Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2724
  Reference Plasmid   1111525849861727_bin.16__k141_160335
  Reference Plasmid Size   3535
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0131993 BLCEFNOF_00001 59 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -76A>T None
M0131994 BLCEFNOF_00001 68 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -67C>T None
M0131995 BLCEFNOF_00001 71 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -64T>C None
M0131996 BLCEFNOF_00001 89 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -46T>A None
M0131997 BLCEFNOF_00001 120 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -15C>T None
M0131998 BLCEFNOF_00001 130 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -5A>G None
M0131999 BLCEFNOF_00001 324 3 Oral 0.50 protein_coding missense_variant MODERATE 190G>A Val64Ile
M0132000 BLCEFNOF_00001 470 5 Oral 0.83 protein_coding synonymous_variant LOW 336A>T Ala112Ala
M0132001 BLCEFNOF_00001 506 4 Oral 0.67 protein_coding synonymous_variant LOW 372A>G Lys124Lys
M0132002 BLCEFNOF_00001 527 4 Oral 0.67 protein_coding synonymous_variant LOW 393T>C Thr131Thr
M0132003 BLCEFNOF_00001 560 5 Oral 0.83 protein_coding synonymous_variant LOW 426T>C Thr142Thr
M0132004 BLCEFNOF_00001 732 3 Oral 0.50 protein_coding missense_variant MODERATE 598G>A Val200Ile
M0132005 BLCEFNOF_00001 740 3 Oral 0.50 protein_coding synonymous_variant LOW 606T>A Pro202Pro
M0132006 BLCEFNOF_00001 953 5 Oral 0.83 protein_coding synonymous_variant LOW 819G>A Glu273Glu
M0132007 BLCEFNOF_00001 965 5 Oral 0.83 protein_coding synonymous_variant LOW 831G>A Thr277Thr
M0132008 BLCEFNOF_00001 1232 6 Oral 1.00 protein_coding synonymous_variant LOW 1098T>C Thr366Thr
M0132009 BLCEFNOF_00001 1247 6 Oral 1.00 protein_coding synonymous_variant LOW 1113A>G Val371Val
M0132010 BLCEFNOF_00001 1901 5 Oral 0.83 protein_coding synonymous_variant LOW 1767T>C Cys589Cys
M0132011 BLCEFNOF_00001 2141 6 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *117T>C None
M0132012 BLCEFNOF_00001 2340 5 Oral 0.83 protein_coding downstream_gene_variant MODIFIER *316C>A None
M0132013 BLCEFNOF_00002 2784 5 Oral 0.83 protein_coding missense_variant MODERATE 295T>C Tyr99His
M0132014 BLCEFNOF_00002 2844 3 Oral 0.50 protein_coding missense_variant MODERATE 235T>A Ser79Thr
M0132015 BLCEFNOF_00002 3051 4 Oral 0.67 protein_coding missense_variant MODERATE 28A>G Met10Val
M0132016 BLCEFNOF_00002 3346 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -268C>A None
M0132017 BLCEFNOF_00001 188 3 Oral 0.50 protein_coding synonymous_variant LOW 54C>T Asn18Asn
M0132018 BLCEFNOF_00001 1205 4 Oral 0.67 protein_coding synonymous_variant LOW 1071T>A Ser357Ser
M0132019 BLCEFNOF_00001 1283 4 Oral 0.67 protein_coding synonymous_variant LOW 1149T>C Asp383Asp
M0132020 BLCEFNOF_00001 1346 3 Oral 0.50 protein_coding synonymous_variant LOW 1212T>C Tyr404Tyr
M0132021 BLCEFNOF_00001 1670 4 Oral 0.67 protein_coding synonymous_variant LOW 1536A>T Gly512Gly
M0132022 BLCEFNOF_00001 1973 3 Oral 0.50 protein_coding synonymous_variant LOW 1839C>T Gly613Gly
M0132023 BLCEFNOF_00001 2319 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *295A>G None
M0132024 BLCEFNOF_00001 2427 5 Oral 0.83 protein_coding downstream_gene_variant MODIFIER *403T>C None
M0132025 BLCEFNOF_00001 2445 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *421T>G None
M0132026 BLCEFNOF_00002 2613 4 Oral 0.67 protein_coding missense_variant MODERATE 466G>T Val156Phe
M0132027 BLCEFNOF_00002 2802 4 Oral 0.67 protein_coding missense_variant MODERATE 277A>G Ser93Gly
M0132028 BLCEFNOF_00002 2880 5 Oral 0.83 protein_coding stop_gained HIGH 199A>T Arg67*
M0132029 BLCEFNOF_00002 2889 4 Oral 0.67 protein_coding missense_variant MODERATE 190G>A Ala64Thr
M0132030 BLCEFNOF_00002 2919 4 Oral 0.67 protein_coding missense_variant MODERATE 160G>A Ala54Thr
M0132031 BLCEFNOF_00002 2973 4 Oral 0.67 protein_coding synonymous_variant LOW 106T>C Leu36Leu
M0132032 BLCEFNOF_00003 3153 3 Oral 0.50 protein_coding synonymous_variant LOW 72A>T Ala24Ala
M0132033 BLCEFNOF_00003 3207 5 Oral 0.83 protein_coding synonymous_variant LOW 18A>G Arg6Arg
M0132034 BLCEFNOF_00002 3258 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -180T>C None
M0132035 BLCEFNOF_00001 2406 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *382C>T None
M0132036 BLCEFNOF_00001 2416 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *392G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term