Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2785
  Reference Plasmid   1111525849862995_bin.15__k141_382057
  Reference Plasmid Size   19718
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0056890 AMDNBCKA_00015 17980 5 Skin 0.31 protein_coding missense_variant MODERATE 482A>G Gln161Arg
M0056891 AMDNBCKA_00012 19618 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4198T>C None
M0056892 AMDNBCKA_00012 19657 4 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -4237C>A None
M0056893 AMDNBCKA_00005 7666 3 Skin 0.19 protein_coding synonymous_variant LOW 570C>T Ser190Ser
M0056894 AMDNBCKA_00006 7913 3 Skin 0.19 protein_coding missense_variant MODERATE 1003A>G Lys335Glu
M0056895 AMDNBCKA_00006 8490 3 Skin 0.19 protein_coding synonymous_variant LOW 426T>C Ser142Ser
M0056896 AMDNBCKA_00006 8836 4 Skin 0.25 protein_coding missense_variant MODERATE 80T>C Leu27Pro
M0056897 AMDNBCKA_00006 8922 3 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -7T>C None
M0056898 AMDNBCKA_00009 11421 3 Skin 0.19 protein_coding synonymous_variant LOW 1113T>C Pro371Pro
M0056899 AMDNBCKA_00009 11979 5 Skin 0.31 protein_coding synonymous_variant LOW 555T>C Leu185Leu
M0056900 AMDNBCKA_00009 12444 3 Skin 0.19 protein_coding synonymous_variant LOW 90C>T Arg30Arg
M0056901 AMDNBCKA_00010 12784 5 Skin 0.31 protein_coding synonymous_variant LOW 846C>G Leu282Leu
M0056902 AMDNBCKA_00010 12787 5 Skin 0.31 protein_coding synonymous_variant LOW 843C>T His281His
M0056903 AMDNBCKA_00010 12793 5 Skin 0.31 protein_coding synonymous_variant LOW 837G>C Pro279Pro
M0056904 AMDNBCKA_00010 12798 5 Skin 0.31 protein_coding synonymous_variant LOW 832A>C Arg278Arg
M0056905 AMDNBCKA_00010 12802 5 Skin 0.31 protein_coding synonymous_variant LOW 828G>C Gly276Gly
M0056906 AMDNBCKA_00010 13213 3 Skin 0.19 protein_coding synonymous_variant LOW 417C>T Arg139Arg
M0056907 AMDNBCKA_00011 14208 3 Skin 0.19 protein_coding synonymous_variant LOW 285C>T Asn95Asn
M0056908 AMDNBCKA_00015 18590 3 Skin 0.19 protein_coding synonymous_variant LOW 1092T>C Gly364Gly
M0056909 AMDNBCKA_00002 3570 5 Skin 0.31 protein_coding synonymous_variant LOW 1797A>G Gln599Gln
M0056910 AMDNBCKA_00007 9035 3 Skin 0.19 protein_coding synonymous_variant LOW 945C>T Asp315Asp
M0056911 AMDNBCKA_00007 9038 4 Skin 0.25 protein_coding synonymous_variant LOW 942T>C Asn314Asn
M0056912 AMDNBCKA_00014 17257 3 Skin 0.19 protein_coding synonymous_variant LOW 918T>C Ser306Ser
M0056913 AMDNBCKA_00002 3507 4 Skin 0.25 protein_coding synonymous_variant LOW 1734C>A Ala578Ala
M0056914 AMDNBCKA_00003 4259 3 Skin 0.19 protein_coding synonymous_variant LOW 402T>C Asn134Asn
M0056915 AMDNBCKA_00003 4337 3 Skin 0.19 protein_coding synonymous_variant LOW 480T>C Arg160Arg
M0056916 AMDNBCKA_00003 4367 3 Skin 0.19 protein_coding synonymous_variant LOW 510T>C Asp170Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term