Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2759
  Reference Plasmid   1111525849862212_bin.9__k141_320306
  Reference Plasmid Size   13587
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056076 DEIFKIKN_00003 3816 3 Skin 0.12 protein_coding synonymous_variant LOW 2412A>G Ala804Ala
M0056077 DEIFKIKN_00003 3909 3 Skin 0.12 protein_coding synonymous_variant LOW 2505T>C Ile835Ile
M0056078 DEIFKIKN_00002 648 3 Skin 0.12 protein_coding missense_variant MODERATE 536C>T Ala179Val
M0056079 DEIFKIKN_00002 684 3 Skin 0.12 protein_coding missense_variant MODERATE 500A>G Asp167Gly
M0056080 DEIFKIKN_00002 743 3 Skin 0.12 protein_coding missense_variant MODERATE 441G>C Glu147Asp
M0056081 DEIFKIKN_00002 756 4 Skin 0.15 protein_coding missense_variant MODERATE 428C>T Ala143Val
M0056082 DEIFKIKN_00002 851 4 Skin 0.15 protein_coding synonymous_variant LOW 333C>G Ala111Ala
M0056083 DEIFKIKN_00002 882 3 Skin 0.12 protein_coding missense_variant MODERATE 302G>A Arg101His
M0056084 DEIFKIKN_00002 884 4 Skin 0.15 protein_coding synonymous_variant LOW 300T>C Asp100Asp
M0056085 DEIFKIKN_00002 888 3 Skin 0.12 protein_coding missense_variant MODERATE 296A>C Asp99Ala
M0056086 DEIFKIKN_00002 894 4 Skin 0.15 protein_coding missense_variant MODERATE 290A>G Lys97Arg
M0056087 DEIFKIKN_00002 917 4 Skin 0.15 protein_coding synonymous_variant LOW 267C>A Gly89Gly
M0056088 DEIFKIKN_00002 935 4 Skin 0.15 protein_coding synonymous_variant LOW 249T>G Leu83Leu
M0056089 DEIFKIKN_00002 941 3 Skin 0.12 protein_coding synonymous_variant LOW 243T>C Ala81Ala
M0056090 DEIFKIKN_00002 974 4 Skin 0.15 protein_coding synonymous_variant LOW 210A>G Lys70Lys
M0056091 DEIFKIKN_00002 1053 3 Skin 0.12 protein_coding missense_variant MODERATE 131T>G Leu44Arg
M0056092 DEIFKIKN_00002 1207 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -24A>T None
M0056093 DEIFKIKN_00002 1242 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -59A>G None
M0056094 DEIFKIKN_00002 1252 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -69T>C None
M0056095 DEIFKIKN_00002 1255 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -72C>A None
M0056096 DEIFKIKN_00002 1256 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -73T>G None
M0056097 DEIFKIKN_00002 1257 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -74A>G None
M0056098 DEIFKIKN_00002 1284 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -101T>C None
M0056099 DEIFKIKN_00003 1608 5 Skin 0.19 protein_coding synonymous_variant LOW 204T>G Ala68Ala
M0056100 DEIFKIKN_00003 1618 4 Skin 0.15 protein_coding synonymous_variant LOW 214C>T Leu72Leu
M0056101 DEIFKIKN_00003 1650 4 Skin 0.15 protein_coding synonymous_variant LOW 246C>T Arg82Arg
M0056102 DEIFKIKN_00003 1674 4 Skin 0.15 protein_coding synonymous_variant LOW 270C>G Pro90Pro
M0056103 DEIFKIKN_00003 1728 3 Skin 0.12 protein_coding synonymous_variant LOW 324G>A Glu108Glu
M0056104 DEIFKIKN_00003 1944 3 Skin 0.12 protein_coding synonymous_variant LOW 540T>C Tyr180Tyr
M0056105 DEIFKIKN_00003 3252 3 Skin 0.12 protein_coding synonymous_variant LOW 1848G>A Glu616Glu
M0056106 DEIFKIKN_00003 3279 3 Skin 0.12 protein_coding synonymous_variant LOW 1875C>T Gly625Gly
M0056107 DEIFKIKN_00004 5146 5 Skin 0.19 protein_coding synonymous_variant LOW 298C>T Leu100Leu
M0056108 DEIFKIKN_00002 5522 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4339T>C None
M0056109 DEIFKIKN_00002 800 3 Skin 0.12 protein_coding synonymous_variant LOW 384T>C Asp128Asp
M0056110 DEIFKIKN_00003 2106 3 Skin 0.12 protein_coding synonymous_variant LOW 702T>C Ile234Ile
M0056111 DEIFKIKN_00003 2136 3 Skin 0.12 protein_coding synonymous_variant LOW 732C>G Gly244Gly
M0056112 DEIFKIKN_00003 2763 3 Skin 0.12 protein_coding synonymous_variant LOW 1359A>C Ile453Ile
M0056113 DEIFKIKN_00003 2859 3 Skin 0.12 protein_coding synonymous_variant LOW 1455C>T Asp485Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term