Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2771
  Reference Plasmid   1111525849862568_bin.20__k141_24006
  Reference Plasmid Size   16513
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056480 OPGMBBHF_00005 5488 3 Skin 0.50 protein_coding missense_variant MODERATE 178C>T His60Tyr
M0056481 OPGMBBHF_00007 6447 3 Skin 0.50 protein_coding missense_variant MODERATE 545T>G Leu182Arg
M0056482 OPGMBBHF_00007 6941 3 Skin 0.50 protein_coding missense_variant MODERATE 51G>C Lys17Asn
M0056483 OPGMBBHF_00004 7121 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -2606T>G None
M0056484 OPGMBBHF_00008 7524 3 Skin 0.50 protein_coding synonymous_variant LOW 27T>C Gly9Gly
M0056485 OPGMBBHF_00008 7890 3 Skin 0.50 protein_coding missense_variant MODERATE 393A>C Glu131Asp
M0056486 OPGMBBHF_00004 8123 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -3608T>C None
M0056487 OPGMBBHF_00004 8124 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -3609C>T None
M0056488 OPGMBBHF_00004 8139 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3624C>A None
M0056489 OPGMBBHF_00004 8147 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -3632A>C None
M0056490 OPGMBBHF_00004 8149 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -3634T>G None
M0056491 OPGMBBHF_00004 8151 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3636T>C None
M0056492 OPGMBBHF_00009 8350 4 Skin 0.67 protein_coding synonymous_variant LOW 1251A>G Ala417Ala
M0056493 OPGMBBHF_00009 8362 4 Skin 0.67 protein_coding synonymous_variant LOW 1239T>G Thr413Thr
M0056494 OPGMBBHF_00009 8479 3 Skin 0.50 protein_coding synonymous_variant LOW 1122A>G Ser374Ser
M0056495 OPGMBBHF_00009 8535 5 Skin 0.83 protein_coding missense_variant MODERATE 1066C>G Gln356Glu
M0056496 OPGMBBHF_00009 8800 4 Skin 0.67 protein_coding synonymous_variant LOW 801A>C Ala267Ala
M0056497 OPGMBBHF_00009 8856 4 Skin 0.67 protein_coding synonymous_variant LOW 745C>T Leu249Leu
M0056498 OPGMBBHF_00009 8941 4 Skin 0.67 protein_coding synonymous_variant LOW 660T>C Leu220Leu
M0056499 OPGMBBHF_00009 8953 3 Skin 0.50 protein_coding synonymous_variant LOW 648C>T Ile216Ile
M0056500 OPGMBBHF_00009 8956 3 Skin 0.50 protein_coding synonymous_variant LOW 645G>A Ala215Ala
M0056501 OPGMBBHF_00009 9037 3 Skin 0.50 protein_coding synonymous_variant LOW 564C>G Arg188Arg
M0056502 OPGMBBHF_00009 9052 4 Skin 0.67 protein_coding synonymous_variant LOW 549C>A Ala183Ala
M0056503 OPGMBBHF_00009 9055 4 Skin 0.67 protein_coding synonymous_variant LOW 546T>C Gly182Gly
M0056504 OPGMBBHF_00009 9089 4 Skin 0.67 protein_coding missense_variant MODERATE 512C>T Thr171Ile
M0056505 OPGMBBHF_00009 9103 4 Skin 0.67 protein_coding synonymous_variant LOW 498G>T Ala166Ala
M0056506 OPGMBBHF_00009 9107 4 Skin 0.67 protein_coding missense_variant MODERATE 494C>T Ala165Val
M0056507 OPGMBBHF_00009 9109 4 Skin 0.67 protein_coding synonymous_variant LOW 492G>A Glu164Glu
M0056508 OPGMBBHF_00009 9112 4 Skin 0.67 protein_coding synonymous_variant LOW 489C>G Val163Val
M0056509 OPGMBBHF_00009 9163 3 Skin 0.50 protein_coding synonymous_variant LOW 438C>T Ile146Ile
M0056510 OPGMBBHF_00009 9169 4 Skin 0.67 protein_coding synonymous_variant LOW 432G>C Val144Val
M0056511 OPGMBBHF_00009 9424 3 Skin 0.50 protein_coding synonymous_variant LOW 177T>C Tyr59Tyr
M0056512 OPGMBBHF_00009 8208 4 Skin 0.67 protein_coding missense_variant MODERATE 1393C>G Leu465Val
M0056513 OPGMBBHF_00005 9970 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4305A>C None
M0056514 OPGMBBHF_00011 11319 3 Skin 0.50 protein_coding synonymous_variant LOW 1257T>C His419His
M0056515 OPGMBBHF_00011 11364 3 Skin 0.50 protein_coding synonymous_variant LOW 1302T>G Val434Val
M0056516 OPGMBBHF_00011 11517 3 Skin 0.50 protein_coding synonymous_variant LOW 1455T>C Arg485Arg
M0056517 OPGMBBHF_00012 12074 3 Skin 0.50 protein_coding synonymous_variant LOW 678G>C Val226Val
M0056518 OPGMBBHF_00012 12269 3 Skin 0.50 protein_coding synonymous_variant LOW 483G>C Ala161Ala
M0056519 OPGMBBHF_00012 12659 3 Skin 0.50 protein_coding synonymous_variant LOW 93G>A Gln31Gln
M0056520 OPGMBBHF_00013 12775 3 Skin 0.50 protein_coding synonymous_variant LOW 1201T>C Leu401Leu
M0056521 OPGMBBHF_00013 12905 3 Skin 0.50 protein_coding synonymous_variant LOW 1071G>C Ala357Ala
M0056522 OPGMBBHF_00013 12959 3 Skin 0.50 protein_coding synonymous_variant LOW 1017C>G Pro339Pro
M0056523 OPGMBBHF_00009 8302 3 Skin 0.50 protein_coding missense_variant MODERATE 1299G>T Glu433Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term