Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2726
  Reference Plasmid   1111525849861727_bin.16__k141_49008
  Reference Plasmid Size   1753
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132091 OBBCIGAN_00001 1037 3 Oral 0.43 protein_coding missense_variant MODERATE 1022T>A Leu341Gln
M0132092 OBBCIGAN_00002 1174 4 Oral 0.57 protein_coding synonymous_variant LOW 126A>T Ala42Ala
M0132093 OBBCIGAN_00002 1180 3 Oral 0.43 protein_coding synonymous_variant LOW 132G>A Lys44Lys
M0132094 OBBCIGAN_00002 1351 3 Oral 0.43 protein_coding synonymous_variant LOW 303A>G Ala101Ala
M0132095 OBBCIGAN_00002 1354 4 Oral 0.57 protein_coding synonymous_variant LOW 306G>A Glu102Glu
M0132096 OBBCIGAN_00002 1357 4 Oral 0.57 protein_coding synonymous_variant LOW 309C>G Ser103Ser
M0132097 OBBCIGAN_00002 1369 4 Oral 0.57 protein_coding synonymous_variant LOW 321T>A Val107Val
M0132098 OBBCIGAN_00002 1375 4 Oral 0.57 protein_coding synonymous_variant LOW 327T>A Val109Val
M0132099 OBBCIGAN_00002 1378 3 Oral 0.43 protein_coding synonymous_variant LOW 330C>A Gly110Gly
M0132100 OBBCIGAN_00002 1396 3 Oral 0.43 protein_coding synonymous_variant LOW 348A>G Val116Val
M0132101 OBBCIGAN_00002 1410 4 Oral 0.57 protein_coding missense_variant MODERATE 362C>A Ala121Asp
M0132102 OBBCIGAN_00002 1456 3 Oral 0.43 protein_coding synonymous_variant LOW 408C>T Ile136Ile
M0132103 OBBCIGAN_00002 1501 4 Oral 0.57 protein_coding synonymous_variant LOW 453G>A Glu151Glu
M0132104 OBBCIGAN_00001 59 5 Oral 0.71 protein_coding missense_variant MODERATE 44C>T Ser15Phe
M0132105 OBBCIGAN_00001 116 5 Oral 0.71 protein_coding missense_variant MODERATE 101A>T His34Leu
M0132106 OBBCIGAN_00001 120 4 Oral 0.57 protein_coding synonymous_variant LOW 105A>T Ala35Ala
M0132107 OBBCIGAN_00001 135 4 Oral 0.57 protein_coding synonymous_variant LOW 120G>A Ser40Ser
M0132108 OBBCIGAN_00001 177 4 Oral 0.57 protein_coding synonymous_variant LOW 162G>A Gly54Gly
M0132109 OBBCIGAN_00001 237 4 Oral 0.57 protein_coding synonymous_variant LOW 222T>C Asp74Asp
M0132110 OBBCIGAN_00001 303 5 Oral 0.71 protein_coding synonymous_variant LOW 288G>A Gln96Gln
M0132111 OBBCIGAN_00001 317 4 Oral 0.57 protein_coding missense_variant MODERATE 302C>T Thr101Ile
M0132112 OBBCIGAN_00001 339 4 Oral 0.57 protein_coding synonymous_variant LOW 324C>T Ser108Ser
M0132113 OBBCIGAN_00001 612 3 Oral 0.43 protein_coding synonymous_variant LOW 597T>A Ser199Ser
M0132114 OBBCIGAN_00001 639 4 Oral 0.57 protein_coding synonymous_variant LOW 624A>G Val208Val
M0132115 OBBCIGAN_00001 789 4 Oral 0.57 protein_coding synonymous_variant LOW 774T>A Val258Val
M0132116 OBBCIGAN_00001 796 4 Oral 0.57 protein_coding missense_variant MODERATE 781A>G Ile261Val
M0132117 OBBCIGAN_00001 882 4 Oral 0.57 protein_coding synonymous_variant LOW 867A>G Gln289Gln
M0132118 OBBCIGAN_00001 886 4 Oral 0.57 protein_coding missense_variant MODERATE 871G>A Val291Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term