Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2781
  Reference Plasmid   1111525849862995_bin.15__k141_211980
  Reference Plasmid Size   11890
  Reference Plasmid GC Content   0.71
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056807 IJOJPKMO_00003 2188 3 Skin 0.43 protein_coding missense_variant MODERATE 175C>A Leu59Met
M0056808 IJOJPKMO_00003 2208 3 Skin 0.43 protein_coding synonymous_variant LOW 195A>C Gly65Gly
M0056809 IJOJPKMO_00006 5902 3 Skin 0.43 protein_coding missense_variant MODERATE 615G>C Glu205Asp
M0056810 IJOJPKMO_00006 5908 3 Skin 0.43 protein_coding synonymous_variant LOW 621T>G Leu207Leu
M0056811 IJOJPKMO_00006 5914 3 Skin 0.43 protein_coding synonymous_variant LOW 627C>G Ala209Ala
M0056812 IJOJPKMO_00006 5915 3 Skin 0.43 protein_coding synonymous_variant LOW 628C>A Arg210Arg
M0056813 IJOJPKMO_00006 5916 3 Skin 0.43 protein_coding missense_variant MODERATE 629G>A Arg210Gln
M0056814 IJOJPKMO_00006 5926 3 Skin 0.43 protein_coding synonymous_variant LOW 639G>C Ala213Ala
M0056815 IJOJPKMO_00006 5927 3 Skin 0.43 protein_coding missense_variant MODERATE 640A>C Lys214Gln
M0056816 IJOJPKMO_00006 5928 3 Skin 0.43 protein_coding missense_variant MODERATE 641A>G Lys214Arg
M0056817 IJOJPKMO_00006 5936 3 Skin 0.43 protein_coding synonymous_variant LOW 649A>C Arg217Arg
M0056818 IJOJPKMO_00006 5937 3 Skin 0.43 protein_coding missense_variant MODERATE 650G>A Arg217Lys
M0056819 IJOJPKMO_00007 6741 3 Skin 0.43 protein_coding synonymous_variant LOW 780A>G Ala260Ala
M0056820 IJOJPKMO_00008 7228 3 Skin 0.43 protein_coding missense_variant MODERATE 31G>A Val11Ile
M0056821 IJOJPKMO_00008 7371 3 Skin 0.43 protein_coding synonymous_variant LOW 174G>C Ser58Ser
M0056822 IJOJPKMO_00008 7437 3 Skin 0.43 protein_coding synonymous_variant LOW 240T>C Ile80Ile
M0056823 IJOJPKMO_00008 7689 3 Skin 0.43 protein_coding synonymous_variant LOW 492A>G Pro164Pro
M0056824 IJOJPKMO_00008 7737 3 Skin 0.43 protein_coding synonymous_variant LOW 540C>G Ala180Ala
M0056825 IJOJPKMO_00008 7739 3 Skin 0.43 protein_coding missense_variant MODERATE 542G>A Arg181Lys
M0056826 IJOJPKMO_00009 8296 4 Skin 0.57 protein_coding synonymous_variant LOW 222A>G Glu74Glu
M0056827 IJOJPKMO_00009 8297 4 Skin 0.57 protein_coding missense_variant MODERATE 223T>G Ser75Ala
M0056828 IJOJPKMO_00009 8910 3 Skin 0.43 protein_coding missense_variant MODERATE 836C>A Ala279Asp
M0056829 IJOJPKMO_00009 9522 3 Skin 0.43 protein_coding missense_variant MODERATE 1448T>C Phe483Ser
M0056830 IJOJPKMO_00009 9532 3 Skin 0.43 protein_coding synonymous_variant LOW 1458G>C Gly486Gly
M0056831 IJOJPKMO_00010 10061 3 Skin 0.43 protein_coding synonymous_variant LOW 33C>T Ala11Ala
M0056832 IJOJPKMO_00010 11128 3 Skin 0.43 protein_coding missense_variant MODERATE 1100T>G Leu367Arg
M0056833 IJOJPKMO_00010 11536 3 Skin 0.43 protein_coding missense_variant MODERATE 1508G>C Arg503Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term