Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2778
  Reference Plasmid   1111525849862995_bin.15__k141_128585
  Reference Plasmid Size   24988
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056733 INGKLNHB_00017 15508 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -916T>C None
M0056734 INGKLNHB_00017 15899 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -1307C>G None
M0056735 INGKLNHB_00017 16090 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -1498G>C None
M0056736 INGKLNHB_00019 16440 3 Skin 0.30 protein_coding synonymous_variant LOW 582T>G Val194Val
M0056737 INGKLNHB_00019 16623 3 Skin 0.30 protein_coding synonymous_variant LOW 399A>G Pro133Pro
M0056738 INGKLNHB_00021 19192 4 Skin 0.40 protein_coding missense_variant MODERATE 410G>A Gly137Asp
M0056739 INGKLNHB_00018 19697 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4218C>G None
M0056740 INGKLNHB_00018 19719 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4240A>C None
M0056741 INGKLNHB_00018 19729 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4250G>A None
M0056742 INGKLNHB_00022 20044 4 Skin 0.40 protein_coding synonymous_variant LOW 501G>A Thr167Thr
M0056743 INGKLNHB_00022 20134 3 Skin 0.30 protein_coding synonymous_variant LOW 411G>A Glu137Glu
M0056744 INGKLNHB_00022 20144 3 Skin 0.30 protein_coding missense_variant MODERATE 401A>C Glu134Ala
M0056745 INGKLNHB_00022 20148 3 Skin 0.30 protein_coding missense_variant MODERATE 397G>C Ala133Pro
M0056746 INGKLNHB_00022 20164 3 Skin 0.30 protein_coding synonymous_variant LOW 381T>C Ser127Ser
M0056747 INGKLNHB_00022 20200 3 Skin 0.30 protein_coding synonymous_variant LOW 345G>A Lys115Lys
M0056748 INGKLNHB_00022 20213 4 Skin 0.40 protein_coding missense_variant MODERATE 332G>C Arg111Pro
M0056749 INGKLNHB_00022 20220 4 Skin 0.40 protein_coding missense_variant MODERATE 325A>G Ser109Gly
M0056750 INGKLNHB_00022 20324 3 Skin 0.30 protein_coding missense_variant MODERATE 221A>G His74Arg
M0056751 INGKLNHB_00023 21476 4 Skin 0.40 protein_coding synonymous_variant LOW 84A>G Ser28Ser
M0056752 INGKLNHB_00024 21909 4 Skin 0.40 protein_coding missense_variant MODERATE 233A>C Tyr78Ser
M0056753 INGKLNHB_00024 21920 4 Skin 0.40 protein_coding synonymous_variant LOW 222T>G Thr74Thr
M0056754 INGKLNHB_00008 12006 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4277G>C None
M0056755 INGKLNHB_00015 12755 3 Skin 0.30 protein_coding missense_variant MODERATE 14T>C Leu5Pro
M0056756 INGKLNHB_00016 13400 3 Skin 0.30 protein_coding synonymous_variant LOW 60A>G Ser20Ser
M0056757 INGKLNHB_00017 14333 3 Skin 0.30 protein_coding missense_variant MODERATE 260G>A Gly87Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term