Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2715
  Reference Plasmid   1111525849861727_bin.16__k141_104351
  Reference Plasmid Size   3640
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0131347 IBBLNMHL_00002 237 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -626A>G None
M0131348 IBBLNMHL_00001 380 5 Oral 0.83 protein_coding missense_variant MODERATE 287A>G Asp96Gly
M0131349 IBBLNMHL_00001 409 3 Oral 0.50 protein_coding synonymous_variant LOW 258T>C Ile86Ile
M0131350 IBBLNMHL_00001 553 5 Oral 0.83 protein_coding synonymous_variant LOW 114T>C Gly38Gly
M0131351 IBBLNMHL_00001 729 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -63T>C None
M0131352 IBBLNMHL_00001 789 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -123T>A None
M0131353 IBBLNMHL_00001 795 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -129C>A None
M0131354 IBBLNMHL_00002 940 4 Oral 0.67 protein_coding synonymous_variant LOW 78G>T Gly26Gly
M0131355 IBBLNMHL_00002 1021 4 Oral 0.67 protein_coding synonymous_variant LOW 159T>C Gly53Gly
M0131356 IBBLNMHL_00002 1163 4 Oral 0.67 protein_coding missense_variant MODERATE 301A>G Ile101Val
M0131357 IBBLNMHL_00002 1222 5 Oral 0.83 protein_coding synonymous_variant LOW 360A>C Ile120Ile
M0131358 IBBLNMHL_00002 1306 3 Oral 0.50 protein_coding synonymous_variant LOW 444T>C Phe148Phe
M0131359 IBBLNMHL_00002 1309 3 Oral 0.50 protein_coding synonymous_variant LOW 447C>T Thr149Thr
M0131360 IBBLNMHL_00002 1312 3 Oral 0.50 protein_coding synonymous_variant LOW 450G>A Glu150Glu
M0131361 IBBLNMHL_00002 1325 5 Oral 0.83 protein_coding missense_variant MODERATE 463A>G Asn155Asp
M0131362 IBBLNMHL_00003 1470 3 Oral 0.50 protein_coding missense_variant MODERATE 103C>T Pro35Ser
M0131363 IBBLNMHL_00003 1505 6 Oral 1.00 protein_coding synonymous_variant LOW 138C>T Gly46Gly
M0131364 IBBLNMHL_00003 1538 5 Oral 0.83 protein_coding synonymous_variant LOW 171T>G Ser57Ser
M0131365 IBBLNMHL_00003 1541 5 Oral 0.83 protein_coding synonymous_variant LOW 174T>C Ser58Ser
M0131366 IBBLNMHL_00003 1547 5 Oral 0.83 protein_coding synonymous_variant LOW 180G>A Ala60Ala
M0131367 IBBLNMHL_00003 1550 5 Oral 0.83 protein_coding synonymous_variant LOW 183T>C Phe61Phe
M0131368 IBBLNMHL_00003 1637 4 Oral 0.67 protein_coding synonymous_variant LOW 270T>A Thr90Thr
M0131369 IBBLNMHL_00003 1666 6 Oral 1.00 protein_coding missense_variant MODERATE 299C>A Ala100Glu
M0131370 IBBLNMHL_00003 1692 6 Oral 1.00 protein_coding missense_variant MODERATE 325G>A Ala109Thr
M0131371 IBBLNMHL_00003 1772 5 Oral 0.83 protein_coding synonymous_variant LOW 405T>C His135His
M0131372 IBBLNMHL_00003 1811 3 Oral 0.50 protein_coding synonymous_variant LOW 444A>G Thr148Thr
M0131373 IBBLNMHL_00003 1883 6 Oral 1.00 protein_coding synonymous_variant LOW 516T>A Gly172Gly
M0131374 IBBLNMHL_00003 1955 6 Oral 1.00 protein_coding synonymous_variant LOW 588A>G Glu196Glu
M0131375 IBBLNMHL_00003 1988 5 Oral 0.83 protein_coding synonymous_variant LOW 621T>C His207His
M0131376 IBBLNMHL_00003 2005 6 Oral 1.00 protein_coding missense_variant MODERATE 638G>A Gly213Asp
M0131377 IBBLNMHL_00003 2021 6 Oral 1.00 protein_coding synonymous_variant LOW 654G>T Ala218Ala
M0131378 IBBLNMHL_00003 2033 5 Oral 0.83 protein_coding synonymous_variant LOW 666C>T Ala222Ala
M0131379 IBBLNMHL_00001 2173 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1507G>C None
M0131380 IBBLNMHL_00001 2275 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1609A>G None
M0131381 IBBLNMHL_00001 2396 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1730T>C None
M0131382 IBBLNMHL_00001 2397 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1731C>T None
M0131383 IBBLNMHL_00001 2532 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1866G>C None
M0131384 IBBLNMHL_00001 2575 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1909T>A None
M0131385 IBBLNMHL_00001 2601 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1935A>G None
M0131386 IBBLNMHL_00001 2648 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1982G>A None
M0131387 IBBLNMHL_00001 2659 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1993A>T None
M0131388 IBBLNMHL_00001 2671 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -2005C>T None
M0131389 IBBLNMHL_00001 2676 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -2010C>T None
M0131390 IBBLNMHL_00001 2687 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -2021C>T None
M0131391 IBBLNMHL_00001 2717 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2051G>A None
M0131392 IBBLNMHL_00001 2780 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2114T>C None
M0131393 IBBLNMHL_00001 2789 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2123C>T None
M0131394 IBBLNMHL_00001 2800 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -2134G>C None
M0131395 IBBLNMHL_00002 961 3 Oral 0.50 protein_coding synonymous_variant LOW 99A>G Glu33Glu
M0131396 IBBLNMHL_00002 976 3 Oral 0.50 protein_coding synonymous_variant LOW 114T>A Ile38Ile
M0131397 IBBLNMHL_00003 1628 3 Oral 0.50 protein_coding synonymous_variant LOW 261G>A Ala87Ala
M0131398 IBBLNMHL_00003 1670 3 Oral 0.50 protein_coding synonymous_variant LOW 303T>C Ala101Ala
M0131399 IBBLNMHL_00001 2184 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1518A>T None
M0131400 IBBLNMHL_00001 2843 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2177C>T None
M0131401 IBBLNMHL_00001 2846 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2180G>A None
M0131402 IBBLNMHL_00001 2858 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2192T>C None
M0131403 IBBLNMHL_00001 2870 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2204T>C None
M0131404 IBBLNMHL_00001 2879 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2213G>A None
M0131405 IBBLNMHL_00001 2891 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2225A>G None
M0131406 IBBLNMHL_00001 2910 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2244A>G None
M0131407 IBBLNMHL_00001 2913 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2247C>T None
M0131408 IBBLNMHL_00001 2919 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2253T>C None
M0131409 IBBLNMHL_00001 2931 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2265G>A None
M0131410 IBBLNMHL_00001 2933 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2267G>A None
M0131411 IBBLNMHL_00001 2942 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2276A>G None
M0131412 IBBLNMHL_00001 2951 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2285G>A None
M0131413 IBBLNMHL_00001 2995 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2329T>G None
M0131414 IBBLNMHL_00001 2996 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2330C>T None
M0131415 IBBLNMHL_00001 3003 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2337A>T None
M0131416 IBBLNMHL_00001 3015 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2349T>C None
M0131417 IBBLNMHL_00001 3038 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2372T>A None
M0131418 IBBLNMHL_00001 3059 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2393C>T None
M0131419 IBBLNMHL_00001 3076 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2410C>G None
M0131420 IBBLNMHL_00001 3090 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2424T>G None
M0131421 IBBLNMHL_00001 3122 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2456T>C None
M0131422 IBBLNMHL_00001 3155 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2489T>C None
M0131423 IBBLNMHL_00001 3156 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2490A>G None
M0131424 IBBLNMHL_00001 3212 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2546T>C None
M0131425 IBBLNMHL_00001 3233 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2567T>A None
M0131426 IBBLNMHL_00001 3283 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2617G>A None
M0131427 IBBLNMHL_00001 3284 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2618T>C None
M0131428 IBBLNMHL_00001 3326 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2660A>G None
M0131429 IBBLNMHL_00001 3371 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2705G>A None
M0131430 IBBLNMHL_00001 3395 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2729A>G None
M0131431 IBBLNMHL_00001 3427 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2761A>G None
M0131432 IBBLNMHL_00001 3442 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2776G>A None
M0131433 IBBLNMHL_00001 3449 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2783A>T None
M0131434 IBBLNMHL_00001 3467 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2801G>A None
M0131435 IBBLNMHL_00001 3470 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2804A>T None
M0131436 IBBLNMHL_00001 3502 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2836C>T None
M0131437 IBBLNMHL_00001 3509 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2843T>A None
M0131438 IBBLNMHL_00001 3521 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2855G>C None
M0131439 IBBLNMHL_00001 672 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -6C>T None
M0131440 IBBLNMHL_00003 1433 3 Oral 0.50 protein_coding synonymous_variant LOW 66G>A Pro22Pro
M0131441 IBBLNMHL_00003 1874 4 Oral 0.67 protein_coding synonymous_variant LOW 507T>A Ser169Ser
M0131442 IBBLNMHL_00003 1838 3 Oral 0.50 protein_coding synonymous_variant LOW 471T>C His157His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term