Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2742
  Reference Plasmid   1111525849861839_bin.8__k141_38402
  Reference Plasmid Size   76767
  Reference Plasmid GC Content   0.53
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0054159 HDNNILPG_00002 1743 4 Skin 0.57 protein_coding synonymous_variant LOW 1329T>C Gly443Gly
M0054160 HDNNILPG_00002 1770 4 Skin 0.57 protein_coding synonymous_variant LOW 1302A>G Ser434Ser
M0054161 HDNNILPG_00002 1773 4 Skin 0.57 protein_coding synonymous_variant LOW 1299G>C Pro433Pro
M0054162 HDNNILPG_00002 1794 4 Skin 0.57 protein_coding synonymous_variant LOW 1278C>T Asp426Asp
M0054163 HDNNILPG_00002 1811 4 Skin 0.57 protein_coding synonymous_variant LOW 1261T>C Leu421Leu
M0054164 HDNNILPG_00002 1815 4 Skin 0.57 protein_coding synonymous_variant LOW 1257A>G Glu419Glu
M0054165 HDNNILPG_00002 1818 4 Skin 0.57 protein_coding synonymous_variant LOW 1254T>C Ala418Ala
M0054166 HDNNILPG_00002 1821 4 Skin 0.57 protein_coding synonymous_variant LOW 1251T>C Ala417Ala
M0054167 HDNNILPG_00002 1857 4 Skin 0.57 protein_coding synonymous_variant LOW 1215C>T Ile405Ile
M0054168 HDNNILPG_00002 1863 4 Skin 0.57 protein_coding synonymous_variant LOW 1209A>G Glu403Glu
M0054169 HDNNILPG_00002 1899 4 Skin 0.57 protein_coding synonymous_variant LOW 1173A>G Gly391Gly
M0054170 HDNNILPG_00002 1917 4 Skin 0.57 protein_coding synonymous_variant LOW 1155C>T Ile385Ile
M0054171 HDNNILPG_00002 1938 4 Skin 0.57 protein_coding synonymous_variant LOW 1134T>C Ser378Ser
M0054172 HDNNILPG_00002 2016 3 Skin 0.43 protein_coding synonymous_variant LOW 1056G>A Glu352Glu
M0054173 HDNNILPG_00002 2082 3 Skin 0.43 protein_coding synonymous_variant LOW 990A>G Gln330Gln
M0054174 HDNNILPG_00002 2094 4 Skin 0.57 protein_coding synonymous_variant LOW 978A>G Leu326Leu
M0054175 HDNNILPG_00002 2096 4 Skin 0.57 protein_coding synonymous_variant LOW 976T>C Leu326Leu
M0054176 HDNNILPG_00002 2118 3 Skin 0.43 protein_coding synonymous_variant LOW 954C>T Leu318Leu
M0054177 HDNNILPG_00002 2126 4 Skin 0.57 protein_coding synonymous_variant LOW 946T>C Leu316Leu
M0054178 HDNNILPG_00002 2157 4 Skin 0.57 protein_coding synonymous_variant LOW 915T>C Phe305Phe
M0054179 HDNNILPG_00002 2211 4 Skin 0.57 protein_coding synonymous_variant LOW 861A>G Gln287Gln
M0054180 HDNNILPG_00002 2217 4 Skin 0.57 protein_coding synonymous_variant LOW 855G>A Leu285Leu
M0054181 HDNNILPG_00002 2238 4 Skin 0.57 protein_coding synonymous_variant LOW 834G>C Val278Val
M0054182 HDNNILPG_00002 2286 4 Skin 0.57 protein_coding synonymous_variant LOW 786C>T Phe262Phe
M0054183 HDNNILPG_00002 2289 4 Skin 0.57 protein_coding synonymous_variant LOW 783T>C Asn261Asn
M0054184 HDNNILPG_00002 2292 4 Skin 0.57 protein_coding synonymous_variant LOW 780T>G Ser260Ser
M0054185 HDNNILPG_00002 2301 3 Skin 0.43 protein_coding synonymous_variant LOW 771C>T Thr257Thr
M0054186 HDNNILPG_00002 2319 4 Skin 0.57 protein_coding synonymous_variant LOW 753G>C Arg251Arg
M0054187 HDNNILPG_00002 2364 3 Skin 0.43 protein_coding synonymous_variant LOW 708C>T Ile236Ile
M0054188 HDNNILPG_00002 2379 3 Skin 0.43 protein_coding synonymous_variant LOW 693A>G Pro231Pro
M0054189 HDNNILPG_00002 2391 3 Skin 0.43 protein_coding synonymous_variant LOW 681A>G Val227Val
M0054190 HDNNILPG_00002 2436 3 Skin 0.43 protein_coding synonymous_variant LOW 636G>A Gln212Gln
M0054191 HDNNILPG_00002 2466 3 Skin 0.43 protein_coding synonymous_variant LOW 606G>A Val202Val
M0054192 HDNNILPG_00002 2492 4 Skin 0.57 protein_coding synonymous_variant LOW 580T>C Leu194Leu
M0054193 HDNNILPG_00002 2571 3 Skin 0.43 protein_coding synonymous_variant LOW 501T>C Ala167Ala
M0054194 HDNNILPG_00002 2598 3 Skin 0.43 protein_coding synonymous_variant LOW 474T>C Gly158Gly
M0054195 HDNNILPG_00002 2601 4 Skin 0.57 protein_coding synonymous_variant LOW 471C>T Asp157Asp
M0054196 HDNNILPG_00002 2604 3 Skin 0.43 protein_coding synonymous_variant LOW 468G>A Ser156Ser
M0054197 HDNNILPG_00002 2606 4 Skin 0.57 protein_coding missense_variant MODERATE 466T>G Ser156Ala
M0054198 HDNNILPG_00002 2616 4 Skin 0.57 protein_coding synonymous_variant LOW 456C>G Leu152Leu
M0054199 HDNNILPG_00002 2646 3 Skin 0.43 protein_coding synonymous_variant LOW 426C>T Thr142Thr
M0054200 HDNNILPG_00002 2694 3 Skin 0.43 protein_coding synonymous_variant LOW 378T>C Thr126Thr
M0054201 HDNNILPG_00002 2955 4 Skin 0.57 protein_coding synonymous_variant LOW 117T>C His39His
M0054202 HDNNILPG_00003 3258 4 Skin 0.57 protein_coding synonymous_variant LOW 487C>T Leu163Leu
M0054203 HDNNILPG_00003 3274 4 Skin 0.57 protein_coding synonymous_variant LOW 471T>C Thr157Thr
M0054204 HDNNILPG_00003 3277 4 Skin 0.57 protein_coding synonymous_variant LOW 468C>T Phe156Phe
M0054205 HDNNILPG_00003 3280 4 Skin 0.57 protein_coding synonymous_variant LOW 465A>G Glu155Glu
M0054206 HDNNILPG_00003 3286 4 Skin 0.57 protein_coding synonymous_variant LOW 459T>C Ser153Ser
M0054207 HDNNILPG_00003 3313 3 Skin 0.43 protein_coding synonymous_variant LOW 432C>T Arg144Arg
M0054208 HDNNILPG_00003 3317 4 Skin 0.57 protein_coding missense_variant MODERATE 428T>C Met143Thr
M0054209 HDNNILPG_00003 3388 4 Skin 0.57 protein_coding synonymous_variant LOW 357A>G Gly119Gly
M0054210 HDNNILPG_00003 3439 4 Skin 0.57 protein_coding synonymous_variant LOW 306T>C Pro102Pro
M0054211 HDNNILPG_00003 3574 4 Skin 0.57 protein_coding synonymous_variant LOW 171T>C Val57Val
M0054212 HDNNILPG_00003 3592 3 Skin 0.43 protein_coding synonymous_variant LOW 153C>T Asp51Asp
M0054213 HDNNILPG_00002 3748 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -677C>A None
M0054214 HDNNILPG_00004 3913 3 Skin 0.43 protein_coding synonymous_variant LOW 105C>T Cys35Cys
M0054215 HDNNILPG_00004 3916 3 Skin 0.43 protein_coding synonymous_variant LOW 108T>C Arg36Arg
M0054216 HDNNILPG_00004 3929 3 Skin 0.43 protein_coding stop_lost&splice_region_variant HIGH 121T>A Ter41Lysext*?
M0054217 HDNNILPG_00005 3939 3 Skin 0.43 protein_coding missense_variant MODERATE 22T>A Ser8Thr
M0054218 HDNNILPG_00005 3972 3 Skin 0.43 protein_coding synonymous_variant LOW 55C>T Leu19Leu
M0054219 HDNNILPG_00005 3992 3 Skin 0.43 protein_coding synonymous_variant LOW 75T>C Tyr25Tyr
M0054220 HDNNILPG_00005 4002 3 Skin 0.43 protein_coding missense_variant MODERATE 85A>G Thr29Ala
M0054221 HDNNILPG_00005 4013 3 Skin 0.43 protein_coding synonymous_variant LOW 96G>A Val32Val
M0054222 HDNNILPG_00005 4052 3 Skin 0.43 protein_coding synonymous_variant LOW 135T>C Thr45Thr
M0054223 HDNNILPG_00005 4058 3 Skin 0.43 protein_coding synonymous_variant LOW 141A>G Thr47Thr
M0054224 HDNNILPG_00005 4073 4 Skin 0.57 protein_coding synonymous_variant LOW 156A>G Glu52Glu
M0054225 HDNNILPG_00005 4079 4 Skin 0.57 protein_coding synonymous_variant LOW 162C>T Gly54Gly
M0054226 HDNNILPG_00005 4103 3 Skin 0.43 protein_coding synonymous_variant LOW 186A>G Pro62Pro
M0054227 HDNNILPG_00005 4142 3 Skin 0.43 protein_coding synonymous_variant LOW 225T>C Asn75Asn
M0054228 HDNNILPG_00005 4178 4 Skin 0.57 protein_coding synonymous_variant LOW 261G>A Glu87Glu
M0054229 HDNNILPG_00005 4199 4 Skin 0.57 protein_coding synonymous_variant LOW 282C>G Val94Val
M0054230 HDNNILPG_00005 4298 4 Skin 0.57 protein_coding synonymous_variant LOW 381T>C Ala127Ala
M0054231 HDNNILPG_00005 4364 3 Skin 0.43 protein_coding synonymous_variant LOW 447A>G Arg149Arg
M0054232 HDNNILPG_00005 4460 4 Skin 0.57 protein_coding synonymous_variant LOW 543A>G Ala181Ala
M0054233 HDNNILPG_00005 4469 3 Skin 0.43 protein_coding synonymous_variant LOW 552G>A Leu184Leu
M0054234 HDNNILPG_00005 4490 3 Skin 0.43 protein_coding synonymous_variant LOW 573A>G Leu191Leu
M0054235 HDNNILPG_00005 4520 4 Skin 0.57 protein_coding synonymous_variant LOW 603C>T Val201Val
M0054236 HDNNILPG_00005 4697 4 Skin 0.57 protein_coding synonymous_variant LOW 780T>C Ser260Ser
M0054237 HDNNILPG_00005 4791 4 Skin 0.57 protein_coding synonymous_variant LOW 874T>C Leu292Leu
M0054238 HDNNILPG_00005 5103 4 Skin 0.57 protein_coding missense_variant MODERATE 1186G>C Glu396Gln
M0054239 HDNNILPG_00005 5210 3 Skin 0.43 protein_coding synonymous_variant LOW 1293C>T Phe431Phe
M0054240 HDNNILPG_00005 5255 4 Skin 0.57 protein_coding synonymous_variant LOW 1338T>G Ala446Ala
M0054241 HDNNILPG_00006 5462 3 Skin 0.43 protein_coding missense_variant MODERATE 142A>G Ile48Val
M0054242 HDNNILPG_00006 5487 4 Skin 0.57 protein_coding missense_variant MODERATE 167A>G Asn56Ser
M0054243 HDNNILPG_00006 5488 3 Skin 0.43 protein_coding synonymous_variant LOW 168T>C Asn56Asn
M0054244 HDNNILPG_00006 5512 4 Skin 0.57 protein_coding missense_variant MODERATE 192A>C Glu64Asp
M0054245 HDNNILPG_00006 5572 4 Skin 0.57 protein_coding synonymous_variant LOW 252A>G Thr84Thr
M0054246 HDNNILPG_00006 5591 3 Skin 0.43 protein_coding missense_variant MODERATE 271A>G Asn91Asp
M0054247 HDNNILPG_00006 5593 3 Skin 0.43 protein_coding synonymous_variant LOW 273C>T Asn91Asn
M0054248 HDNNILPG_00002 5683 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2612C>G None
M0054249 HDNNILPG_00007 5760 3 Skin 0.43 protein_coding synonymous_variant LOW 51A>G Val17Val
M0054250 HDNNILPG_00007 5886 4 Skin 0.57 protein_coding synonymous_variant LOW 177C>T Phe59Phe
M0054251 HDNNILPG_00007 5922 3 Skin 0.43 protein_coding synonymous_variant LOW 213C>T Asp71Asp
M0054252 HDNNILPG_00007 5925 4 Skin 0.57 protein_coding synonymous_variant LOW 216A>G Leu72Leu
M0054253 HDNNILPG_00007 5955 4 Skin 0.57 protein_coding synonymous_variant LOW 246T>C Ala82Ala
M0054254 HDNNILPG_00007 6210 4 Skin 0.57 protein_coding synonymous_variant LOW 501G>A Glu167Glu
M0054255 HDNNILPG_00007 6253 4 Skin 0.57 protein_coding missense_variant MODERATE 544A>G Thr182Ala
M0054256 HDNNILPG_00007 6264 4 Skin 0.57 protein_coding synonymous_variant LOW 555T>C Val185Val
M0054257 HDNNILPG_00007 6279 4 Skin 0.57 protein_coding synonymous_variant LOW 570A>G Glu190Glu
M0054258 HDNNILPG_00007 6282 4 Skin 0.57 protein_coding synonymous_variant LOW 573C>T Arg191Arg
M0054259 HDNNILPG_00007 6297 4 Skin 0.57 protein_coding synonymous_variant LOW 588G>A Gly196Gly
M0054260 HDNNILPG_00007 6321 4 Skin 0.57 protein_coding synonymous_variant LOW 612T>C Arg204Arg
M0054261 HDNNILPG_00007 6368 4 Skin 0.57 protein_coding missense_variant MODERATE 659A>C Gln220Pro
M0054262 HDNNILPG_00007 6402 4 Skin 0.57 protein_coding synonymous_variant LOW 693T>C Arg231Arg
M0054263 HDNNILPG_00007 6499 4 Skin 0.57 protein_coding synonymous_variant LOW 790T>C Leu264Leu
M0054264 HDNNILPG_00007 6501 3 Skin 0.43 protein_coding synonymous_variant LOW 792G>A Leu264Leu
M0054265 HDNNILPG_00007 6537 4 Skin 0.57 protein_coding synonymous_variant LOW 828T>C Pro276Pro
M0054266 HDNNILPG_00007 6935 4 Skin 0.57 protein_coding missense_variant MODERATE 1226A>C Asp409Ala
M0054267 HDNNILPG_00007 6939 4 Skin 0.57 protein_coding synonymous_variant LOW 1230C>T Pro410Pro
M0054268 HDNNILPG_00007 6954 4 Skin 0.57 protein_coding synonymous_variant LOW 1245C>T Pro415Pro
M0054269 HDNNILPG_00008 7091 3 Skin 0.43 protein_coding synonymous_variant LOW 108G>A Val36Val
M0054270 HDNNILPG_00008 7094 4 Skin 0.57 protein_coding synonymous_variant LOW 111T>C Asp37Asp
M0054271 HDNNILPG_00008 7097 3 Skin 0.43 protein_coding synonymous_variant LOW 114T>C Ala38Ala
M0054272 HDNNILPG_00008 7172 4 Skin 0.57 protein_coding synonymous_variant LOW 189T>C Asn63Asn
M0054273 HDNNILPG_00008 7178 4 Skin 0.57 protein_coding synonymous_variant LOW 195T>C Val65Val
M0054274 HDNNILPG_00008 7211 4 Skin 0.57 protein_coding synonymous_variant LOW 228T>C Val76Val
M0054275 HDNNILPG_00008 7214 3 Skin 0.43 protein_coding synonymous_variant LOW 231T>C Pro77Pro
M0054276 HDNNILPG_00008 7265 3 Skin 0.43 protein_coding synonymous_variant LOW 282C>T Tyr94Tyr
M0054277 HDNNILPG_00008 7413 4 Skin 0.57 protein_coding synonymous_variant LOW 430T>C Leu144Leu
M0054278 HDNNILPG_00008 7436 4 Skin 0.57 protein_coding synonymous_variant LOW 453C>T His151His
M0054279 HDNNILPG_00008 7463 4 Skin 0.57 protein_coding synonymous_variant LOW 480A>G Gln160Gln
M0054280 HDNNILPG_00008 7562 4 Skin 0.57 protein_coding synonymous_variant LOW 579A>G Pro193Pro
M0054281 HDNNILPG_00008 7655 4 Skin 0.57 protein_coding synonymous_variant LOW 672A>G Leu224Leu
M0054282 HDNNILPG_00008 7736 3 Skin 0.43 protein_coding synonymous_variant LOW 753C>T Gly251Gly
M0054283 HDNNILPG_00008 7739 3 Skin 0.43 protein_coding synonymous_variant LOW 756T>C Asp252Asp
M0054284 HDNNILPG_00008 7754 3 Skin 0.43 protein_coding synonymous_variant LOW 771C>G Val257Val
M0054285 HDNNILPG_00008 7910 4 Skin 0.57 protein_coding synonymous_variant LOW 927A>G Ala309Ala
M0054286 HDNNILPG_00008 8024 4 Skin 0.57 protein_coding synonymous_variant LOW 1041A>C Ile347Ile
M0054287 HDNNILPG_00008 8160 3 Skin 0.43 protein_coding synonymous_variant LOW 1177C>T Leu393Leu
M0054288 HDNNILPG_00008 8216 4 Skin 0.57 protein_coding synonymous_variant LOW 1233A>T Ile411Ile
M0054289 HDNNILPG_00008 8513 4 Skin 0.57 protein_coding synonymous_variant LOW 1530T>G Pro510Pro
M0054290 HDNNILPG_00008 8888 3 Skin 0.43 protein_coding synonymous_variant LOW 1905G>A Gln635Gln
M0054291 HDNNILPG_00008 8939 4 Skin 0.57 protein_coding synonymous_variant LOW 1956T>C Thr652Thr
M0054292 HDNNILPG_00008 9110 3 Skin 0.43 protein_coding synonymous_variant LOW 2127A>G Gly709Gly
M0054293 HDNNILPG_00008 9113 3 Skin 0.43 protein_coding synonymous_variant LOW 2130T>C Val710Val
M0054294 HDNNILPG_00008 9116 3 Skin 0.43 protein_coding synonymous_variant LOW 2133T>G Thr711Thr
M0054295 HDNNILPG_00008 9119 3 Skin 0.43 protein_coding synonymous_variant LOW 2136G>A Ser712Ser
M0054296 HDNNILPG_00008 9170 3 Skin 0.43 protein_coding missense_variant MODERATE 2187T>G His729Gln
M0054297 HDNNILPG_00008 9209 3 Skin 0.43 protein_coding synonymous_variant LOW 2226C>T Asp742Asp
M0054298 HDNNILPG_00008 9216 4 Skin 0.57 protein_coding synonymous_variant LOW 2233T>C Leu745Leu
M0054299 HDNNILPG_00008 9221 3 Skin 0.43 protein_coding synonymous_variant LOW 2238T>C Phe746Phe
M0054300 HDNNILPG_00008 9224 3 Skin 0.43 protein_coding synonymous_variant LOW 2241T>C Val747Val
M0054301 HDNNILPG_00008 9317 3 Skin 0.43 protein_coding synonymous_variant LOW 2334T>C Asp778Asp
M0054302 HDNNILPG_00008 9327 3 Skin 0.43 protein_coding missense_variant MODERATE 2344C>A Pro782Thr
M0054303 HDNNILPG_00008 9339 3 Skin 0.43 protein_coding synonymous_variant LOW 2356T>C Leu786Leu
M0054304 HDNNILPG_00008 9398 3 Skin 0.43 protein_coding synonymous_variant LOW 2415A>G Lys805Lys
M0054305 HDNNILPG_00008 9479 3 Skin 0.43 protein_coding synonymous_variant LOW 2496C>T Asp832Asp
M0054306 HDNNILPG_00008 9485 3 Skin 0.43 protein_coding synonymous_variant LOW 2502G>C Val834Val
M0054307 HDNNILPG_00008 9527 3 Skin 0.43 protein_coding synonymous_variant LOW 2544G>A Val848Val
M0054308 HDNNILPG_00008 9550 4 Skin 0.57 protein_coding missense_variant MODERATE 2567C>T Ala856Val
M0054309 HDNNILPG_00008 9572 4 Skin 0.57 protein_coding synonymous_variant LOW 2589A>G Glu863Glu
M0054310 HDNNILPG_00008 9642 4 Skin 0.57 protein_coding synonymous_variant LOW 2659T>C Leu887Leu
M0054311 HDNNILPG_00008 9675 4 Skin 0.57 protein_coding synonymous_variant LOW 2692C>T Leu898Leu
M0054312 HDNNILPG_00008 9747 4 Skin 0.57 protein_coding synonymous_variant LOW 2764T>C Leu922Leu
M0054313 HDNNILPG_00008 9797 3 Skin 0.43 protein_coding synonymous_variant LOW 2814G>A Ala938Ala
M0054314 HDNNILPG_00008 9800 3 Skin 0.43 protein_coding synonymous_variant LOW 2817G>A Glu939Glu
M0054315 HDNNILPG_00008 9833 4 Skin 0.57 protein_coding synonymous_variant LOW 2850T>C His950His
M0054316 HDNNILPG_00008 9839 4 Skin 0.57 protein_coding synonymous_variant LOW 2856T>C Ile952Ile
M0054317 HDNNILPG_00008 9905 3 Skin 0.43 protein_coding synonymous_variant LOW 2922T>C Tyr974Tyr
M0054318 HDNNILPG_00008 9908 3 Skin 0.43 protein_coding synonymous_variant LOW 2925G>A Gln975Gln
M0054319 HDNNILPG_00008 9917 4 Skin 0.57 protein_coding synonymous_variant LOW 2934A>G Val978Val
M0054320 HDNNILPG_00008 9926 4 Skin 0.57 protein_coding synonymous_variant LOW 2943T>G Val981Val
M0054321 HDNNILPG_00008 10007 3 Skin 0.43 protein_coding synonymous_variant LOW 3024A>G Val1008Val
M0054322 HDNNILPG_00008 10059 3 Skin 0.43 protein_coding synonymous_variant LOW 3076C>T Leu1026Leu
M0054323 HDNNILPG_00008 10124 4 Skin 0.57 protein_coding synonymous_variant LOW 3141T>C Arg1047Arg
M0054324 HDNNILPG_00008 10133 4 Skin 0.57 protein_coding splice_region_variant&stop_retained_variant LOW 3150G>A Ter1050Ter
M0054325 HDNNILPG_00049 62266 3 Skin 0.43 protein_coding synonymous_variant LOW 486A>C Leu162Leu
M0054326 HDNNILPG_00049 62281 3 Skin 0.43 protein_coding synonymous_variant LOW 471A>C Thr157Thr
M0054327 HDNNILPG_00049 62287 3 Skin 0.43 protein_coding synonymous_variant LOW 465A>T Arg155Arg
M0054328 HDNNILPG_00049 62348 3 Skin 0.43 protein_coding missense_variant MODERATE 404A>G Asn135Ser
M0054329 HDNNILPG_00049 62395 3 Skin 0.43 protein_coding synonymous_variant LOW 357C>A Val119Val
M0054330 HDNNILPG_00049 62434 3 Skin 0.43 protein_coding synonymous_variant LOW 318A>G Thr106Thr
M0054331 HDNNILPG_00049 62437 3 Skin 0.43 protein_coding synonymous_variant LOW 315G>T Ala105Ala
M0054332 HDNNILPG_00049 62473 3 Skin 0.43 protein_coding synonymous_variant LOW 279G>C Pro93Pro
M0054333 HDNNILPG_00049 62533 3 Skin 0.43 protein_coding synonymous_variant LOW 219A>C Thr73Thr
M0054334 HDNNILPG_00049 62536 3 Skin 0.43 protein_coding synonymous_variant LOW 216T>C Ala72Ala
M0054335 HDNNILPG_00046 62808 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4008C>T None
M0054336 HDNNILPG_00046 62821 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4021A>T None
M0054337 HDNNILPG_00050 65125 3 Skin 0.43 protein_coding missense_variant MODERATE 1847T>C Val616Ala
M0054338 HDNNILPG_00051 65814 3 Skin 0.43 protein_coding synonymous_variant LOW 474A>G Ser158Ser
M0054339 HDNNILPG_00051 65817 3 Skin 0.43 protein_coding synonymous_variant LOW 477T>C Phe159Phe
M0054340 HDNNILPG_00051 65826 3 Skin 0.43 protein_coding synonymous_variant LOW 486T>C Ala162Ala
M0054341 HDNNILPG_00051 65979 3 Skin 0.43 protein_coding synonymous_variant LOW 639A>G Glu213Glu
M0054342 HDNNILPG_00051 65985 3 Skin 0.43 protein_coding synonymous_variant LOW 645G>T Val215Val
M0054343 HDNNILPG_00051 66093 3 Skin 0.43 protein_coding synonymous_variant LOW 753T>A Val251Val
M0054344 HDNNILPG_00051 66105 3 Skin 0.43 protein_coding synonymous_variant LOW 765C>T Arg255Arg
M0054345 HDNNILPG_00051 66141 3 Skin 0.43 protein_coding synonymous_variant LOW 801A>G Leu267Leu
M0054346 HDNNILPG_00049 66218 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -3467A>T None
M0054347 HDNNILPG_00052 66294 3 Skin 0.43 protein_coding missense_variant MODERATE 789G>T Glu263Asp
M0054348 HDNNILPG_00052 66543 3 Skin 0.43 protein_coding synonymous_variant LOW 540A>G Gln180Gln
M0054349 HDNNILPG_00052 66743 3 Skin 0.43 protein_coding missense_variant MODERATE 340A>C Thr114Pro
M0054350 HDNNILPG_00052 66771 3 Skin 0.43 protein_coding synonymous_variant LOW 312C>T Val104Val
M0054351 HDNNILPG_00052 66921 3 Skin 0.43 protein_coding synonymous_variant LOW 162T>C Ser54Ser
M0054352 HDNNILPG_00052 67058 3 Skin 0.43 protein_coding missense_variant MODERATE 25C>A Gln9Lys
M0054353 HDNNILPG_00053 67155 3 Skin 0.43 protein_coding synonymous_variant LOW 1452T>C Arg484Arg
M0054354 HDNNILPG_00009 10158 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -199T>C None
M0054355 HDNNILPG_00009 10168 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -189T>C None
M0054356 HDNNILPG_00044 55883 3 Skin 0.43 protein_coding synonymous_variant LOW 1044C>T Arg348Arg
M0054357 HDNNILPG_00044 55937 3 Skin 0.43 protein_coding synonymous_variant LOW 1098G>A Arg366Arg
M0054358 HDNNILPG_00044 55940 3 Skin 0.43 protein_coding synonymous_variant LOW 1101G>A Ala367Ala
M0054359 HDNNILPG_00044 55994 3 Skin 0.43 protein_coding synonymous_variant LOW 1155A>G Glu385Glu
M0054360 HDNNILPG_00044 56069 3 Skin 0.43 protein_coding synonymous_variant LOW 1230T>C Ala410Ala
M0054361 HDNNILPG_00044 56079 3 Skin 0.43 protein_coding missense_variant MODERATE 1240A>G Thr414Ala
M0054362 HDNNILPG_00044 56084 3 Skin 0.43 protein_coding synonymous_variant LOW 1245A>G Ala415Ala
M0054363 HDNNILPG_00044 56129 3 Skin 0.43 protein_coding synonymous_variant LOW 1290C>T Thr430Thr
M0054364 HDNNILPG_00001 1506 3 Skin 0.43 protein_coding missense_variant MODERATE 1054C>A Gln352Lys
M0054365 HDNNILPG_00001 1514 3 Skin 0.43 protein_coding synonymous_variant LOW 1062A>G Pro354Pro
M0054366 HDNNILPG_00001 1516 3 Skin 0.43 protein_coding missense_variant MODERATE 1064A>C Glu355Ala
M0054367 HDNNILPG_00001 1517 3 Skin 0.43 protein_coding synonymous_variant LOW 1065A>G Glu355Glu
M0054368 HDNNILPG_00001 1523 3 Skin 0.43 protein_coding synonymous_variant LOW 1071G>T Val357Val
M0054369 HDNNILPG_00001 1529 3 Skin 0.43 protein_coding synonymous_variant LOW 1077G>A Glu359Glu
M0054370 HDNNILPG_00001 1538 3 Skin 0.43 protein_coding synonymous_variant LOW 1086G>C Arg362Arg
M0054371 HDNNILPG_00001 1562 3 Skin 0.43 protein_coding synonymous_variant LOW 1110C>T Tyr370Tyr
M0054372 HDNNILPG_00004 1575 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2234A>G None
M0054373 HDNNILPG_00004 1598 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2211T>C None
M0054374 HDNNILPG_00002 1649 3 Skin 0.43 protein_coding synonymous_variant LOW 1423C>T Leu475Leu
M0054375 HDNNILPG_00002 1665 3 Skin 0.43 protein_coding synonymous_variant LOW 1407G>T Thr469Thr
M0054376 HDNNILPG_00002 1668 3 Skin 0.43 protein_coding synonymous_variant LOW 1404T>C Ser468Ser
M0054377 HDNNILPG_00003 3229 3 Skin 0.43 protein_coding synonymous_variant LOW 516C>T Arg172Arg
M0054378 HDNNILPG_00005 4016 3 Skin 0.43 protein_coding synonymous_variant LOW 99A>G Pro33Pro
M0054379 HDNNILPG_00005 4467 3 Skin 0.43 protein_coding synonymous_variant LOW 550T>C Leu184Leu
M0054380 HDNNILPG_00005 4934 3 Skin 0.43 protein_coding synonymous_variant LOW 1017C>T Ile339Ile
M0054381 HDNNILPG_00007 6177 3 Skin 0.43 protein_coding synonymous_variant LOW 468G>C Pro156Pro
M0054382 HDNNILPG_00007 6291 3 Skin 0.43 protein_coding synonymous_variant LOW 582T>C Leu194Leu
M0054383 HDNNILPG_00008 7487 3 Skin 0.43 protein_coding synonymous_variant LOW 504G>A Leu168Leu
M0054384 HDNNILPG_00008 7616 3 Skin 0.43 protein_coding synonymous_variant LOW 633T>C Asp211Asp
M0054385 HDNNILPG_00008 7949 3 Skin 0.43 protein_coding synonymous_variant LOW 966C>T Val322Val
M0054386 HDNNILPG_00008 8075 3 Skin 0.43 protein_coding synonymous_variant LOW 1092G>A Leu364Leu
M0054387 HDNNILPG_00008 8114 3 Skin 0.43 protein_coding synonymous_variant LOW 1131C>T Ala377Ala
M0054388 HDNNILPG_00008 8120 3 Skin 0.43 protein_coding synonymous_variant LOW 1137C>T Ile379Ile
M0054389 HDNNILPG_00008 8579 3 Skin 0.43 protein_coding synonymous_variant LOW 1596G>A Val532Val
M0054390 HDNNILPG_00008 8681 3 Skin 0.43 protein_coding synonymous_variant LOW 1698C>T Asn566Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
HDNNILPG_00005 VFG034679 Ibes 75.7 1.4e-193 1 461 1.0 1.0022 Invasion Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC experiment
HDNNILPG_00005 VFG034663 Ibes 76.4 1.5e-194 1 461 1.0 1.0022 Invasion Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
HDNNILPG_00003 Copper (Cu), Silver (Ag) 94.7 7.4e-122 1 227 1.0000 1.0000 experiment
HDNNILPG_00005 Copper (Cu), Silver (Ag) 76.6 1.3e-194 1 458 0.9935 1.0022 experiment
HDNNILPG_00007 Copper (Cu), Silver (Ag) 76.1 1.9e-179 6 420 0.9952 1.0270 experiment
HDNNILPG_00008 Copper (Cu), Silver (Ag) 89.4 0 1 1047 0.9981 1.0000 experiment
HDNNILPG_00002 Copper (Cu) 94.8 2e-258 1 480 1.0000 1.0000 prediction
HDNNILPG_00003 Copper (Cu), Silver (Ag) 100 1e-124 1 227 1.0000 1.0000 prediction
HDNNILPG_00005 Copper (Cu), Silver (Ag) 76.6 1.9e-194 1 461 1.0000 1.0022 prediction
HDNNILPG_00007 Copper (Cu), Silver (Ag) 77 2.1e-179 6 420 0.9952 1.0270 prediction
HDNNILPG_00008 Silver (Ag) 93.3 0 1 1049 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
HDNNILPG_00005 1.B.17.3.5 76.6 5e-193 1 458 0.9935 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.17 The Outer Membrane Factor (OMF) Family
HDNNILPG_00007 2.A.6.1.4 76.1 7.1e-178 6 420 0.9881 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
HDNNILPG_00008 2.A.6.1.4 89.4 0 1 1047 0.9981 2.5725 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
HDNNILPG_00034 3.A.17.1.1 92.3 0 1 1170 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.17 The Phage T7 Injectisome (T7 Injectisome) Family
HDNNILPG_00056 3.A.1.152.9 95.6 2.1e-191 1 360 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HDNNILPG_00057 3.A.1.152.9 94.2 7e-190 1 364 0.9973 1.0111 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily