Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2727
  Reference Plasmid   1111525849861727_bin.16__k141_51067
  Reference Plasmid Size   3303
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132119 KMKGLMHI_00001 150 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1746T>C None
M0132120 KMKGLMHI_00001 214 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1682C>T None
M0132121 KMKGLMHI_00001 304 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1592A>T None
M0132122 KMKGLMHI_00001 313 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1583C>T None
M0132123 KMKGLMHI_00001 400 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1496T>C None
M0132124 KMKGLMHI_00001 646 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1250T>G None
M0132125 KMKGLMHI_00001 784 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *1112G>A None
M0132126 KMKGLMHI_00001 1892 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *4T>A None
M0132127 KMKGLMHI_00001 1983 3 Oral 0.60 protein_coding synonymous_variant LOW 723A>G Val241Val
M0132128 KMKGLMHI_00001 2061 3 Oral 0.60 protein_coding synonymous_variant LOW 645A>G Lys215Lys
M0132129 KMKGLMHI_00001 2298 4 Oral 0.80 protein_coding synonymous_variant LOW 408A>T Ser136Ser
M0132130 KMKGLMHI_00001 2313 3 Oral 0.60 protein_coding synonymous_variant LOW 393A>G Leu131Leu
M0132131 KMKGLMHI_00001 2500 4 Oral 0.80 protein_coding missense_variant MODERATE 206C>T Thr69Ile
M0132132 KMKGLMHI_00001 2553 4 Oral 0.80 protein_coding synonymous_variant LOW 153C>T Gly51Gly
M0132133 KMKGLMHI_00001 2643 4 Oral 0.80 protein_coding synonymous_variant LOW 63A>C Ile21Ile
M0132134 KMKGLMHI_00001 2646 4 Oral 0.80 protein_coding synonymous_variant LOW 60C>T Ser20Ser
M0132135 KMKGLMHI_00001 2692 4 Oral 0.80 protein_coding missense_variant MODERATE 14G>A Ser5Asn
M0132136 KMKGLMHI_00002 2742 3 Oral 0.60 protein_coding synonymous_variant LOW 357A>G Leu119Leu
M0132137 KMKGLMHI_00002 3000 4 Oral 0.80 protein_coding synonymous_variant LOW 99T>C Leu33Leu
M0132138 KMKGLMHI_00001 3141 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -436A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term