Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2719
  Reference Plasmid   1111525849861727_bin.16__k141_127691
  Reference Plasmid Size   1883
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0131699 AIKMCLLL_00001 84 8 Oral 0.80 protein_coding downstream_gene_variant MODIFIER *103C>T None
M0131700 AIKMCLLL_00001 135 9 Oral 0.90 protein_coding downstream_gene_variant MODIFIER *52C>A None
M0131701 AIKMCLLL_00001 168 8 Oral 0.80 protein_coding downstream_gene_variant MODIFIER *19T>C None
M0131702 AIKMCLLL_00001 169 9 Oral 0.90 protein_coding downstream_gene_variant MODIFIER *18C>T None
M0131703 AIKMCLLL_00001 174 6 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *13G>A None
M0131704 AIKMCLLL_00001 265 7 Oral 0.70 protein_coding synonymous_variant LOW 1050T>C Asp350Asp
M0131705 AIKMCLLL_00001 319 4 Oral 0.40 protein_coding synonymous_variant LOW 996A>G Ala332Ala
M0131706 AIKMCLLL_00001 556 5 Oral 0.50 protein_coding synonymous_variant LOW 759A>G Val253Val
M0131707 AIKMCLLL_00001 703 4 Oral 0.40 protein_coding missense_variant MODERATE 612C>A Asp204Glu
M0131708 AIKMCLLL_00001 712 8 Oral 0.80 protein_coding synonymous_variant LOW 603A>G Leu201Leu
M0131709 AIKMCLLL_00001 787 8 Oral 0.80 protein_coding missense_variant MODERATE 528A>T Leu176Phe
M0131710 AIKMCLLL_00001 961 7 Oral 0.70 protein_coding synonymous_variant LOW 354T>A Ile118Ile
M0131711 AIKMCLLL_00001 973 8 Oral 0.80 protein_coding synonymous_variant LOW 342T>C Phe114Phe
M0131712 AIKMCLLL_00001 1009 7 Oral 0.70 protein_coding synonymous_variant LOW 306G>A Thr102Thr
M0131713 AIKMCLLL_00001 1129 7 Oral 0.70 protein_coding synonymous_variant LOW 186T>C Tyr62Tyr
M0131714 AIKMCLLL_00001 1150 3 Oral 0.30 protein_coding synonymous_variant LOW 165G>A Gln55Gln
M0131715 AIKMCLLL_00002 1390 3 Oral 0.30 protein_coding synonymous_variant LOW 429A>T Val143Val
M0131716 AIKMCLLL_00002 1408 8 Oral 0.80 protein_coding synonymous_variant LOW 411T>A Ala137Ala
M0131717 AIKMCLLL_00002 1645 9 Oral 0.90 protein_coding synonymous_variant LOW 174G>T Ala58Ala
M0131718 AIKMCLLL_00002 1759 9 Oral 0.90 protein_coding missense_variant MODERATE 60T>G Asn20Lys
M0131719 AIKMCLLL_00002 1765 9 Oral 0.90 protein_coding synonymous_variant LOW 54A>G Ala18Ala
M0131720 AIKMCLLL_00001 61 7 Oral 0.70 protein_coding downstream_gene_variant MODIFIER *126G>A None
M0131721 AIKMCLLL_00001 586 5 Oral 0.50 protein_coding synonymous_variant LOW 729T>A Pro243Pro
M0131722 AIKMCLLL_00001 688 4 Oral 0.40 protein_coding synonymous_variant LOW 627A>T Ile209Ile
M0131723 AIKMCLLL_00001 793 3 Oral 0.30 protein_coding synonymous_variant LOW 522G>A Lys174Lys
M0131724 AIKMCLLL_00001 810 3 Oral 0.30 protein_coding synonymous_variant LOW 505T>C Leu169Leu
M0131725 AIKMCLLL_00001 865 4 Oral 0.40 protein_coding synonymous_variant LOW 450A>T Pro150Pro
M0131726 AIKMCLLL_00001 967 4 Oral 0.40 protein_coding synonymous_variant LOW 348A>G Ser116Ser
M0131727 AIKMCLLL_00001 1114 3 Oral 0.30 protein_coding synonymous_variant LOW 201T>C Arg67Arg
M0131728 AIKMCLLL_00001 1132 3 Oral 0.30 protein_coding synonymous_variant LOW 183T>G Thr61Thr
M0131729 AIKMCLLL_00002 1579 5 Oral 0.50 protein_coding synonymous_variant LOW 240A>G Val80Val
M0131730 AIKMCLLL_00002 1591 5 Oral 0.50 protein_coding synonymous_variant LOW 228C>A Leu76Leu
M0131731 AIKMCLLL_00002 1726 3 Oral 0.30 protein_coding synonymous_variant LOW 93T>C Ile31Ile
M0131732 AIKMCLLL_00001 1204 4 Oral 0.40 protein_coding synonymous_variant LOW 111C>T Cys37Cys
M0131733 AIKMCLLL_00001 1105 3 Oral 0.30 protein_coding synonymous_variant LOW 210C>T Leu70Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term