Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2784
  Reference Plasmid   1111525849862995_bin.15__k141_356747
  Reference Plasmid Size   21415
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056867 ABFKLECE_00007 7128 4 Skin 0.44 protein_coding synonymous_variant LOW 1236T>C Gly412Gly
M0056868 ABFKLECE_00007 7149 4 Skin 0.44 protein_coding synonymous_variant LOW 1215G>A Ala405Ala
M0056869 ABFKLECE_00007 7197 4 Skin 0.44 protein_coding synonymous_variant LOW 1167G>C Ser389Ser
M0056870 ABFKLECE_00007 7218 3 Skin 0.33 protein_coding synonymous_variant LOW 1146G>A Val382Val
M0056871 ABFKLECE_00008 9152 4 Skin 0.44 protein_coding synonymous_variant LOW 486T>C Asp162Asp
M0056872 ABFKLECE_00008 9160 4 Skin 0.44 protein_coding missense_variant MODERATE 494A>G Gln165Arg
M0056873 ABFKLECE_00008 9166 4 Skin 0.44 protein_coding missense_variant MODERATE 500G>C Ser167Thr
M0056874 ABFKLECE_00008 9167 4 Skin 0.44 protein_coding synonymous_variant LOW 501T>C Ser167Ser
M0056875 ABFKLECE_00008 9171 4 Skin 0.44 protein_coding missense_variant MODERATE 505T>G Ser169Ala
M0056876 ABFKLECE_00008 9182 4 Skin 0.44 protein_coding synonymous_variant LOW 516C>G Val172Val
M0056877 ABFKLECE_00008 9191 4 Skin 0.44 protein_coding synonymous_variant LOW 525T>C Asp175Asp
M0056878 ABFKLECE_00008 9213 4 Skin 0.44 protein_coding missense_variant MODERATE 547T>G Ser183Ala
M0056879 ABFKLECE_00008 9227 4 Skin 0.44 protein_coding synonymous_variant LOW 561C>G Gly187Gly
M0056880 ABFKLECE_00008 9233 4 Skin 0.44 protein_coding synonymous_variant LOW 567A>G Glu189Glu
M0056881 ABFKLECE_00008 9239 4 Skin 0.44 protein_coding synonymous_variant LOW 573T>G Pro191Pro
M0056882 ABFKLECE_00008 9254 4 Skin 0.44 protein_coding synonymous_variant LOW 588C>G Val196Val
M0056883 ABFKLECE_00008 9284 4 Skin 0.44 protein_coding missense_variant MODERATE 618C>A Asp206Glu
M0056884 ABFKLECE_00008 9302 4 Skin 0.44 protein_coding synonymous_variant LOW 636C>G Gly212Gly
M0056885 ABFKLECE_00007 12949 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4586T>C None
M0056886 ABFKLECE_00007 12950 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4587G>C None
M0056887 ABFKLECE_00007 12983 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4620G>A None
M0056888 ABFKLECE_00013 16695 4 Skin 0.44 protein_coding synonymous_variant LOW 1167T>C Leu389Leu
M0056889 ABFKLECE_00015 18402 3 Skin 0.33 protein_coding synonymous_variant LOW 759C>T Gly253Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term