Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2701
  Reference Plasmid   1111525849861015_bin.23__k141_1051640
  Reference Plasmid Size   2565
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0053049 JBDMDAAI_00001 1306 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -5A>T None
M0053050 JBDMDAAI_00001 1350 4 Skin 1.00 protein_coding missense_variant MODERATE 40A>G Thr14Ala
M0053051 JBDMDAAI_00002 1849 4 Skin 1.00 protein_coding synonymous_variant LOW 480G>A Leu160Leu
M0053052 JBDMDAAI_00002 1895 4 Skin 1.00 protein_coding missense_variant MODERATE 434A>T Tyr145Phe
M0053053 JBDMDAAI_00002 1930 4 Skin 1.00 protein_coding synonymous_variant LOW 399C>T Tyr133Tyr
M0053054 JBDMDAAI_00002 1968 4 Skin 1.00 protein_coding missense_variant MODERATE 361A>G Asn121Asp
M0053055 JBDMDAAI_00002 2119 4 Skin 1.00 protein_coding synonymous_variant LOW 210A>T Gly70Gly
M0053056 JBDMDAAI_00002 2155 4 Skin 1.00 protein_coding synonymous_variant LOW 174T>C Val58Val
M0053057 JBDMDAAI_00002 2189 3 Skin 0.75 protein_coding missense_variant MODERATE 140A>G Glu47Gly
M0053058 JBDMDAAI_00001 73 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -1238G>A None
M0053059 JBDMDAAI_00001 625 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -686T>C None
M0053060 JBDMDAAI_00001 679 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -632A>C None
M0053061 JBDMDAAI_00001 682 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -629T>C None
M0053062 JBDMDAAI_00001 919 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -392G>T None
M0053063 JBDMDAAI_00002 1576 3 Skin 0.75 protein_coding synonymous_variant LOW 753T>G Pro251Pro
M0053064 JBDMDAAI_00002 1846 3 Skin 0.75 protein_coding synonymous_variant LOW 483T>C Asp161Asp
M0053065 JBDMDAAI_00002 1900 3 Skin 0.75 protein_coding synonymous_variant LOW 429T>A Pro143Pro
M0053066 JBDMDAAI_00002 1906 3 Skin 0.75 protein_coding synonymous_variant LOW 423A>T Val141Val
M0053067 JBDMDAAI_00002 2033 3 Skin 0.75 protein_coding missense_variant MODERATE 296A>G Lys99Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term