Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2732
  Reference Plasmid   1111525849861727_bin.16__k141_86408
  Reference Plasmid Size   4329
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132410 IJBFIAFJ_00001 45 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -92T>A None
M0132411 IJBFIAFJ_00001 46 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -91C>T None
M0132412 IJBFIAFJ_00001 173 3 Oral 0.43 protein_coding synonymous_variant LOW 37C>T Leu13Leu
M0132413 IJBFIAFJ_00001 268 3 Oral 0.43 protein_coding missense_variant MODERATE 132A>G Ile44Met
M0132414 IJBFIAFJ_00001 315 4 Oral 0.57 protein_coding missense_variant MODERATE 179C>G Thr60Ser
M0132415 IJBFIAFJ_00002 763 5 Oral 0.71 protein_coding synonymous_variant LOW 306C>T Asp102Asp
M0132416 IJBFIAFJ_00002 769 4 Oral 0.57 protein_coding synonymous_variant LOW 312T>A Thr104Thr
M0132417 IJBFIAFJ_00002 874 4 Oral 0.57 protein_coding synonymous_variant LOW 417T>C Pro139Pro
M0132418 IJBFIAFJ_00002 967 4 Oral 0.57 protein_coding synonymous_variant LOW 510C>T Asn170Asn
M0132419 IJBFIAFJ_00002 982 4 Oral 0.57 protein_coding synonymous_variant LOW 525T>A Ser175Ser
M0132420 IJBFIAFJ_00002 1018 3 Oral 0.43 protein_coding synonymous_variant LOW 561A>C Ala187Ala
M0132421 IJBFIAFJ_00002 1045 4 Oral 0.57 protein_coding synonymous_variant LOW 588T>C Ile196Ile
M0132422 IJBFIAFJ_00002 1105 4 Oral 0.57 protein_coding synonymous_variant LOW 648T>A Val216Val
M0132423 IJBFIAFJ_00002 1261 3 Oral 0.43 protein_coding synonymous_variant LOW 804T>C Phe268Phe
M0132424 IJBFIAFJ_00002 1339 3 Oral 0.43 protein_coding synonymous_variant LOW 882C>A Gly294Gly
M0132425 IJBFIAFJ_00002 1372 3 Oral 0.43 protein_coding synonymous_variant LOW 915C>A Thr305Thr
M0132426 IJBFIAFJ_00003 1804 4 Oral 0.57 protein_coding synonymous_variant LOW 291A>G Val97Val
M0132427 IJBFIAFJ_00003 1873 4 Oral 0.57 protein_coding synonymous_variant LOW 360A>C Gly120Gly
M0132428 IJBFIAFJ_00003 1879 4 Oral 0.57 protein_coding synonymous_variant LOW 366A>T Val122Val
M0132429 IJBFIAFJ_00003 1993 5 Oral 0.71 protein_coding synonymous_variant LOW 480C>A Ala160Ala
M0132430 IJBFIAFJ_00003 2008 5 Oral 0.71 protein_coding synonymous_variant LOW 495C>T Asp165Asp
M0132431 IJBFIAFJ_00003 2050 3 Oral 0.43 protein_coding synonymous_variant LOW 537A>C Ile179Ile
M0132432 IJBFIAFJ_00003 2081 5 Oral 0.71 protein_coding synonymous_variant LOW 568A>C Arg190Arg
M0132433 IJBFIAFJ_00003 2086 5 Oral 0.71 protein_coding synonymous_variant LOW 573T>A Thr191Thr
M0132434 IJBFIAFJ_00003 2104 4 Oral 0.57 protein_coding synonymous_variant LOW 591C>T Asp197Asp
M0132435 IJBFIAFJ_00003 2266 3 Oral 0.43 protein_coding synonymous_variant LOW 753G>A Lys251Lys
M0132436 IJBFIAFJ_00003 2303 3 Oral 0.43 protein_coding synonymous_variant LOW 790T>C Leu264Leu
M0132437 IJBFIAFJ_00003 2314 3 Oral 0.43 protein_coding synonymous_variant LOW 801C>T Ile267Ile
M0132438 IJBFIAFJ_00003 2317 3 Oral 0.43 protein_coding synonymous_variant LOW 804A>T Ile268Ile
M0132439 IJBFIAFJ_00003 2323 3 Oral 0.43 protein_coding synonymous_variant LOW 810T>C Asp270Asp
M0132440 IJBFIAFJ_00003 2335 3 Oral 0.43 protein_coding synonymous_variant LOW 822A>T Ile274Ile
M0132441 IJBFIAFJ_00003 2374 4 Oral 0.57 protein_coding synonymous_variant LOW 861T>A Pro287Pro
M0132442 IJBFIAFJ_00003 2543 5 Oral 0.71 protein_coding missense_variant MODERATE 1030T>G Ser344Ala
M0132443 IJBFIAFJ_00003 2638 5 Oral 0.71 protein_coding synonymous_variant LOW 1125T>C Gly375Gly
M0132444 IJBFIAFJ_00003 2674 5 Oral 0.71 protein_coding synonymous_variant LOW 1161C>T Gly387Gly
M0132445 IJBFIAFJ_00003 2881 4 Oral 0.57 protein_coding synonymous_variant LOW 1368C>A Thr456Thr
M0132446 IJBFIAFJ_00004 2953 4 Oral 0.57 protein_coding missense_variant MODERATE 28A>G Ile10Val
M0132447 IJBFIAFJ_00004 3006 3 Oral 0.43 protein_coding synonymous_variant LOW 81T>C Phe27Phe
M0132448 IJBFIAFJ_00004 3045 3 Oral 0.43 protein_coding synonymous_variant LOW 120T>A Leu40Leu
M0132449 IJBFIAFJ_00004 3105 4 Oral 0.57 protein_coding synonymous_variant LOW 180A>T Pro60Pro
M0132450 IJBFIAFJ_00004 3234 4 Oral 0.57 protein_coding synonymous_variant LOW 309T>C Thr103Thr
M0132451 IJBFIAFJ_00004 3249 4 Oral 0.57 protein_coding synonymous_variant LOW 324T>C Ser108Ser
M0132452 IJBFIAFJ_00004 3255 3 Oral 0.43 protein_coding synonymous_variant LOW 330C>T Asn110Asn
M0132453 IJBFIAFJ_00004 3636 4 Oral 0.57 protein_coding synonymous_variant LOW 711C>T Thr237Thr
M0132454 IJBFIAFJ_00001 3722 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *3313A>G None
M0132455 IJBFIAFJ_00001 3850 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *3441A>G None
M0132456 IJBFIAFJ_00001 4104 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *3695A>C None
M0132457 IJBFIAFJ_00001 4256 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *3847T>C None
M0132458 IJBFIAFJ_00003 2125 3 Oral 0.43 protein_coding synonymous_variant LOW 612A>G Ala204Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
IJBFIAFJ_00003 EFC71821.1|CE11 97.8 0 1 463 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term