Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2725
  Reference Plasmid   1111525849861727_bin.16__k141_164728
  Reference Plasmid Size   5122
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132037 MJNFHGML_00001 57 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -9C>A None
M0132038 MJNFHGML_00001 98 6 Oral 1.00 protein_coding synonymous_variant LOW 33T>A Thr11Thr
M0132039 MJNFHGML_00001 371 5 Oral 0.83 protein_coding synonymous_variant LOW 306G>T Ser102Ser
M0132040 MJNFHGML_00001 476 3 Oral 0.50 protein_coding synonymous_variant LOW 411C>T Gly137Gly
M0132041 MJNFHGML_00001 491 3 Oral 0.50 protein_coding synonymous_variant LOW 426A>T Ile142Ile
M0132042 MJNFHGML_00001 530 3 Oral 0.50 protein_coding synonymous_variant LOW 465C>T Gly155Gly
M0132043 MJNFHGML_00001 621 6 Oral 1.00 protein_coding missense_variant MODERATE 556A>G Ile186Val
M0132044 MJNFHGML_00001 746 6 Oral 1.00 protein_coding synonymous_variant LOW 681A>T Gly227Gly
M0132045 MJNFHGML_00001 833 5 Oral 0.83 protein_coding synonymous_variant LOW 768A>T Thr256Thr
M0132046 MJNFHGML_00001 836 6 Oral 1.00 protein_coding synonymous_variant LOW 771T>C Gly257Gly
M0132047 MJNFHGML_00001 956 6 Oral 1.00 protein_coding synonymous_variant LOW 891A>G Leu297Leu
M0132048 MJNFHGML_00001 1127 6 Oral 1.00 protein_coding synonymous_variant LOW 1062T>C Asn354Asn
M0132049 MJNFHGML_00001 1151 3 Oral 0.50 protein_coding synonymous_variant LOW 1086A>G Glu362Glu
M0132050 MJNFHGML_00001 1196 6 Oral 1.00 protein_coding synonymous_variant LOW 1131T>A Pro377Pro
M0132051 MJNFHGML_00001 1211 6 Oral 1.00 protein_coding synonymous_variant LOW 1146A>G Ser382Ser
M0132052 MJNFHGML_00001 1598 6 Oral 1.00 protein_coding synonymous_variant LOW 1533G>A Lys511Lys
M0132053 MJNFHGML_00001 1676 4 Oral 0.67 protein_coding synonymous_variant LOW 1611A>G Val537Val
M0132054 MJNFHGML_00001 2159 3 Oral 0.50 protein_coding synonymous_variant LOW 2094T>C Ile698Ile
M0132055 MJNFHGML_00001 2213 5 Oral 0.83 protein_coding synonymous_variant LOW 2148T>C Asp716Asp
M0132056 MJNFHGML_00001 2283 6 Oral 1.00 protein_coding stop_lost&splice_region_variant HIGH 2218T>C Ter740Glnext*?
M0132057 MJNFHGML_00002 2327 3 Oral 0.50 protein_coding synonymous_variant LOW 15C>T Val5Val
M0132058 MJNFHGML_00002 2801 4 Oral 0.67 protein_coding synonymous_variant LOW 489T>C Ile163Ile
M0132059 MJNFHGML_00002 2954 3 Oral 0.50 protein_coding synonymous_variant LOW 642C>T Asp214Asp
M0132060 MJNFHGML_00003 3110 4 Oral 0.67 protein_coding synonymous_variant LOW 48T>A Val16Val
M0132061 MJNFHGML_00003 3191 3 Oral 0.50 protein_coding synonymous_variant LOW 129G>A Lys43Lys
M0132062 MJNFHGML_00003 3245 4 Oral 0.67 protein_coding synonymous_variant LOW 183T>C Phe61Phe
M0132063 MJNFHGML_00003 3404 5 Oral 0.83 protein_coding synonymous_variant LOW 342A>C Pro114Pro
M0132064 MJNFHGML_00003 3467 4 Oral 0.67 protein_coding synonymous_variant LOW 405C>T Arg135Arg
M0132065 MJNFHGML_00003 3572 3 Oral 0.50 protein_coding synonymous_variant LOW 510T>C Ile170Ile
M0132066 MJNFHGML_00003 3611 5 Oral 0.83 protein_coding synonymous_variant LOW 549T>C Tyr183Tyr
M0132067 MJNFHGML_00001 506 4 Oral 0.67 protein_coding synonymous_variant LOW 441C>T Ile147Ile
M0132068 MJNFHGML_00001 641 3 Oral 0.50 protein_coding synonymous_variant LOW 576T>C Phe192Phe
M0132069 MJNFHGML_00001 893 4 Oral 0.67 protein_coding synonymous_variant LOW 828T>A Leu276Leu
M0132070 MJNFHGML_00001 1853 4 Oral 0.67 protein_coding synonymous_variant LOW 1788T>G Val596Val
M0132071 MJNFHGML_00002 2444 4 Oral 0.67 protein_coding synonymous_variant LOW 132T>C Asn44Asn
M0132072 MJNFHGML_00002 2468 5 Oral 0.83 protein_coding synonymous_variant LOW 156A>G Leu52Leu
M0132073 MJNFHGML_00002 2528 3 Oral 0.50 protein_coding synonymous_variant LOW 216C>T Thr72Thr
M0132074 MJNFHGML_00002 2549 5 Oral 0.83 protein_coding synonymous_variant LOW 237T>A Thr79Thr
M0132075 MJNFHGML_00003 3356 4 Oral 0.67 protein_coding synonymous_variant LOW 294A>C Thr98Thr
M0132076 MJNFHGML_00003 3659 4 Oral 0.67 protein_coding synonymous_variant LOW 597T>C Thr199Thr
M0132077 MJNFHGML_00003 3677 4 Oral 0.67 protein_coding synonymous_variant LOW 615T>C Asp205Asp
M0132078 MJNFHGML_00003 3698 4 Oral 0.67 protein_coding synonymous_variant LOW 636C>T Asp212Asp
M0132079 MJNFHGML_00003 3869 3 Oral 0.50 protein_coding synonymous_variant LOW 807A>T Pro269Pro
M0132080 MJNFHGML_00003 3902 4 Oral 0.67 protein_coding synonymous_variant LOW 840A>G Leu280Leu
M0132081 MJNFHGML_00003 3905 3 Oral 0.50 protein_coding synonymous_variant LOW 843T>C Asn281Asn
M0132082 MJNFHGML_00003 3914 3 Oral 0.50 protein_coding synonymous_variant LOW 852T>C Tyr284Tyr
M0132083 MJNFHGML_00003 4061 4 Oral 0.67 protein_coding synonymous_variant LOW 999C>T Asp333Asp
M0132084 MJNFHGML_00003 4487 4 Oral 0.67 protein_coding synonymous_variant LOW 1425T>A Ala475Ala
M0132085 MJNFHGML_00003 4574 3 Oral 0.50 protein_coding synonymous_variant LOW 1512T>C Asp504Asp
M0132086 MJNFHGML_00001 1643 3 Oral 0.50 protein_coding synonymous_variant LOW 1578C>T Gly526Gly
M0132087 MJNFHGML_00002 2570 3 Oral 0.50 protein_coding synonymous_variant LOW 258T>C Phe86Phe
M0132088 MJNFHGML_00002 2882 4 Oral 0.67 protein_coding synonymous_variant LOW 570C>T Phe190Phe
M0132089 MJNFHGML_00001 1970 3 Oral 0.50 protein_coding synonymous_variant LOW 1905T>C Asn635Asn
M0132090 MJNFHGML_00002 2480 3 Oral 0.50 protein_coding synonymous_variant LOW 168A>C Ile56Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term