Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2738
  Reference Plasmid   1111525849861727_bin.5__k141_49577
  Reference Plasmid Size   3102
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0053268 FAFCPMNL_00001 1423 3 Skin 0.75 protein_coding synonymous_variant LOW 1071C>T Asn357Asn
M0053269 FAFCPMNL_00001 1448 3 Skin 0.75 protein_coding missense_variant MODERATE 1046C>T Ala349Val
M0053270 FAFCPMNL_00001 1453 3 Skin 0.75 protein_coding synonymous_variant LOW 1041T>C Ala347Ala
M0053271 FAFCPMNL_00001 1561 3 Skin 0.75 protein_coding synonymous_variant LOW 933T>C Asn311Asn
M0053272 FAFCPMNL_00001 1570 3 Skin 0.75 protein_coding synonymous_variant LOW 924T>C Arg308Arg
M0053273 FAFCPMNL_00001 1636 3 Skin 0.75 protein_coding synonymous_variant LOW 858G>T Ala286Ala
M0053274 FAFCPMNL_00001 1660 3 Skin 0.75 protein_coding synonymous_variant LOW 834G>A Gly278Gly
M0053275 FAFCPMNL_00001 1812 3 Skin 0.75 protein_coding missense_variant MODERATE 682G>A Asp228Asn
M0053276 FAFCPMNL_00001 1819 3 Skin 0.75 protein_coding synonymous_variant LOW 675T>C Ser225Ser
M0053277 FAFCPMNL_00001 1846 3 Skin 0.75 protein_coding synonymous_variant LOW 648T>C Ser216Ser
M0053278 FAFCPMNL_00001 208 3 Skin 0.75 protein_coding synonymous_variant LOW 2286G>T Thr762Thr
M0053279 FAFCPMNL_00001 262 3 Skin 0.75 protein_coding synonymous_variant LOW 2232A>G Gly744Gly
M0053280 FAFCPMNL_00001 268 3 Skin 0.75 protein_coding synonymous_variant LOW 2226T>C Leu742Leu
M0053281 FAFCPMNL_00001 300 3 Skin 0.75 protein_coding missense_variant MODERATE 2194A>G Ile732Val
M0053282 FAFCPMNL_00001 367 3 Skin 0.75 protein_coding synonymous_variant LOW 2127A>C Arg709Arg
M0053283 FAFCPMNL_00001 393 3 Skin 0.75 protein_coding missense_variant MODERATE 2101A>G Ile701Val
M0053284 FAFCPMNL_00001 540 3 Skin 0.75 protein_coding missense_variant MODERATE 1954G>T Ala652Ser
M0053285 FAFCPMNL_00001 628 3 Skin 0.75 protein_coding synonymous_variant LOW 1866G>C Thr622Thr
M0053286 FAFCPMNL_00001 679 3 Skin 0.75 protein_coding synonymous_variant LOW 1815T>A Gly605Gly
M0053287 FAFCPMNL_00001 736 3 Skin 0.75 protein_coding synonymous_variant LOW 1758C>T Asp586Asp
M0053288 FAFCPMNL_00001 768 3 Skin 0.75 protein_coding missense_variant MODERATE 1726A>C Ile576Leu
M0053289 FAFCPMNL_00001 961 3 Skin 0.75 protein_coding synonymous_variant LOW 1533T>C Ser511Ser
M0053290 FAFCPMNL_00001 1002 3 Skin 0.75 protein_coding missense_variant MODERATE 1492G>T Ala498Ser
M0053291 FAFCPMNL_00001 1051 3 Skin 0.75 protein_coding missense_variant MODERATE 1443C>A Asp481Glu
M0053292 FAFCPMNL_00001 1072 3 Skin 0.75 protein_coding synonymous_variant LOW 1422C>T Gly474Gly
M0053293 FAFCPMNL_00001 1114 3 Skin 0.75 protein_coding synonymous_variant LOW 1380A>G Leu460Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term