Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2776
  Reference Plasmid   1111525849862995_bin.12_new__k141_132669
  Reference Plasmid Size   8040
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056580 JLCGNEPB_00005 2691 3 Skin 0.33 protein_coding synonymous_variant LOW 156A>G Glu52Glu
M0056581 JLCGNEPB_00005 2713 3 Skin 0.33 protein_coding missense_variant MODERATE 178G>T Ala60Ser
M0056582 JLCGNEPB_00005 2723 3 Skin 0.33 protein_coding missense_variant MODERATE 188G>C Gly63Ala
M0056583 JLCGNEPB_00005 2784 4 Skin 0.44 protein_coding synonymous_variant LOW 249T>C Pro83Pro
M0056584 JLCGNEPB_00005 2805 4 Skin 0.44 protein_coding synonymous_variant LOW 270T>C Arg90Arg
M0056585 JLCGNEPB_00005 2901 3 Skin 0.33 protein_coding synonymous_variant LOW 366T>A Pro122Pro
M0056586 JLCGNEPB_00005 2903 3 Skin 0.33 protein_coding missense_variant MODERATE 368A>G Gln123Arg
M0056587 JLCGNEPB_00005 2911 3 Skin 0.33 protein_coding missense_variant MODERATE 376A>T Ile126Phe
M0056588 JLCGNEPB_00005 2939 3 Skin 0.33 protein_coding missense_variant MODERATE 404T>A Phe135Tyr
M0056589 JLCGNEPB_00005 2952 3 Skin 0.33 protein_coding synonymous_variant LOW 417G>A Val139Val
M0056590 JLCGNEPB_00005 2985 3 Skin 0.33 protein_coding synonymous_variant LOW 450C>T Thr150Thr
M0056591 JLCGNEPB_00005 3006 3 Skin 0.33 protein_coding synonymous_variant LOW 471C>T Pro157Pro
M0056592 JLCGNEPB_00005 3066 3 Skin 0.33 protein_coding synonymous_variant LOW 531G>A Ala177Ala
M0056593 JLCGNEPB_00005 3072 3 Skin 0.33 protein_coding synonymous_variant LOW 537A>G Ala179Ala
M0056594 JLCGNEPB_00005 3126 3 Skin 0.33 protein_coding synonymous_variant LOW 591G>C Thr197Thr
M0056595 JLCGNEPB_00005 3159 3 Skin 0.33 protein_coding synonymous_variant LOW 624C>T Cys208Cys
M0056596 JLCGNEPB_00005 3210 3 Skin 0.33 protein_coding synonymous_variant LOW 675G>C Val225Val
M0056597 JLCGNEPB_00005 3220 3 Skin 0.33 protein_coding missense_variant MODERATE 685G>C Ala229Pro
M0056598 JLCGNEPB_00005 3240 3 Skin 0.33 protein_coding synonymous_variant LOW 705C>T Leu235Leu
M0056599 JLCGNEPB_00005 3243 3 Skin 0.33 protein_coding synonymous_variant LOW 708G>C Ala236Ala
M0056600 JLCGNEPB_00005 3253 3 Skin 0.33 protein_coding missense_variant MODERATE 718A>G Thr240Ala
M0056601 JLCGNEPB_00005 3256 3 Skin 0.33 protein_coding missense_variant MODERATE 721C>T Pro241Ser
M0056602 JLCGNEPB_00005 3263 3 Skin 0.33 protein_coding missense_variant MODERATE 728A>G Gln243Arg
M0056603 JLCGNEPB_00005 3264 3 Skin 0.33 protein_coding missense_variant MODERATE 729G>C Gln243His
M0056604 JLCGNEPB_00005 3286 3 Skin 0.33 protein_coding missense_variant MODERATE 751C>G Arg251Gly
M0056605 JLCGNEPB_00005 3287 3 Skin 0.33 protein_coding missense_variant MODERATE 752G>C Arg251Pro
M0056606 JLCGNEPB_00005 3291 3 Skin 0.33 protein_coding synonymous_variant LOW 756T>C Val252Val
M0056607 JLCGNEPB_00005 3312 3 Skin 0.33 protein_coding synonymous_variant LOW 777A>C Gly259Gly
M0056608 JLCGNEPB_00005 3315 3 Skin 0.33 protein_coding synonymous_variant LOW 780G>C Ala260Ala
M0056609 JLCGNEPB_00005 3333 3 Skin 0.33 protein_coding synonymous_variant LOW 798T>C Gly266Gly
M0056610 JLCGNEPB_00005 3342 3 Skin 0.33 protein_coding synonymous_variant LOW 807T>C Asn269Asn
M0056611 JLCGNEPB_00005 3396 4 Skin 0.44 protein_coding synonymous_variant LOW 861T>C Ala287Ala
M0056612 JLCGNEPB_00005 3420 4 Skin 0.44 protein_coding synonymous_variant LOW 885C>G Arg295Arg
M0056613 JLCGNEPB_00005 3423 4 Skin 0.44 protein_coding missense_variant MODERATE 888G>T Glu296Asp
M0056614 JLCGNEPB_00005 3429 4 Skin 0.44 protein_coding synonymous_variant LOW 894G>C Leu298Leu
M0056615 JLCGNEPB_00005 3452 4 Skin 0.44 protein_coding missense_variant MODERATE 917A>C Asp306Ala
M0056616 JLCGNEPB_00005 3457 4 Skin 0.44 protein_coding missense_variant MODERATE 922A>C Met308Leu
M0056617 JLCGNEPB_00005 3485 4 Skin 0.44 protein_coding missense_variant MODERATE 950A>T Tyr317Phe
M0056618 JLCGNEPB_00005 3492 4 Skin 0.44 protein_coding synonymous_variant LOW 957T>C Asp319Asp
M0056619 JLCGNEPB_00005 3504 4 Skin 0.44 protein_coding synonymous_variant LOW 969C>T Asp323Asp
M0056620 JLCGNEPB_00006 3709 5 Skin 0.56 protein_coding synonymous_variant LOW 153T>C Thr51Thr
M0056621 JLCGNEPB_00006 3712 5 Skin 0.56 protein_coding synonymous_variant LOW 156C>G Ala52Ala
M0056622 JLCGNEPB_00006 3733 5 Skin 0.56 protein_coding synonymous_variant LOW 177A>G Ala59Ala
M0056623 JLCGNEPB_00006 3748 5 Skin 0.56 protein_coding synonymous_variant LOW 192G>T Leu64Leu
M0056624 JLCGNEPB_00006 3754 5 Skin 0.56 protein_coding synonymous_variant LOW 198T>G Leu66Leu
M0056625 JLCGNEPB_00006 3772 5 Skin 0.56 protein_coding synonymous_variant LOW 216C>G Leu72Leu
M0056626 JLCGNEPB_00006 3958 6 Skin 0.67 protein_coding synonymous_variant LOW 402T>C Cys134Cys
M0056627 JLCGNEPB_00006 3988 5 Skin 0.56 protein_coding synonymous_variant LOW 432A>G Gly144Gly
M0056628 JLCGNEPB_00006 4018 5 Skin 0.56 protein_coding synonymous_variant LOW 462G>A Ala154Ala
M0056629 JLCGNEPB_00006 4948 5 Skin 0.56 protein_coding synonymous_variant LOW 1392T>C Gly464Gly
M0056630 JLCGNEPB_00006 5119 5 Skin 0.56 protein_coding synonymous_variant LOW 1563G>C Pro521Pro
M0056631 JLCGNEPB_00006 5146 5 Skin 0.56 protein_coding synonymous_variant LOW 1590G>C Pro530Pro
M0056632 JLCGNEPB_00006 5197 5 Skin 0.56 protein_coding synonymous_variant LOW 1641G>C Pro547Pro
M0056633 JLCGNEPB_00006 5200 5 Skin 0.56 protein_coding synonymous_variant LOW 1644G>C Leu548Leu
M0056634 JLCGNEPB_00006 5236 5 Skin 0.56 protein_coding synonymous_variant LOW 1680C>T Asp560Asp
M0056635 JLCGNEPB_00006 5254 5 Skin 0.56 protein_coding synonymous_variant LOW 1698C>A Ala566Ala
M0056636 JLCGNEPB_00006 5266 5 Skin 0.56 protein_coding synonymous_variant LOW 1710G>A Glu570Glu
M0056637 JLCGNEPB_00006 5299 5 Skin 0.56 protein_coding synonymous_variant LOW 1743G>T Leu581Leu
M0056638 JLCGNEPB_00006 5305 5 Skin 0.56 protein_coding synonymous_variant LOW 1749C>G Gly583Gly
M0056639 JLCGNEPB_00006 5605 5 Skin 0.56 protein_coding synonymous_variant LOW 2049C>G Leu683Leu
M0056640 JLCGNEPB_00006 5905 5 Skin 0.56 protein_coding synonymous_variant LOW 2349T>C Val783Val
M0056641 JLCGNEPB_00006 5946 5 Skin 0.56 protein_coding missense_variant MODERATE 2390C>T Ala797Val
M0056642 JLCGNEPB_00006 5965 5 Skin 0.56 protein_coding synonymous_variant LOW 2409G>C Gly803Gly
M0056643 JLCGNEPB_00006 5969 5 Skin 0.56 protein_coding missense_variant MODERATE 2413G>A Gly805Ser
M0056644 JLCGNEPB_00006 6004 6 Skin 0.67 protein_coding synonymous_variant LOW 2448C>T Asp816Asp
M0056645 JLCGNEPB_00006 6016 6 Skin 0.67 protein_coding synonymous_variant LOW 2460G>C Val820Val
M0056646 JLCGNEPB_00006 6017 6 Skin 0.67 protein_coding missense_variant MODERATE 2461G>A Ala821Thr
M0056647 JLCGNEPB_00007 6387 6 Skin 0.67 protein_coding synonymous_variant LOW 288T>C Leu96Leu
M0056648 JLCGNEPB_00008 6765 5 Skin 0.56 protein_coding missense_variant MODERATE 298T>C Phe100Leu
M0056649 JLCGNEPB_00009 7282 4 Skin 0.44 protein_coding missense_variant MODERATE 529A>G Met177Val
M0056650 JLCGNEPB_00009 7309 4 Skin 0.44 protein_coding missense_variant MODERATE 502A>G Met168Val
M0056651 JLCGNEPB_00009 7375 5 Skin 0.56 protein_coding missense_variant MODERATE 436A>G Arg146Gly
M0056652 JLCGNEPB_00009 7468 5 Skin 0.56 protein_coding missense_variant MODERATE 343C>A Pro115Thr
M0056653 JLCGNEPB_00009 7469 5 Skin 0.56 protein_coding synonymous_variant LOW 342G>T Leu114Leu
M0056654 JLCGNEPB_00006 4873 4 Skin 0.44 protein_coding synonymous_variant LOW 1317C>G Gly439Gly
M0056655 JLCGNEPB_00006 4903 4 Skin 0.44 protein_coding synonymous_variant LOW 1347T>C Gly449Gly
M0056656 JLCGNEPB_00006 5029 4 Skin 0.44 protein_coding synonymous_variant LOW 1473A>G Ala491Ala
M0056657 JLCGNEPB_00006 5677 4 Skin 0.44 protein_coding synonymous_variant LOW 2121G>T Pro707Pro
M0056658 JLCGNEPB_00006 5682 4 Skin 0.44 protein_coding missense_variant MODERATE 2126G>C Gly709Ala
M0056659 JLCGNEPB_00006 5696 4 Skin 0.44 protein_coding missense_variant MODERATE 2140G>C Gly714Arg
M0056660 JLCGNEPB_00006 5697 4 Skin 0.44 protein_coding missense_variant MODERATE 2141G>T Gly714Val
M0056661 JLCGNEPB_00006 5698 4 Skin 0.44 protein_coding synonymous_variant LOW 2142A>G Gly714Gly
M0056662 JLCGNEPB_00006 5768 4 Skin 0.44 protein_coding missense_variant MODERATE 2212C>A Arg738Ser
M0056663 JLCGNEPB_00006 5770 4 Skin 0.44 protein_coding synonymous_variant LOW 2214C>G Arg738Arg
M0056664 JLCGNEPB_00006 5771 4 Skin 0.44 protein_coding missense_variant MODERATE 2215G>A Val739Ile
M0056665 JLCGNEPB_00006 5803 4 Skin 0.44 protein_coding synonymous_variant LOW 2247T>C Val749Val
M0056666 JLCGNEPB_00006 5835 4 Skin 0.44 protein_coding missense_variant MODERATE 2279T>C Val760Ala
M0056667 JLCGNEPB_00007 6132 5 Skin 0.56 protein_coding synonymous_variant LOW 33C>T Gly11Gly
M0056668 JLCGNEPB_00007 6229 5 Skin 0.56 protein_coding missense_variant MODERATE 130A>G Lys44Glu
M0056669 JLCGNEPB_00007 6239 4 Skin 0.44 protein_coding missense_variant MODERATE 140C>G Thr47Arg
M0056670 JLCGNEPB_00007 6258 4 Skin 0.44 protein_coding synonymous_variant LOW 159C>G Ala53Ala
M0056671 JLCGNEPB_00007 6279 4 Skin 0.44 protein_coding synonymous_variant LOW 180G>T Leu60Leu
M0056672 JLCGNEPB_00007 6284 4 Skin 0.44 protein_coding missense_variant MODERATE 185C>T Ala62Val
M0056673 JLCGNEPB_00008 6488 5 Skin 0.56 protein_coding synonymous_variant LOW 21C>T Leu7Leu
M0056674 JLCGNEPB_00008 6620 4 Skin 0.44 protein_coding synonymous_variant LOW 153A>G Ala51Ala
M0056675 JLCGNEPB_00008 6634 4 Skin 0.44 protein_coding missense_variant MODERATE 167C>G Ala56Gly
M0056676 JLCGNEPB_00008 6665 4 Skin 0.44 protein_coding synonymous_variant LOW 198T>C Gly66Gly
M0056677 JLCGNEPB_00008 6669 3 Skin 0.33 protein_coding missense_variant MODERATE 202G>A Val68Ile
M0056678 JLCGNEPB_00008 6671 4 Skin 0.44 protein_coding synonymous_variant LOW 204A>G Val68Val
M0056679 JLCGNEPB_00008 6675 4 Skin 0.44 protein_coding missense_variant MODERATE 208C>T Leu70Phe
M0056680 JLCGNEPB_00008 6677 3 Skin 0.33 protein_coding synonymous_variant LOW 210T>G Leu70Leu
M0056681 JLCGNEPB_00008 6866 3 Skin 0.33 protein_coding synonymous_variant LOW 399C>T Gly133Gly
M0056682 JLCGNEPB_00008 6902 4 Skin 0.44 protein_coding synonymous_variant LOW 435A>C Gly145Gly
M0056683 JLCGNEPB_00008 6903 4 Skin 0.44 protein_coding missense_variant MODERATE 436G>A Val146Ile
M0056684 JLCGNEPB_00009 7078 3 Skin 0.33 protein_coding missense_variant MODERATE 733C>T Arg245Cys
M0056685 JLCGNEPB_00009 7092 3 Skin 0.33 protein_coding missense_variant MODERATE 719G>C Gly240Ala
M0056686 JLCGNEPB_00009 7870 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -60T>C None
M0056687 JLCGNEPB_00009 7882 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -72C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term