Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2777
  Reference Plasmid   1111525849862995_bin.12_new__k141_16020
  Reference Plasmid Size   4336
  Reference Plasmid GC Content   0.72
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056688 LMPFAOIO_00001 675 8 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *86T>G None
M0056689 LMPFAOIO_00001 679 8 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *90G>A None
M0056690 LMPFAOIO_00001 685 8 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *96G>T None
M0056691 LMPFAOIO_00001 687 8 Skin 0.80 protein_coding downstream_gene_variant MODIFIER *98G>A None
M0056692 LMPFAOIO_00002 702 8 Skin 0.80 protein_coding missense_variant MODERATE 1322T>C Val441Ala
M0056693 LMPFAOIO_00002 704 8 Skin 0.80 protein_coding synonymous_variant LOW 1320C>G Ala440Ala
M0056694 LMPFAOIO_00002 710 8 Skin 0.80 protein_coding synonymous_variant LOW 1314G>C Pro438Pro
M0056695 LMPFAOIO_00002 720 8 Skin 0.80 protein_coding missense_variant MODERATE 1304C>G Ala435Gly
M0056696 LMPFAOIO_00002 731 8 Skin 0.80 protein_coding synonymous_variant LOW 1293A>G Glu431Glu
M0056697 LMPFAOIO_00002 803 8 Skin 0.80 protein_coding missense_variant MODERATE 1221C>G Asp407Glu
M0056698 LMPFAOIO_00002 806 8 Skin 0.80 protein_coding synonymous_variant LOW 1218T>C Ala406Ala
M0056699 LMPFAOIO_00002 830 8 Skin 0.80 protein_coding synonymous_variant LOW 1194T>C Asn398Asn
M0056700 LMPFAOIO_00002 859 8 Skin 0.80 protein_coding synonymous_variant LOW 1165T>C Leu389Leu
M0056701 LMPFAOIO_00002 887 8 Skin 0.80 protein_coding synonymous_variant LOW 1137G>A Gly379Gly
M0056702 LMPFAOIO_00002 911 8 Skin 0.80 protein_coding synonymous_variant LOW 1113T>C Phe371Phe
M0056703 LMPFAOIO_00002 932 8 Skin 0.80 protein_coding synonymous_variant LOW 1092G>C Thr364Thr
M0056704 LMPFAOIO_00002 955 8 Skin 0.80 protein_coding missense_variant MODERATE 1069G>A Ala357Thr
M0056705 LMPFAOIO_00002 977 8 Skin 0.80 protein_coding synonymous_variant LOW 1047A>G Ala349Ala
M0056706 LMPFAOIO_00002 1025 8 Skin 0.80 protein_coding synonymous_variant LOW 999G>C Thr333Thr
M0056707 LMPFAOIO_00002 1040 8 Skin 0.80 protein_coding synonymous_variant LOW 984C>G Thr328Thr
M0056708 LMPFAOIO_00002 1073 8 Skin 0.80 protein_coding synonymous_variant LOW 951C>G Val317Val
M0056709 LMPFAOIO_00002 1097 8 Skin 0.80 protein_coding synonymous_variant LOW 927C>T Val309Val
M0056710 LMPFAOIO_00002 1180 8 Skin 0.80 protein_coding synonymous_variant LOW 844C>T Leu282Leu
M0056711 LMPFAOIO_00002 1292 8 Skin 0.80 protein_coding synonymous_variant LOW 732C>G Leu244Leu
M0056712 LMPFAOIO_00002 1301 8 Skin 0.80 protein_coding synonymous_variant LOW 723A>G Glu241Glu
M0056713 LMPFAOIO_00002 1355 8 Skin 0.80 protein_coding missense_variant MODERATE 669C>G Ile223Met
M0056714 LMPFAOIO_00002 1406 8 Skin 0.80 protein_coding synonymous_variant LOW 618G>T Val206Val
M0056715 LMPFAOIO_00002 1415 8 Skin 0.80 protein_coding synonymous_variant LOW 609C>A Arg203Arg
M0056716 LMPFAOIO_00002 1502 7 Skin 0.70 protein_coding synonymous_variant LOW 522C>T Tyr174Tyr
M0056717 LMPFAOIO_00002 1516 8 Skin 0.80 protein_coding missense_variant MODERATE 508A>G Ser170Gly
M0056718 LMPFAOIO_00002 1619 5 Skin 0.50 protein_coding synonymous_variant LOW 405G>C Ala135Ala
M0056719 LMPFAOIO_00002 1664 7 Skin 0.70 protein_coding synonymous_variant LOW 360G>T Ser120Ser
M0056720 LMPFAOIO_00002 1712 8 Skin 0.80 protein_coding synonymous_variant LOW 312C>T Asp104Asp
M0056721 LMPFAOIO_00002 1724 8 Skin 0.80 protein_coding synonymous_variant LOW 300C>T Asp100Asp
M0056722 LMPFAOIO_00002 1727 8 Skin 0.80 protein_coding synonymous_variant LOW 297C>T Phe99Phe
M0056723 LMPFAOIO_00002 1730 8 Skin 0.80 protein_coding synonymous_variant LOW 294T>C Gly98Gly
M0056724 LMPFAOIO_00002 1761 8 Skin 0.80 protein_coding missense_variant MODERATE 263G>A Gly88Glu
M0056725 LMPFAOIO_00002 1769 7 Skin 0.70 protein_coding synonymous_variant LOW 255C>T Ala85Ala
M0056726 LMPFAOIO_00002 1817 8 Skin 0.80 protein_coding synonymous_variant LOW 207T>G Leu69Leu
M0056727 LMPFAOIO_00002 1841 8 Skin 0.80 protein_coding synonymous_variant LOW 183C>G Pro61Pro
M0056728 LMPFAOIO_00002 1843 7 Skin 0.70 protein_coding missense_variant MODERATE 181C>G Pro61Ala
M0056729 LMPFAOIO_00002 1925 7 Skin 0.70 protein_coding synonymous_variant LOW 99G>C Leu33Leu
M0056730 LMPFAOIO_00002 1936 7 Skin 0.70 protein_coding missense_variant MODERATE 88G>C Ala30Pro
M0056731 LMPFAOIO_00002 1940 7 Skin 0.70 protein_coding synonymous_variant LOW 84A>G Gln28Gln
M0056732 LMPFAOIO_00002 1943 7 Skin 0.70 protein_coding synonymous_variant LOW 81G>A Val27Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term