Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2758
  Reference Plasmid   1111525849862212_bin.9__k141_247197
  Reference Plasmid Size   27656
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056020 FPCPEAFC_00007 5310 4 Skin 0.11 protein_coding synonymous_variant LOW 283T>C Leu95Leu
M0056021 FPCPEAFC_00008 6017 5 Skin 0.13 protein_coding missense_variant MODERATE 247A>G Arg83Gly
M0056022 FPCPEAFC_00009 6413 3 Skin 0.08 protein_coding missense_variant MODERATE 17T>C Leu6Pro
M0056023 FPCPEAFC_00024 24808 7 Skin 0.18 protein_coding synonymous_variant LOW 327A>G Glu109Glu
M0056024 FPCPEAFC_00024 25069 3 Skin 0.08 protein_coding synonymous_variant LOW 66G>C Ala22Ala
M0056025 FPCPEAFC_00024 25096 3 Skin 0.08 protein_coding synonymous_variant LOW 39C>A Ala13Ala
M0056026 FPCPEAFC_00024 25097 3 Skin 0.08 protein_coding missense_variant MODERATE 38C>T Ala13Val
M0056027 FPCPEAFC_00024 25099 3 Skin 0.08 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0056028 FPCPEAFC_00024 25102 3 Skin 0.08 protein_coding synonymous_variant LOW 33C>A Ala11Ala
M0056029 FPCPEAFC_00024 25134 3 Skin 0.08 protein_coding start_lost HIGH 1A>G Met1?
M0056030 FPCPEAFC_00012 10596 19 Skin 0.50 protein_coding synonymous_variant LOW 1293T>C Asp431Asp
M0056031 FPCPEAFC_00010 12023 6 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -3906G>A None
M0056032 FPCPEAFC_00017 14172 6 Skin 0.16 protein_coding missense_variant MODERATE 32C>G Pro11Arg
M0056033 FPCPEAFC_00024 24677 4 Skin 0.11 protein_coding missense_variant MODERATE 458G>C Ser153Thr
M0056034 FPCPEAFC_00024 24710 4 Skin 0.11 protein_coding missense_variant MODERATE 425T>C Val142Ala
M0056035 FPCPEAFC_00024 24714 4 Skin 0.11 protein_coding missense_variant MODERATE 421C>G Pro141Ala
M0056036 FPCPEAFC_00024 24727 4 Skin 0.11 protein_coding synonymous_variant LOW 408G>A Arg136Arg
M0056037 FPCPEAFC_00024 24745 4 Skin 0.11 protein_coding synonymous_variant LOW 390C>T Arg130Arg
M0056038 FPCPEAFC_00024 24763 4 Skin 0.11 protein_coding synonymous_variant LOW 372A>C Ala124Ala
M0056039 FPCPEAFC_00024 24786 4 Skin 0.11 protein_coding missense_variant MODERATE 349A>G Thr117Ala
M0056040 FPCPEAFC_00024 24797 4 Skin 0.11 protein_coding missense_variant MODERATE 338C>T Pro113Leu
M0056041 FPCPEAFC_00024 24820 4 Skin 0.11 protein_coding synonymous_variant LOW 315C>T Gly105Gly
M0056042 FPCPEAFC_00024 24827 4 Skin 0.11 protein_coding missense_variant MODERATE 308G>T Gly103Val
M0056043 FPCPEAFC_00024 24842 4 Skin 0.11 protein_coding missense_variant MODERATE 293C>G Thr98Ser
M0056044 FPCPEAFC_00024 24846 4 Skin 0.11 protein_coding synonymous_variant LOW 289T>C Leu97Leu
M0056045 FPCPEAFC_00020 25654 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4568T>C None
M0056046 FPCPEAFC_00018 14650 6 Skin 0.16 protein_coding synonymous_variant LOW 1509C>T Ala503Ala
M0056047 FPCPEAFC_00021 21862 5 Skin 0.13 protein_coding missense_variant MODERATE 251C>A Ala84Glu
M0056048 FPCPEAFC_00021 21873 4 Skin 0.11 protein_coding synonymous_variant LOW 240G>T Gly80Gly
M0056049 FPCPEAFC_00021 21888 5 Skin 0.13 protein_coding synonymous_variant LOW 225G>T Pro75Pro
M0056050 FPCPEAFC_00024 24496 5 Skin 0.13 protein_coding synonymous_variant LOW 639G>C Thr213Thr
M0056051 FPCPEAFC_00021 21279 3 Skin 0.08 protein_coding synonymous_variant LOW 834G>A Leu278Leu
M0056052 FPCPEAFC_00021 21288 3 Skin 0.08 protein_coding synonymous_variant LOW 825G>A Gln275Gln
M0056053 FPCPEAFC_00021 21381 3 Skin 0.08 protein_coding synonymous_variant LOW 732T>G Leu244Leu
M0056054 FPCPEAFC_00021 21408 3 Skin 0.08 protein_coding synonymous_variant LOW 705G>C Ala235Ala
M0056055 FPCPEAFC_00021 21459 3 Skin 0.08 protein_coding synonymous_variant LOW 654G>A Leu218Leu
M0056056 FPCPEAFC_00021 21792 3 Skin 0.08 protein_coding missense_variant MODERATE 321G>C Met107Ile
M0056057 FPCPEAFC_00021 21948 5 Skin 0.13 protein_coding synonymous_variant LOW 165T>C Ile55Ile
M0056058 FPCPEAFC_00016 13239 4 Skin 0.11 protein_coding synonymous_variant LOW 171C>G Pro57Pro
M0056059 FPCPEAFC_00017 14084 3 Skin 0.08 protein_coding synonymous_variant LOW 120C>G Gly40Gly
M0056060 FPCPEAFC_00018 15859 3 Skin 0.08 protein_coding synonymous_variant LOW 300T>C Gly100Gly
M0056061 FPCPEAFC_00018 15879 3 Skin 0.08 protein_coding synonymous_variant LOW 280C>T Leu94Leu
M0056062 FPCPEAFC_00018 15897 3 Skin 0.08 protein_coding missense_variant MODERATE 262A>G Thr88Ala
M0056063 FPCPEAFC_00012 9495 3 Skin 0.08 protein_coding synonymous_variant LOW 192A>G Ala64Ala
M0056064 FPCPEAFC_00016 14424 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1015G>A None
M0056065 FPCPEAFC_00016 14427 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1018C>A None
M0056066 FPCPEAFC_00016 14443 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1034C>T None
M0056067 FPCPEAFC_00016 14444 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1035C>T None
M0056068 FPCPEAFC_00018 14806 3 Skin 0.08 protein_coding synonymous_variant LOW 1353A>G Ala451Ala
M0056069 FPCPEAFC_00019 18119 3 Skin 0.08 protein_coding missense_variant MODERATE 640A>G Thr214Ala
M0056070 FPCPEAFC_00019 18201 3 Skin 0.08 protein_coding synonymous_variant LOW 558G>C Thr186Thr
M0056071 FPCPEAFC_00019 18234 3 Skin 0.08 protein_coding synonymous_variant LOW 525C>A Pro175Pro
M0056072 FPCPEAFC_00020 20160 4 Skin 0.11 protein_coding synonymous_variant LOW 927C>G Pro309Pro
M0056073 FPCPEAFC_00019 22207 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3449A>G None
M0056074 FPCPEAFC_00019 22213 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3455C>T None
M0056075 FPCPEAFC_00022 22597 3 Skin 0.08 protein_coding synonymous_variant LOW 348G>T Val116Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term