Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2794
  Reference Plasmid   1111525849863945_bin.28__k141_285736
  Reference Plasmid Size   5093
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0057090 JAPMJIMD_00001 366 5 Skin 0.50 protein_coding stop_lost&splice_region_variant HIGH 421T>C Ter141Glnext*?
M0057091 JAPMJIMD_00001 388 5 Skin 0.50 protein_coding synonymous_variant LOW 399A>G Val133Val
M0057092 JAPMJIMD_00001 725 3 Skin 0.30 protein_coding missense_variant MODERATE 62C>T Ser21Leu
M0057093 JAPMJIMD_00001 1110 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -324A>C None
M0057094 JAPMJIMD_00001 1507 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -721G>A None
M0057095 JAPMJIMD_00001 1555 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -769T>C None
M0057096 JAPMJIMD_00001 1566 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -780A>G None
M0057097 JAPMJIMD_00001 1567 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -781C>T None
M0057098 JAPMJIMD_00001 1603 5 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -817G>A None
M0057099 JAPMJIMD_00003 2113 5 Skin 0.50 protein_coding missense_variant MODERATE 410A>G Asp137Gly
M0057100 JAPMJIMD_00001 1642 4 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -856T>G None
M0057101 JAPMJIMD_00003 2811 3 Skin 0.30 protein_coding missense_variant MODERATE 1108T>G Phe370Val
M0057102 JAPMJIMD_00003 2868 3 Skin 0.30 protein_coding missense_variant MODERATE 1165A>G Asn389Asp
M0057103 JAPMJIMD_00003 2871 3 Skin 0.30 protein_coding missense_variant MODERATE 1168G>C Glu390Gln
M0057104 JAPMJIMD_00003 2875 3 Skin 0.30 protein_coding missense_variant MODERATE 1172A>G His391Arg
M0057105 JAPMJIMD_00004 3945 3 Skin 0.30 protein_coding synonymous_variant LOW 828A>G Gly276Gly
M0057106 JAPMJIMD_00004 4176 3 Skin 0.30 protein_coding synonymous_variant LOW 1059G>A Val353Val
M0057107 JAPMJIMD_00004 4194 3 Skin 0.30 protein_coding synonymous_variant LOW 1077G>A Gly359Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term