Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2763
  Reference Plasmid   1111525849862289_bin.8__k141_413979
  Reference Plasmid Size   119791
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056140 GIGGKONF_00024 19196 3 Skin 0.18 protein_coding missense_variant MODERATE 227G>A Arg76Lys
M0056141 GIGGKONF_00025 19532 4 Skin 0.24 protein_coding missense_variant MODERATE 16A>G Ile6Val
M0056142 GIGGKONF_00025 19579 4 Skin 0.24 protein_coding synonymous_variant LOW 63T>C Phe21Phe
M0056143 GIGGKONF_00027 20291 4 Skin 0.24 protein_coding missense_variant MODERATE 121A>G Asn41Asp
M0056144 GIGGKONF_00028 20630 3 Skin 0.18 protein_coding synonymous_variant LOW 192A>G Ser64Ser
M0056145 GIGGKONF_00028 20744 4 Skin 0.24 protein_coding synonymous_variant LOW 306C>T Ser102Ser
M0056146 GIGGKONF_00028 21212 4 Skin 0.24 protein_coding synonymous_variant LOW 774T>C Leu258Leu
M0056147 GIGGKONF_00028 21878 4 Skin 0.24 protein_coding synonymous_variant LOW 1440G>A Glu480Glu
M0056148 GIGGKONF_00028 21879 3 Skin 0.18 protein_coding synonymous_variant LOW 1441C>T Leu481Leu
M0056149 GIGGKONF_00058 64088 3 Skin 0.18 protein_coding missense_variant MODERATE 832C>A Leu278Ile
M0056150 GIGGKONF_00058 64499 3 Skin 0.18 protein_coding synonymous_variant LOW 421C>T Leu141Leu
M0056151 GIGGKONF_00058 64655 4 Skin 0.24 protein_coding missense_variant MODERATE 265A>G Ile89Val
M0056152 GIGGKONF_00058 64662 4 Skin 0.24 protein_coding synonymous_variant LOW 258C>T Cys86Cys
M0056153 GIGGKONF_00058 64706 4 Skin 0.24 protein_coding missense_variant MODERATE 214A>G Lys72Glu
M0056154 GIGGKONF_00058 64734 3 Skin 0.18 protein_coding synonymous_variant LOW 186G>A Arg62Arg
M0056155 GIGGKONF_00059 64981 4 Skin 0.24 protein_coding missense_variant MODERATE 307G>T Ala103Ser
M0056156 GIGGKONF_00024 19356 3 Skin 0.18 protein_coding missense_variant MODERATE 387T>G Ile129Met
M0056157 GIGGKONF_00025 19573 3 Skin 0.18 protein_coding synonymous_variant LOW 57A>G Glu19Glu
M0056158 GIGGKONF_00026 19913 3 Skin 0.18 protein_coding synonymous_variant LOW 45T>C Asn15Asn
M0056159 GIGGKONF_00026 19970 3 Skin 0.18 protein_coding synonymous_variant LOW 102C>T Ala34Ala
M0056160 GIGGKONF_00026 19998 3 Skin 0.18 protein_coding missense_variant MODERATE 130A>C Ile44Leu
M0056161 GIGGKONF_00026 20033 3 Skin 0.18 protein_coding synonymous_variant LOW 165C>T Ile55Ile
M0056162 GIGGKONF_00027 20204 3 Skin 0.18 protein_coding missense_variant MODERATE 34A>G Lys12Glu
M0056163 GIGGKONF_00028 21434 3 Skin 0.18 protein_coding synonymous_variant LOW 996T>C Ile332Ile
M0056164 GIGGKONF_00028 21651 3 Skin 0.18 protein_coding missense_variant MODERATE 1213C>T Leu405Phe
M0056165 GIGGKONF_00028 21653 3 Skin 0.18 protein_coding synonymous_variant LOW 1215T>G Leu405Leu
M0056166 GIGGKONF_00028 21812 3 Skin 0.18 protein_coding synonymous_variant LOW 1374T>C Asp458Asp
M0056167 GIGGKONF_00028 22049 3 Skin 0.18 protein_coding synonymous_variant LOW 1611A>G Val537Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GIGGKONF_00090 2.A.114.1.2 74.4 5.6e-203 1 484 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family