Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2734
  Reference Plasmid   1111525849861727_bin.16__k141_89449
  Reference Plasmid Size   5612
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132482 OIIBAIEK_00001 39 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *933T>C None
M0132483 OIIBAIEK_00001 57 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *915A>G None
M0132484 OIIBAIEK_00001 85 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *887G>A None
M0132485 OIIBAIEK_00001 88 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *884A>G None
M0132486 OIIBAIEK_00001 102 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *870T>C None
M0132487 OIIBAIEK_00001 111 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *861G>A None
M0132488 OIIBAIEK_00001 129 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *843C>T None
M0132489 OIIBAIEK_00001 173 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *799C>T None
M0132490 OIIBAIEK_00001 234 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *738A>G None
M0132491 OIIBAIEK_00001 362 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *610G>T None
M0132492 OIIBAIEK_00001 501 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *471T>C None
M0132493 OIIBAIEK_00001 627 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *345A>T None
M0132494 OIIBAIEK_00001 629 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *343G>T None
M0132495 OIIBAIEK_00001 655 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *317G>A None
M0132496 OIIBAIEK_00001 795 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *177A>C None
M0132497 OIIBAIEK_00001 796 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *176C>T None
M0132498 OIIBAIEK_00001 876 5 Oral 0.63 protein_coding downstream_gene_variant MODIFIER *96G>T None
M0132499 OIIBAIEK_00001 961 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *11A>G None
M0132500 OIIBAIEK_00001 1212 5 Oral 0.63 protein_coding synonymous_variant LOW 210C>T Thr70Thr
M0132501 OIIBAIEK_00002 2004 3 Oral 0.38 protein_coding synonymous_variant LOW 783T>C Asp261Asp
M0132502 OIIBAIEK_00002 2110 3 Oral 0.38 protein_coding missense_variant MODERATE 677A>G Lys226Arg
M0132503 OIIBAIEK_00002 2112 3 Oral 0.38 protein_coding synonymous_variant LOW 675A>G Leu225Leu
M0132504 OIIBAIEK_00002 2114 3 Oral 0.38 protein_coding synonymous_variant LOW 673C>T Leu225Leu
M0132505 OIIBAIEK_00002 2124 3 Oral 0.38 protein_coding synonymous_variant LOW 663C>T Val221Val
M0132506 OIIBAIEK_00002 2163 3 Oral 0.38 protein_coding synonymous_variant LOW 624T>C Ile208Ile
M0132507 OIIBAIEK_00002 2343 3 Oral 0.38 protein_coding synonymous_variant LOW 444T>C Gly148Gly
M0132508 OIIBAIEK_00002 2436 5 Oral 0.63 protein_coding synonymous_variant LOW 351T>A Thr117Thr
M0132509 OIIBAIEK_00003 2853 4 Oral 0.50 protein_coding missense_variant MODERATE 1428T>G Asp476Glu
M0132510 OIIBAIEK_00003 2863 4 Oral 0.50 protein_coding missense_variant MODERATE 1418G>A Ser473Asn
M0132511 OIIBAIEK_00003 3080 3 Oral 0.38 protein_coding missense_variant MODERATE 1201G>C Val401Leu
M0132512 OIIBAIEK_00003 3090 3 Oral 0.38 protein_coding synonymous_variant LOW 1191C>T Thr397Thr
M0132513 OIIBAIEK_00003 3092 3 Oral 0.38 protein_coding missense_variant MODERATE 1189A>G Thr397Ala
M0132514 OIIBAIEK_00003 3456 4 Oral 0.50 protein_coding synonymous_variant LOW 825T>C Asp275Asp
M0132515 OIIBAIEK_00003 3495 4 Oral 0.50 protein_coding missense_variant MODERATE 786A>T Glu262Asp
M0132516 OIIBAIEK_00003 3513 3 Oral 0.38 protein_coding synonymous_variant LOW 768C>T Tyr256Tyr
M0132517 OIIBAIEK_00003 3552 5 Oral 0.63 protein_coding synonymous_variant LOW 729A>G Gln243Gln
M0132518 OIIBAIEK_00003 3636 5 Oral 0.63 protein_coding synonymous_variant LOW 645G>A Ser215Ser
M0132519 OIIBAIEK_00003 3765 5 Oral 0.63 protein_coding synonymous_variant LOW 516C>T Asp172Asp
M0132520 OIIBAIEK_00003 4062 4 Oral 0.50 protein_coding synonymous_variant LOW 219G>A Val73Val
M0132521 OIIBAIEK_00003 4254 5 Oral 0.63 protein_coding synonymous_variant LOW 27A>T Ile9Ile
M0132522 OIIBAIEK_00004 4380 6 Oral 0.75 protein_coding synonymous_variant LOW 711A>G Leu237Leu
M0132523 OIIBAIEK_00004 4497 3 Oral 0.38 protein_coding synonymous_variant LOW 594C>T His198His
M0132524 OIIBAIEK_00004 4584 6 Oral 0.75 protein_coding synonymous_variant LOW 507C>T Ile169Ile
M0132525 OIIBAIEK_00004 4680 6 Oral 0.75 protein_coding synonymous_variant LOW 411G>C Pro137Pro
M0132526 OIIBAIEK_00004 4686 6 Oral 0.75 protein_coding synonymous_variant LOW 405T>A Ile135Ile
M0132527 OIIBAIEK_00004 4764 3 Oral 0.38 protein_coding synonymous_variant LOW 327T>C Thr109Thr
M0132528 OIIBAIEK_00004 4854 3 Oral 0.38 protein_coding synonymous_variant LOW 237C>T Asp79Asp
M0132529 OIIBAIEK_00004 4857 6 Oral 0.75 protein_coding synonymous_variant LOW 234A>C Ile78Ile
M0132530 OIIBAIEK_00005 5172 4 Oral 0.50 protein_coding synonymous_variant LOW 420C>T Tyr140Tyr
M0132531 OIIBAIEK_00005 5198 5 Oral 0.63 protein_coding synonymous_variant LOW 394C>T Leu132Leu
M0132532 OIIBAIEK_00005 5244 6 Oral 0.75 protein_coding missense_variant MODERATE 348T>A Asp116Glu
M0132533 OIIBAIEK_00005 5337 4 Oral 0.50 protein_coding synonymous_variant LOW 255T>C Pro85Pro
M0132534 OIIBAIEK_00005 5371 5 Oral 0.63 protein_coding stop_gained HIGH 221T>A Leu74*
M0132535 OIIBAIEK_00005 5372 5 Oral 0.63 protein_coding synonymous_variant LOW 220T>C Leu74Leu
M0132536 OIIBAIEK_00005 5384 6 Oral 0.75 protein_coding missense_variant MODERATE 208A>G Asn70Asp
M0132537 OIIBAIEK_00005 5394 6 Oral 0.75 protein_coding synonymous_variant LOW 198A>G Lys66Lys
M0132538 OIIBAIEK_00005 5469 3 Oral 0.38 protein_coding synonymous_variant LOW 123G>A Lys41Lys
M0132539 OIIBAIEK_00005 5479 5 Oral 0.63 protein_coding missense_variant MODERATE 113G>A Arg38Lys
M0132540 OIIBAIEK_00005 5481 4 Oral 0.50 protein_coding synonymous_variant LOW 111A>T Val37Val
M0132541 OIIBAIEK_00005 5482 6 Oral 0.75 protein_coding missense_variant MODERATE 110T>C Val37Ala
M0132542 OIIBAIEK_00005 5490 3 Oral 0.38 protein_coding synonymous_variant LOW 102C>T Tyr34Tyr
M0132543 OIIBAIEK_00005 5502 5 Oral 0.63 protein_coding synonymous_variant LOW 90T>C Pro30Pro
M0132544 OIIBAIEK_00005 5514 3 Oral 0.38 protein_coding synonymous_variant LOW 78C>T Tyr26Tyr
M0132545 OIIBAIEK_00005 5538 6 Oral 0.75 protein_coding synonymous_variant LOW 54C>T Asp18Asp
M0132546 OIIBAIEK_00001 257 3 Oral 0.38 protein_coding downstream_gene_variant MODIFIER *715G>C None
M0132547 OIIBAIEK_00001 865 4 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *107A>G None
M0132548 OIIBAIEK_00001 1074 4 Oral 0.50 protein_coding synonymous_variant LOW 348T>C Gly116Gly
M0132549 OIIBAIEK_00001 1221 3 Oral 0.38 protein_coding synonymous_variant LOW 201A>T Ala67Ala
M0132550 OIIBAIEK_00002 1692 3 Oral 0.38 protein_coding synonymous_variant LOW 1095C>T Leu365Leu
M0132551 OIIBAIEK_00002 1770 3 Oral 0.38 protein_coding synonymous_variant LOW 1017T>C His339His
M0132552 OIIBAIEK_00002 1959 3 Oral 0.38 protein_coding synonymous_variant LOW 828C>T Asp276Asp
M0132553 OIIBAIEK_00002 2472 4 Oral 0.50 protein_coding synonymous_variant LOW 315G>A Lys105Lys
M0132554 OIIBAIEK_00004 4668 3 Oral 0.38 protein_coding synonymous_variant LOW 423C>T Tyr141Tyr
M0132555 OIIBAIEK_00004 4806 4 Oral 0.50 protein_coding synonymous_variant LOW 285A>T Thr95Thr
M0132556 OIIBAIEK_00004 4824 4 Oral 0.50 protein_coding synonymous_variant LOW 267G>A Lys89Lys
M0132557 OIIBAIEK_00004 4980 3 Oral 0.38 protein_coding synonymous_variant LOW 111C>T Thr37Thr
M0132558 OIIBAIEK_00004 4983 3 Oral 0.38 protein_coding synonymous_variant LOW 108A>G Thr36Thr
M0132559 OIIBAIEK_00005 5373 3 Oral 0.38 protein_coding synonymous_variant LOW 219C>T Ser73Ser
M0132560 OIIBAIEK_00005 5448 3 Oral 0.38 protein_coding synonymous_variant LOW 144A>G Lys48Lys
M0132561 OIIBAIEK_00004 4710 3 Oral 0.38 protein_coding synonymous_variant LOW 381C>T Tyr127Tyr
M0132562 OIIBAIEK_00004 4839 3 Oral 0.38 protein_coding synonymous_variant LOW 252A>G Glu84Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term