Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2708
  Reference Plasmid   1111525849861219_bin.16__k141_225317
  Reference Plasmid Size   5484
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0053200 BBGBKFPH_00001 328 4 Skin 0.80 protein_coding missense_variant MODERATE 136T>G Ser46Ala
M0053201 BBGBKFPH_00001 493 4 Skin 0.80 protein_coding missense_variant MODERATE 301T>C Ser101Pro
M0053202 BBGBKFPH_00001 511 4 Skin 0.80 protein_coding missense_variant MODERATE 319A>G Lys107Glu
M0053203 BBGBKFPH_00001 560 4 Skin 0.80 protein_coding missense_variant MODERATE 368T>C Leu123Ser
M0053204 BBGBKFPH_00001 581 4 Skin 0.80 protein_coding missense_variant MODERATE 389G>C Arg130Pro
M0053205 BBGBKFPH_00001 617 3 Skin 0.60 protein_coding missense_variant MODERATE 425T>C Phe142Ser
M0053206 BBGBKFPH_00002 796 3 Skin 0.60 protein_coding missense_variant MODERATE 323G>C Arg108Pro
M0053207 BBGBKFPH_00002 975 3 Skin 0.60 protein_coding synonymous_variant LOW 144T>C Pro48Pro
M0053208 BBGBKFPH_00003 1347 3 Skin 0.60 protein_coding missense_variant MODERATE 101A>G His34Arg
M0053209 BBGBKFPH_00003 1368 4 Skin 0.80 protein_coding missense_variant MODERATE 80G>A Gly27Asp
M0053210 BBGBKFPH_00002 1552 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -434G>A None
M0053211 BBGBKFPH_00002 1558 5 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -440T>G None
M0053212 BBGBKFPH_00004 1995 3 Skin 0.60 protein_coding synonymous_variant LOW 334C>T Leu112Leu
M0053213 BBGBKFPH_00004 2402 5 Skin 1.00 protein_coding synonymous_variant LOW 741T>C Thr247Thr
M0053214 BBGBKFPH_00004 2519 4 Skin 0.80 protein_coding synonymous_variant LOW 858T>C Ala286Ala
M0053215 BBGBKFPH_00004 2523 5 Skin 1.00 protein_coding missense_variant MODERATE 862A>G Thr288Ala
M0053216 BBGBKFPH_00002 2574 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -1456G>A None
M0053217 BBGBKFPH_00002 2591 5 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -1473T>C None
M0053218 BBGBKFPH_00002 2592 5 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -1474G>A None
M0053219 BBGBKFPH_00002 2623 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -1505G>A None
M0053220 BBGBKFPH_00002 2670 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -1552T>C None
M0053221 BBGBKFPH_00005 3181 5 Skin 1.00 protein_coding synonymous_variant LOW 369A>G Gly123Gly
M0053222 BBGBKFPH_00005 3238 3 Skin 0.60 protein_coding synonymous_variant LOW 426C>T Leu142Leu
M0053223 BBGBKFPH_00005 3433 3 Skin 0.60 protein_coding synonymous_variant LOW 621C>T Ala207Ala
M0053224 BBGBKFPH_00005 3478 3 Skin 0.60 protein_coding synonymous_variant LOW 666A>G Pro222Pro
M0053225 BBGBKFPH_00006 4444 3 Skin 0.60 protein_coding synonymous_variant LOW 660C>T Asn220Asn
M0053226 BBGBKFPH_00006 4753 3 Skin 0.60 protein_coding synonymous_variant LOW 969A>G Gly323Gly
M0053227 BBGBKFPH_00002 1465 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -347T>A None
M0053228 BBGBKFPH_00004 2543 3 Skin 0.60 protein_coding synonymous_variant LOW 882C>G Leu294Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BBGBKFPH_00006 QBJ21892.1|GT4 99 2.44e-286 1 384 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term