Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2702
  Reference Plasmid   1111525849861015_bin.5__k141_119227
  Reference Plasmid Size   18181
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0053068 KNCBCHFL_00006 8803 4 Skin 0.50 protein_coding synonymous_variant LOW 450A>C Ala150Ala
M0053069 KNCBCHFL_00006 8857 3 Skin 0.38 protein_coding synonymous_variant LOW 396T>C Pro132Pro
M0053070 KNCBCHFL_00006 9034 5 Skin 0.63 protein_coding synonymous_variant LOW 219T>C Leu73Leu
M0053071 KNCBCHFL_00007 9575 4 Skin 0.50 protein_coding synonymous_variant LOW 1425T>C Asp475Asp
M0053072 KNCBCHFL_00007 9596 5 Skin 0.63 protein_coding synonymous_variant LOW 1404T>C Gly468Gly
M0053073 KNCBCHFL_00007 9623 5 Skin 0.63 protein_coding synonymous_variant LOW 1377A>G Glu459Glu
M0053074 KNCBCHFL_00007 9632 5 Skin 0.63 protein_coding synonymous_variant LOW 1368C>G Arg456Arg
M0053075 KNCBCHFL_00007 10118 5 Skin 0.63 protein_coding synonymous_variant LOW 882G>A Leu294Leu
M0053076 KNCBCHFL_00007 10121 5 Skin 0.63 protein_coding synonymous_variant LOW 879A>T Ile293Ile
M0053077 KNCBCHFL_00007 10127 5 Skin 0.63 protein_coding synonymous_variant LOW 873T>C Cys291Cys
M0053078 KNCBCHFL_00007 10175 5 Skin 0.63 protein_coding synonymous_variant LOW 825G>C Val275Val
M0053079 KNCBCHFL_00007 10346 5 Skin 0.63 protein_coding synonymous_variant LOW 654C>G Leu218Leu
M0053080 KNCBCHFL_00007 10367 5 Skin 0.63 protein_coding synonymous_variant LOW 633T>C Leu211Leu
M0053081 KNCBCHFL_00007 10610 5 Skin 0.63 protein_coding synonymous_variant LOW 390C>T Ala130Ala
M0053082 KNCBCHFL_00007 10673 4 Skin 0.50 protein_coding synonymous_variant LOW 327G>C Ala109Ala
M0053083 KNCBCHFL_00007 10697 3 Skin 0.38 protein_coding synonymous_variant LOW 303C>T Asp101Asp
M0053084 KNCBCHFL_00007 10736 3 Skin 0.38 protein_coding synonymous_variant LOW 264G>A Arg88Arg
M0053085 KNCBCHFL_00009 7821 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4855T>A None
M0053086 KNCBCHFL_00009 7842 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4834T>C None
M0053087 KNCBCHFL_00009 7843 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4833A>T None
M0053088 KNCBCHFL_00009 7845 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4831C>T None
M0053089 KNCBCHFL_00009 7854 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4822A>C None
M0053090 KNCBCHFL_00009 7856 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4820A>G None
M0053091 KNCBCHFL_00009 7894 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4782G>A None
M0053092 KNCBCHFL_00009 7895 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4781T>G None
M0053093 KNCBCHFL_00009 7897 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4779A>G None
M0053094 KNCBCHFL_00009 7903 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4773G>A None
M0053095 KNCBCHFL_00009 7905 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4771A>C None
M0053096 KNCBCHFL_00009 7918 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4758A>G None
M0053097 KNCBCHFL_00006 8731 3 Skin 0.38 protein_coding synonymous_variant LOW 522A>G Gln174Gln
M0053098 KNCBCHFL_00006 8734 3 Skin 0.38 protein_coding synonymous_variant LOW 519A>G Ala173Ala
M0053099 KNCBCHFL_00008 11209 3 Skin 0.38 protein_coding synonymous_variant LOW 1248C>G Leu416Leu
M0053100 KNCBCHFL_00008 11652 3 Skin 0.38 protein_coding missense_variant MODERATE 805A>G Thr269Ala
M0053101 KNCBCHFL_00008 11674 3 Skin 0.38 protein_coding synonymous_variant LOW 783G>A Glu261Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term