0052905 DJPLAHHJ_00001 2178 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -1749C>T None
M0052906 DJPLAHHJ_00001 2187 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -1758T>C None
M0052907 DJPLAHHJ_00003 2973 13 Skin 0.68 protein_coding synonymous_variant LOW 196T>C Leu66Leu
M0052908 DJPLAHHJ_00003 3157 5 Skin 0.26 protein_coding synonymous_variant LOW 12T>C Leu4Leu
M0052909 DJPLAHHJ_00001 3184 12 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -2755T>C None
M0052910 DJPLAHHJ_00004 3407 13 Skin 0.68 protein_coding synonymous_variant LOW 630C>T Ile210Ile
M0052911 DJPLAHHJ_00004 3469 13 Skin 0.68 protein_coding synonymous_variant LOW 568T>C Leu190Leu
M0052912 DJPLAHHJ_00004 3521 4 Skin 0.21 protein_coding synonymous_variant LOW 516C>A Gly172Gly
M0052913 DJPLAHHJ_00004 3533 7 Skin 0.37 protein_coding synonymous_variant LOW 504T>C Tyr168Tyr
M0052914 DJPLAHHJ_00004 3583 12 Skin 0.63 protein_coding synonymous_variant LOW 454T>C Leu152Leu
M0052915 DJPLAHHJ_00004 3767 11 Skin 0.58 protein_coding synonymous_variant LOW 270A>G Thr90Thr
M0052916 DJPLAHHJ_00004 4026 13 Skin 0.68 protein_coding missense_variant MODERATE 11T>C Leu4Ser
M0052917 DJPLAHHJ_00001 4189 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3760A>T None
M0052918 DJPLAHHJ_00001 4202 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3773C>A None
M0052919 DJPLAHHJ_00001 4209 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3780C>T None
M0052920 DJPLAHHJ_00001 4217 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3788T>C None
M0052921 DJPLAHHJ_00001 4221 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3792C>T None
M0052922 DJPLAHHJ_00001 4240 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -3811G>T None
M0052923 DJPLAHHJ_00001 4288 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -3859G>A None
M0052924 DJPLAHHJ_00001 4338 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -3909C>T None
M0052925 DJPLAHHJ_00001 4346 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -3917A>C None
M0052926 DJPLAHHJ_00001 4389 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -3960T>C None
M0052927 DJPLAHHJ_00001 4409 9 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -3980G>A None
M0052928 DJPLAHHJ_00001 4441 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -4012G>A None
M0052929 DJPLAHHJ_00001 4459 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4030C>A None
M0052930 DJPLAHHJ_00001 4477 7 Skin 0.37 protein_coding upstream_gene_variant MODIFIER -4048G>A None
M0052931 DJPLAHHJ_00001 4495 8 Skin 0.42 protein_coding upstream_gene_variant MODIFIER -4066A>G None
M0052932 DJPLAHHJ_00005 4546 5 Skin 0.26 protein_coding synonymous_variant LOW 741A>G Leu247Leu
M0052933 DJPLAHHJ_00005 4552 8 Skin 0.42 protein_coding synonymous_variant LOW 735G>A Leu245Leu
M0052934 DJPLAHHJ_00005 4576 8 Skin 0.42 protein_coding synonymous_variant LOW 711A>G Val237Val
M0052935 DJPLAHHJ_00005 4630 8 Skin 0.42 protein_coding synonymous_variant LOW 657T>G Val219Val
M0052936 DJPLAHHJ_00005 4729 7 Skin 0.37 protein_coding synonymous_variant LOW 558T>G Arg186Arg
M0052937 DJPLAHHJ_00005 4843 6 Skin 0.32 protein_coding synonymous_variant LOW 444T>C Ala148Ala
M0052938 DJPLAHHJ_00005 4945 5 Skin 0.26 protein_coding synonymous_variant LOW 342A>G Val114Val
M0052939 DJPLAHHJ_00005 4995 6 Skin 0.32 protein_coding missense_variant MODERATE 292G>C Glu98Gln
M0052940 DJPLAHHJ_00005 5065 7 Skin 0.37 protein_coding synonymous_variant LOW 222C>T Phe74Phe
M0052941 DJPLAHHJ_00001 5359 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -4930C>T None
M0052942 DJPLAHHJ_00001 5363 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -4934T>C None
M0052943 DJPLAHHJ_00001 5410 4 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4981A>T None
M0052944 DJPLAHHJ_00003 5457 6 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -2289G>A None
M0052945 DJPLAHHJ_00003 5465 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -2297G>A None
M0052946 DJPLAHHJ_00006 5493 3 Skin 0.16 protein_coding synonymous_variant LOW 13T>C Leu5Leu
M0052947 DJPLAHHJ_00003 2599 4 Skin 0.21 protein_coding synonymous_variant LOW 570C>T Pro190Pro
M0052948 DJPLAHHJ_00003 2737 4 Skin 0.21 protein_coding synonymous_variant LOW 432C>T Ser144Ser
M0052949 DJPLAHHJ_00003 2851 4 Skin 0.21 protein_coding synonymous_variant LOW 318A>G Glu106Glu
M0052950 DJPLAHHJ_00004 3668 5 Skin 0.26 protein_coding synonymous_variant LOW 369A>G Val123Val
M0052951 DJPLAHHJ_00004 3929 3 Skin 0.16 protein_coding synonymous_variant LOW 108G>A Lys36Lys
M0052952 DJPLAHHJ_00001 4267 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -3838A>T None
M0052953 DJPLAHHJ_00001 4510 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4081T>C None
M0052954 DJPLAHHJ_00005 4522 3 Skin 0.16 protein_coding synonymous_variant LOW 765T>C Ser255Ser
M0052955 DJPLAHHJ_00005 4618 3 Skin 0.16 protein_coding synonymous_variant LOW 669T>C Gly223Gly
M0052956 DJPLAHHJ_00001 925 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -496G>A None
M0052957 DJPLAHHJ_00001 1157 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -728A>C None
M0052958 DJPLAHHJ_00001 1161 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -732A>G None
M0052959 DJPLAHHJ_00001 1168 3 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -739T>A None
M0052960 DJPLAHHJ_00002 1413 4 Skin 0.21 protein_coding synonymous_variant LOW 228A>G Leu76Leu
M0052961 DJPLAHHJ_00002 1769 3 Skin 0.16 protein_coding missense_variant MODERATE 584A>G Lys195Arg
M0052962 DJPLAHHJ_00002 2079 4 Skin 0.21 protein_coding synonymous_variant LOW 894C>T Asp298Asp
M0052963 DJPLAHHJ_00003 2470 4 Skin 0.21 protein_coding synonymous_variant LOW 699A>G Gln233Gln
M0052964 DJPLAHHJ_00004 3203 7 Skin 0.37 protein_coding synonymous_variant LOW 834C>T Asn278Asn
M0052965 DJPLAHHJ_00004 3251 6 Skin 0.32 protein_coding synonymous_variant LOW 786G>A Val262Val
M0052966 DJPLAHHJ_00004 3386 5 Skin 0.26 protein_coding synonymous_variant LOW 651T>C Ala217Ala
M0052967 DJPLAHHJ_00004 3246 3 Skin 0.16 protein_coding missense_variant MODERATE 791A>T Lys264Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term