Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2686
  Reference Plasmid   1111525849860314_bin.4__k141_20999
  Reference Plasmid Size   15523
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0052975 APBOKGBI_00004 5807 7 Skin 0.29 protein_coding synonymous_variant LOW 147G>C Leu49Leu
M0052976 APBOKGBI_00007 10740 3 Skin 0.13 protein_coding synonymous_variant LOW 1152C>T Val384Val
M0052977 APBOKGBI_00007 10746 3 Skin 0.13 protein_coding synonymous_variant LOW 1158C>T Gly386Gly
M0052978 APBOKGBI_00007 10755 3 Skin 0.13 protein_coding synonymous_variant LOW 1167C>A Gly389Gly
M0052979 APBOKGBI_00005 8751 6 Skin 0.25 protein_coding synonymous_variant LOW 1428C>T Asn476Asn
M0052980 APBOKGBI_00005 8802 9 Skin 0.38 protein_coding synonymous_variant LOW 1479C>T Pro493Pro
M0052981 APBOKGBI_00005 8820 9 Skin 0.38 protein_coding synonymous_variant LOW 1497G>T Ala499Ala
M0052982 APBOKGBI_00005 8826 9 Skin 0.38 protein_coding synonymous_variant LOW 1503G>A Gln501Gln
M0052983 APBOKGBI_00004 6818 7 Skin 0.29 protein_coding synonymous_variant LOW 1158G>T Val386Val
M0052984 APBOKGBI_00004 6851 7 Skin 0.29 protein_coding synonymous_variant LOW 1191G>T Leu397Leu
M0052985 APBOKGBI_00004 6887 7 Skin 0.29 protein_coding synonymous_variant LOW 1227C>G Ala409Ala
M0052986 APBOKGBI_00004 6936 8 Skin 0.33 protein_coding missense_variant MODERATE 1276A>G Ile426Val
M0052987 APBOKGBI_00005 6979 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -345G>A None
M0052988 APBOKGBI_00005 6982 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -342A>G None
M0052989 APBOKGBI_00005 6994 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -330T>C None
M0052990 APBOKGBI_00005 7001 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -323G>A None
M0052991 APBOKGBI_00005 7006 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -318C>A None
M0052992 APBOKGBI_00005 7009 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -315T>G None
M0052993 APBOKGBI_00005 7023 8 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -301G>A None
M0052994 APBOKGBI_00001 521 6 Skin 0.25 protein_coding synonymous_variant LOW 516C>G Thr172Thr
M0052995 APBOKGBI_00001 636 6 Skin 0.25 protein_coding missense_variant MODERATE 631T>A Ser211Thr
M0052996 APBOKGBI_00002 2034 7 Skin 0.29 protein_coding synonymous_variant LOW 384T>C Leu128Leu
M0052997 APBOKGBI_00002 2049 7 Skin 0.29 protein_coding synonymous_variant LOW 399C>T Tyr133Tyr
M0052998 APBOKGBI_00002 2052 7 Skin 0.29 protein_coding synonymous_variant LOW 402T>C Asp134Asp
M0052999 APBOKGBI_00002 2373 6 Skin 0.25 protein_coding synonymous_variant LOW 723C>G Leu241Leu
M0053000 APBOKGBI_00002 2388 6 Skin 0.25 protein_coding synonymous_variant LOW 738T>C Asp246Asp
M0053001 APBOKGBI_00002 2391 6 Skin 0.25 protein_coding synonymous_variant LOW 741C>T Arg247Arg
M0053002 APBOKGBI_00003 5396 3 Skin 0.13 protein_coding synonymous_variant LOW 996C>G Pro332Pro
M0053003 APBOKGBI_00004 5735 3 Skin 0.13 protein_coding synonymous_variant LOW 75G>A Arg25Arg
M0053004 APBOKGBI_00007 10632 3 Skin 0.13 protein_coding synonymous_variant LOW 1044G>A Leu348Leu
M0053005 APBOKGBI_00007 10665 3 Skin 0.13 protein_coding synonymous_variant LOW 1077C>T Thr359Thr
M0053006 APBOKGBI_00007 10671 3 Skin 0.13 protein_coding synonymous_variant LOW 1083G>A Glu361Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term