Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2736
  Reference Plasmid   1111525849861727_bin.16__k141_94235
  Reference Plasmid Size   3617
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0132617 CDKCLJND_00001 80 3 Oral 0.50 protein_coding synonymous_variant LOW 18A>T Pro6Pro
M0132618 CDKCLJND_00001 118 3 Oral 0.50 protein_coding missense_variant MODERATE 56G>C Gly19Ala
M0132619 CDKCLJND_00001 150 3 Oral 0.50 protein_coding synonymous_variant LOW 88C>T Leu30Leu
M0132620 CDKCLJND_00001 182 3 Oral 0.50 protein_coding synonymous_variant LOW 120A>G Ser40Ser
M0132621 CDKCLJND_00001 248 3 Oral 0.50 protein_coding synonymous_variant LOW 186A>G Ser62Ser
M0132622 CDKCLJND_00001 644 3 Oral 0.50 protein_coding synonymous_variant LOW 582A>G Ser194Ser
M0132623 CDKCLJND_00001 683 3 Oral 0.50 protein_coding synonymous_variant LOW 621G>A Leu207Leu
M0132624 CDKCLJND_00001 764 3 Oral 0.50 protein_coding synonymous_variant LOW 702C>T Ala234Ala
M0132625 CDKCLJND_00001 824 4 Oral 0.67 protein_coding synonymous_variant LOW 762T>C Asn254Asn
M0132626 CDKCLJND_00001 851 4 Oral 0.67 protein_coding synonymous_variant LOW 789A>G Val263Val
M0132627 CDKCLJND_00001 881 3 Oral 0.50 protein_coding synonymous_variant LOW 819A>G Gln273Gln
M0132628 CDKCLJND_00002 987 4 Oral 0.67 protein_coding missense_variant MODERATE 44G>A Gly15Asp
M0132629 CDKCLJND_00002 1078 3 Oral 0.50 protein_coding synonymous_variant LOW 135T>A Thr45Thr
M0132630 CDKCLJND_00002 1203 3 Oral 0.50 protein_coding missense_variant MODERATE 260A>G Asn87Ser
M0132631 CDKCLJND_00002 1267 4 Oral 0.67 protein_coding synonymous_variant LOW 324A>G Thr108Thr
M0132632 CDKCLJND_00002 1291 4 Oral 0.67 protein_coding synonymous_variant LOW 348A>C Gly116Gly
M0132633 CDKCLJND_00002 1336 4 Oral 0.67 protein_coding synonymous_variant LOW 393C>T Asp131Asp
M0132634 CDKCLJND_00002 1462 3 Oral 0.50 protein_coding synonymous_variant LOW 519C>T Thr173Thr
M0132635 CDKCLJND_00002 1465 3 Oral 0.50 protein_coding synonymous_variant LOW 522A>G Thr174Thr
M0132636 CDKCLJND_00002 1516 4 Oral 0.67 protein_coding synonymous_variant LOW 573C>T Arg191Arg
M0132637 CDKCLJND_00002 1568 3 Oral 0.50 protein_coding missense_variant MODERATE 625A>G Ile209Val
M0132638 CDKCLJND_00002 1573 3 Oral 0.50 protein_coding synonymous_variant LOW 630T>G Val210Val
M0132639 CDKCLJND_00002 1609 4 Oral 0.67 protein_coding synonymous_variant LOW 666C>T Asn222Asn
M0132640 CDKCLJND_00002 1648 4 Oral 0.67 protein_coding synonymous_variant LOW 705C>T Cys235Cys
M0132641 CDKCLJND_00002 1660 4 Oral 0.67 protein_coding synonymous_variant LOW 717C>T Gly239Gly
M0132642 CDKCLJND_00002 1663 4 Oral 0.67 protein_coding synonymous_variant LOW 720T>C Cys240Cys
M0132643 CDKCLJND_00002 1705 3 Oral 0.50 protein_coding synonymous_variant LOW 762T>C Asn254Asn
M0132644 CDKCLJND_00001 1746 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *799C>T None
M0132645 CDKCLJND_00001 1752 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *805A>G None
M0132646 CDKCLJND_00001 1769 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *822A>G None
M0132647 CDKCLJND_00001 1786 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *839A>G None
M0132648 CDKCLJND_00001 1788 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *841A>C None
M0132649 CDKCLJND_00003 2675 4 Oral 0.67 protein_coding synonymous_variant LOW 531A>T Ile177Ile
M0132650 CDKCLJND_00003 2762 3 Oral 0.50 protein_coding synonymous_variant LOW 444C>T Arg148Arg
M0132651 CDKCLJND_00003 2555 3 Oral 0.50 protein_coding synonymous_variant LOW 651T>C Gly217Gly
M0132652 CDKCLJND_00003 2884 4 Oral 0.67 protein_coding missense_variant MODERATE 322G>C Gly108Arg
M0132653 CDKCLJND_00003 2897 4 Oral 0.67 protein_coding synonymous_variant LOW 309T>A Gly103Gly
M0132654 CDKCLJND_00003 2912 4 Oral 0.67 protein_coding synonymous_variant LOW 294C>T Val98Val
M0132655 CDKCLJND_00003 2981 4 Oral 0.67 protein_coding synonymous_variant LOW 225A>G Gln75Gln
M0132656 CDKCLJND_00003 3262 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -57G>A None
M0132657 CDKCLJND_00003 3263 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -58T>C None
M0132658 CDKCLJND_00003 3298 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -93A>G None
M0132659 CDKCLJND_00003 3317 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -112T>C None
M0132660 CDKCLJND_00003 3398 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -193T>C None
M0132661 CDKCLJND_00003 3408 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -203A>C None
M0132662 CDKCLJND_00003 3417 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -212A>T None
M0132663 CDKCLJND_00003 3483 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -278T>G None
M0132664 CDKCLJND_00003 3494 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -289T>C None
M0132665 CDKCLJND_00003 3318 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -113C>T None
M0132666 CDKCLJND_00003 3355 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -150A>G None
M0132667 CDKCLJND_00003 3423 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -218A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CDKCLJND_00002 EFC71026.1|GT2 95.7 1.5e-178 1 258 1 1
CDKCLJND_00003 EFC71027.1|CBM50 95.9 7.35e-219 1 315 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term