Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2704
  Reference Plasmid   1111525849861015_bin.9__k141_1406239
  Reference Plasmid Size   4682
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0053172 FMJFJDKA_00001 150 3 Skin 0.43 protein_coding synonymous_variant LOW 126A>G Val42Val
M0053173 FMJFJDKA_00001 154 3 Skin 0.43 protein_coding missense_variant MODERATE 130G>A Ala44Thr
M0053174 FMJFJDKA_00002 475 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -618T>C None
M0053175 FMJFJDKA_00003 3242 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -26G>A None
M0053176 FMJFJDKA_00003 3624 3 Skin 0.43 protein_coding synonymous_variant LOW 357C>T Asp119Asp
M0053177 FMJFJDKA_00002 1692 3 Skin 0.43 protein_coding synonymous_variant LOW 600C>T Ser200Ser
M0053178 FMJFJDKA_00002 2265 3 Skin 0.43 protein_coding synonymous_variant LOW 1173T>A Thr391Thr
M0053179 FMJFJDKA_00002 2745 3 Skin 0.43 protein_coding synonymous_variant LOW 1653A>T Pro551Pro
M0053180 FMJFJDKA_00002 2931 3 Skin 0.43 protein_coding missense_variant MODERATE 1839A>C Lys613Asn
M0053181 FMJFJDKA_00002 3002 3 Skin 0.43 protein_coding missense_variant MODERATE 1910T>C Ile637Thr
M0053182 FMJFJDKA_00002 3081 3 Skin 0.43 protein_coding missense_variant MODERATE 1989G>T Glu663Asp
M0053183 FMJFJDKA_00002 3121 5 Skin 0.71 protein_coding missense_variant MODERATE 2029T>A Leu677Met






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FMJFJDKA_00002 VFG043465 PfbA 81.5 0 1 702 1.0 0.9764 Adherence cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein A experiment
FMJFJDKA_00002 VFG043465 PfbA 81.5 0 1 702 1.0 0.9764 Adherence cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein A prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FMJFJDKA_00002 BDB08613.1|GH0 99 0 1 702 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term