Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2774
  Reference Plasmid   1111525849862568_bin.20__k141_557466
  Reference Plasmid Size   10849
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056543 PDNNCAJJ_00002 791 3 Skin 0.38 protein_coding missense_variant MODERATE 464A>G Asn155Ser
M0056544 PDNNCAJJ_00002 811 3 Skin 0.38 protein_coding missense_variant MODERATE 484A>G Arg162Gly
M0056545 PDNNCAJJ_00002 835 4 Skin 0.50 protein_coding missense_variant MODERATE 508C>T Leu170Phe
M0056546 PDNNCAJJ_00002 846 4 Skin 0.50 protein_coding synonymous_variant LOW 519G>A Leu173Leu
M0056547 PDNNCAJJ_00002 855 4 Skin 0.50 protein_coding synonymous_variant LOW 528C>T Leu176Leu
M0056548 PDNNCAJJ_00002 864 4 Skin 0.50 protein_coding synonymous_variant LOW 537A>G Gln179Gln
M0056549 PDNNCAJJ_00002 879 4 Skin 0.50 protein_coding synonymous_variant LOW 552C>G Leu184Leu
M0056550 PDNNCAJJ_00002 881 4 Skin 0.50 protein_coding missense_variant MODERATE 554A>G Asn185Ser
M0056551 PDNNCAJJ_00002 1182 4 Skin 0.50 protein_coding synonymous_variant LOW 855A>G Thr285Thr
M0056552 PDNNCAJJ_00003 2384 7 Skin 0.88 protein_coding missense_variant MODERATE 1067A>G Lys356Arg
M0056553 PDNNCAJJ_00003 2391 7 Skin 0.88 protein_coding synonymous_variant LOW 1074T>C Val358Val
M0056554 PDNNCAJJ_00004 2472 7 Skin 0.88 protein_coding upstream_gene_variant MODIFIER -230C>G None
M0056555 PDNNCAJJ_00004 2911 6 Skin 0.75 protein_coding synonymous_variant LOW 210T>C Arg70Arg
M0056556 PDNNCAJJ_00004 3133 4 Skin 0.50 protein_coding synonymous_variant LOW 432C>T Gly144Gly
M0056557 PDNNCAJJ_00004 3260 6 Skin 0.75 protein_coding synonymous_variant LOW 559C>T Leu187Leu
M0056558 PDNNCAJJ_00004 3376 6 Skin 0.75 protein_coding synonymous_variant LOW 675T>C Ser225Ser
M0056559 PDNNCAJJ_00004 3531 7 Skin 0.88 protein_coding missense_variant MODERATE 830G>A Gly277Glu
M0056560 PDNNCAJJ_00004 3533 7 Skin 0.88 protein_coding missense_variant MODERATE 832T>C Ser278Pro
M0056561 PDNNCAJJ_00006 3740 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -1262G>A None
M0056562 PDNNCAJJ_00003 1596 3 Skin 0.38 protein_coding synonymous_variant LOW 279T>C Asn93Asn
M0056563 PDNNCAJJ_00003 2338 3 Skin 0.38 protein_coding missense_variant MODERATE 1021A>C Lys341Gln
M0056564 PDNNCAJJ_00003 2418 4 Skin 0.50 protein_coding synonymous_variant LOW 1101A>G Glu367Glu
M0056565 PDNNCAJJ_00003 2373 3 Skin 0.38 protein_coding synonymous_variant LOW 1056G>A Arg352Arg
M0056566 PDNNCAJJ_00003 2376 3 Skin 0.38 protein_coding synonymous_variant LOW 1059A>G Leu353Leu
M0056567 PDNNCAJJ_00004 2834 3 Skin 0.38 protein_coding missense_variant MODERATE 133G>A Val45Met
M0056568 PDNNCAJJ_00004 2873 3 Skin 0.38 protein_coding missense_variant MODERATE 172A>G Thr58Ala
M0056569 PDNNCAJJ_00006 3862 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1140G>C None
M0056570 PDNNCAJJ_00005 4004 3 Skin 0.38 protein_coding synonymous_variant LOW 918T>G Ala306Ala
M0056571 PDNNCAJJ_00005 4019 3 Skin 0.38 protein_coding synonymous_variant LOW 903C>T Ile301Ile
M0056572 PDNNCAJJ_00005 4028 3 Skin 0.38 protein_coding synonymous_variant LOW 894A>C Thr298Thr
M0056573 PDNNCAJJ_00005 4062 3 Skin 0.38 protein_coding missense_variant MODERATE 860A>G His287Arg
M0056574 PDNNCAJJ_00005 4324 3 Skin 0.38 protein_coding synonymous_variant LOW 598A>C Arg200Arg
M0056575 PDNNCAJJ_00005 4334 3 Skin 0.38 protein_coding synonymous_variant LOW 588A>G Glu196Glu
M0056576 PDNNCAJJ_00003 2202 3 Skin 0.38 protein_coding synonymous_variant LOW 885G>T Leu295Leu
M0056577 PDNNCAJJ_00003 2205 3 Skin 0.38 protein_coding synonymous_variant LOW 888G>A Ala296Ala
M0056578 PDNNCAJJ_00003 2211 3 Skin 0.38 protein_coding synonymous_variant LOW 894T>C Thr298Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term