Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2760
  Reference Plasmid   1111525849862289_bin.1__k141_732606
  Reference Plasmid Size   2379
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056114 HLPHGCBN_00001 58 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -124G>A None
M0056115 HLPHGCBN_00001 87 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -95T>C None
M0056116 HLPHGCBN_00001 99 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -83T>C None
M0056117 HLPHGCBN_00001 176 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -6A>C None
M0056118 HLPHGCBN_00001 295 3 Skin 0.50 protein_coding synonymous_variant LOW 114C>A Pro38Pro
M0056119 HLPHGCBN_00001 296 3 Skin 0.50 protein_coding missense_variant MODERATE 115G>C Val39Leu
M0056120 HLPHGCBN_00001 370 4 Skin 0.67 protein_coding synonymous_variant LOW 189T>C Thr63Thr
M0056121 HLPHGCBN_00001 391 4 Skin 0.67 protein_coding missense_variant MODERATE 210G>T Leu70Phe
M0056122 HLPHGCBN_00001 562 4 Skin 0.67 protein_coding synonymous_variant LOW 381C>G Ser127Ser
M0056123 HLPHGCBN_00001 565 4 Skin 0.67 protein_coding synonymous_variant LOW 384A>G Leu128Leu
M0056124 HLPHGCBN_00001 758 4 Skin 0.67 protein_coding missense_variant MODERATE 577G>A Ala193Thr
M0056125 HLPHGCBN_00001 788 4 Skin 0.67 protein_coding synonymous_variant LOW 607C>T Leu203Leu
M0056126 HLPHGCBN_00001 886 4 Skin 0.67 protein_coding synonymous_variant LOW 705T>C Asp235Asp
M0056127 HLPHGCBN_00001 907 3 Skin 0.50 protein_coding synonymous_variant LOW 726T>C Ile242Ile
M0056128 HLPHGCBN_00001 931 3 Skin 0.50 protein_coding synonymous_variant LOW 750G>A Gln250Gln
M0056129 HLPHGCBN_00001 784 3 Skin 0.50 protein_coding synonymous_variant LOW 603A>G Gln201Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term