Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2721
  Reference Plasmid   1111525849861727_bin.16__k141_145608
  Reference Plasmid Size   4161
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0131800 KENPCDGE_00001 2270 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1007A>G None
M0131801 KENPCDGE_00003 2495 3 Oral 0.50 protein_coding synonymous_variant LOW 198C>T Gly66Gly
M0131802 KENPCDGE_00001 2939 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1676T>A None
M0131803 KENPCDGE_00001 2940 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1677G>C None
M0131804 KENPCDGE_00001 3053 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1790C>T None
M0131805 KENPCDGE_00001 3209 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1946A>G None
M0131806 KENPCDGE_00001 3221 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1958T>A None
M0131807 KENPCDGE_00001 3224 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1961G>A None
M0131808 KENPCDGE_00001 3275 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2012G>A None
M0131809 KENPCDGE_00001 3383 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2120T>A None
M0131810 KENPCDGE_00001 3389 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2126A>C None
M0131811 KENPCDGE_00001 3557 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2294A>T None
M0131812 KENPCDGE_00001 3595 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2332T>A None
M0131813 KENPCDGE_00001 3839 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2576T>C None
M0131814 KENPCDGE_00001 3914 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2651G>A None
M0131815 KENPCDGE_00001 3983 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2720A>G None
M0131816 KENPCDGE_00001 4043 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2780A>G None
M0131817 KENPCDGE_00002 286 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1226G>A None
M0131818 KENPCDGE_00002 312 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1200A>G None
M0131819 KENPCDGE_00002 318 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1194T>C None
M0131820 KENPCDGE_00001 601 3 Oral 0.50 protein_coding synonymous_variant LOW 663T>C Ser221Ser
M0131821 KENPCDGE_00001 616 4 Oral 0.67 protein_coding synonymous_variant LOW 648T>C Ser216Ser
M0131822 KENPCDGE_00001 961 3 Oral 0.50 protein_coding synonymous_variant LOW 303C>T Val101Val
M0131823 KENPCDGE_00001 963 3 Oral 0.50 protein_coding missense_variant MODERATE 301G>A Val101Ile
M0131824 KENPCDGE_00001 1087 4 Oral 0.67 protein_coding missense_variant MODERATE 177C>G Asp59Glu
M0131825 KENPCDGE_00001 1201 4 Oral 0.67 protein_coding synonymous_variant LOW 63T>A Ala21Ala
M0131826 KENPCDGE_00001 1272 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -9T>A None
M0131827 KENPCDGE_00001 1481 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -218C>T None
M0131828 KENPCDGE_00001 1485 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -222A>T None
M0131829 KENPCDGE_00001 1486 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -223T>A None
M0131830 KENPCDGE_00002 1670 4 Oral 0.67 protein_coding synonymous_variant LOW 159A>G Gln53Gln
M0131831 KENPCDGE_00002 1811 4 Oral 0.67 protein_coding synonymous_variant LOW 300A>T Pro100Pro
M0131832 KENPCDGE_00002 1878 3 Oral 0.50 protein_coding missense_variant MODERATE 367T>G Ser123Ala
M0131833 KENPCDGE_00002 1904 3 Oral 0.50 protein_coding synonymous_variant LOW 393T>C Gly131Gly
M0131834 KENPCDGE_00002 2090 3 Oral 0.50 protein_coding synonymous_variant LOW 579C>T Ile193Ile
M0131835 KENPCDGE_00001 3068 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1805C>T None
M0131836 KENPCDGE_00001 3380 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2117G>A None
M0131837 KENPCDGE_00001 3749 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2486A>G None
M0131838 KENPCDGE_00003 2615 3 Oral 0.50 protein_coding synonymous_variant LOW 318A>T Ser106Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term