Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2754
  Reference Plasmid   1111525849862212_bin.12__k141_187785
  Reference Plasmid Size   3104
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0055663 CINOCOJH_00001 156 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -158T>G None
M0055664 CINOCOJH_00001 168 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -146A>G None
M0055665 CINOCOJH_00001 169 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -145T>C None
M0055666 CINOCOJH_00001 185 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -129C>T None
M0055667 CINOCOJH_00001 186 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -128T>G None
M0055668 CINOCOJH_00001 245 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -69G>A None
M0055669 CINOCOJH_00001 455 4 Skin 0.80 protein_coding missense_variant MODERATE 142T>G Ser48Ala
M0055670 CINOCOJH_00001 520 5 Skin 1.00 protein_coding synonymous_variant LOW 207G>T Val69Val
M0055671 CINOCOJH_00001 536 4 Skin 0.80 protein_coding missense_variant MODERATE 223G>A Val75Ile
M0055672 CINOCOJH_00005 2497 3 Skin 0.60 protein_coding missense_variant MODERATE 496G>A Glu166Lys
M0055673 CINOCOJH_00005 2538 4 Skin 0.80 protein_coding missense_variant MODERATE 537G>C Lys179Asn
M0055674 CINOCOJH_00005 2541 3 Skin 0.60 protein_coding synonymous_variant LOW 540G>A Arg180Arg
M0055675 CINOCOJH_00005 2545 3 Skin 0.60 protein_coding missense_variant MODERATE 544T>A Ser182Thr
M0055676 CINOCOJH_00005 2560 4 Skin 0.80 protein_coding missense_variant MODERATE 559C>T His187Tyr
M0055677 CINOCOJH_00001 445 3 Skin 0.60 protein_coding synonymous_variant LOW 132T>C Ala44Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term