Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2795
  Reference Plasmid   1111525849863945_bin.28__k141_500504
  Reference Plasmid Size   9965
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0057108 CELECCFI_00002 713 5 Skin 0.20 protein_coding synonymous_variant LOW 225T>C Ile75Ile
M0057109 CELECCFI_00002 714 5 Skin 0.20 protein_coding missense_variant MODERATE 226C>G Pro76Ala
M0057110 CELECCFI_00002 734 5 Skin 0.20 protein_coding synonymous_variant LOW 246T>C Asn82Asn
M0057111 CELECCFI_00002 737 5 Skin 0.20 protein_coding missense_variant MODERATE 249G>A Met83Ile
M0057112 CELECCFI_00002 738 5 Skin 0.20 protein_coding missense_variant MODERATE 250A>G Arg84Gly
M0057113 CELECCFI_00002 740 5 Skin 0.20 protein_coding synonymous_variant LOW 252A>G Arg84Arg
M0057114 CELECCFI_00002 741 5 Skin 0.20 protein_coding missense_variant MODERATE 253G>C Val85Leu
M0057115 CELECCFI_00002 742 5 Skin 0.20 protein_coding missense_variant MODERATE 254T>C Val85Ala
M0057116 CELECCFI_00002 765 5 Skin 0.20 protein_coding missense_variant MODERATE 277C>T His93Tyr
M0057117 CELECCFI_00002 780 5 Skin 0.20 protein_coding missense_variant MODERATE 292A>G Asn98Asp
M0057118 CELECCFI_00005 3210 6 Skin 0.24 protein_coding synonymous_variant LOW 1803T>C Arg601Arg
M0057119 CELECCFI_00005 4662 13 Skin 0.52 protein_coding synonymous_variant LOW 351T>C Ile117Ile
M0057120 CELECCFI_00006 5201 11 Skin 0.44 protein_coding missense_variant MODERATE 163T>C Phe55Leu
M0057121 CELECCFI_00006 5238 13 Skin 0.52 protein_coding synonymous_variant LOW 126T>C His42His
M0057122 CELECCFI_00004 5487 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -2793A>G None
M0057123 CELECCFI_00004 5653 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2959T>C None
M0057124 CELECCFI_00005 3915 7 Skin 0.28 protein_coding synonymous_variant LOW 1098A>G Leu366Leu
M0057125 CELECCFI_00005 4007 11 Skin 0.44 protein_coding missense_variant MODERATE 1006T>A Ser336Thr
M0057126 CELECCFI_00005 4017 6 Skin 0.24 protein_coding synonymous_variant LOW 996C>T Tyr332Tyr
M0057127 CELECCFI_00005 4083 4 Skin 0.16 protein_coding synonymous_variant LOW 930G>A Val310Val
M0057128 CELECCFI_00005 4581 7 Skin 0.28 protein_coding synonymous_variant LOW 432T>C Arg144Arg
M0057129 CELECCFI_00005 4917 4 Skin 0.16 protein_coding synonymous_variant LOW 96A>G Gly32Gly
M0057130 CELECCFI_00004 5384 13 Skin 0.52 protein_coding upstream_gene_variant MODIFIER -2690A>G None
M0057131 CELECCFI_00004 5553 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -2859C>T None
M0057132 CELECCFI_00004 5573 9 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -2879T>C None
M0057133 CELECCFI_00004 5680 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2986A>T None
M0057134 CELECCFI_00004 5742 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -3048T>C None
M0057135 CELECCFI_00004 5766 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -3072G>C None
M0057136 CELECCFI_00004 5784 9 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -3090T>C None
M0057137 CELECCFI_00004 5809 8 Skin 0.32 protein_coding upstream_gene_variant MODIFIER -3115A>G None
M0057138 CELECCFI_00004 5906 7 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -3212A>G None
M0057139 CELECCFI_00004 6109 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -3415T>C None
M0057140 CELECCFI_00002 860 6 Skin 0.24 protein_coding synonymous_variant LOW 372C>T Tyr124Tyr
M0057141 CELECCFI_00002 872 6 Skin 0.24 protein_coding synonymous_variant LOW 384A>G Glu128Glu
M0057142 CELECCFI_00003 888 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -30T>A None
M0057143 CELECCFI_00003 898 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -20A>G None
M0057144 CELECCFI_00003 901 7 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -17G>A None
M0057145 CELECCFI_00003 952 10 Skin 0.40 protein_coding missense_variant MODERATE 35C>T Ser12Leu
M0057146 CELECCFI_00003 997 10 Skin 0.40 protein_coding missense_variant MODERATE 80T>C Ile27Thr
M0057147 CELECCFI_00003 1001 10 Skin 0.40 protein_coding synonymous_variant LOW 84A>G Lys28Lys
M0057148 CELECCFI_00003 1002 10 Skin 0.40 protein_coding missense_variant MODERATE 85G>T Asp29Tyr
M0057149 CELECCFI_00003 1004 7 Skin 0.28 protein_coding synonymous_variant LOW 87T>C Asp29Asp
M0057150 CELECCFI_00003 1014 7 Skin 0.28 protein_coding missense_variant MODERATE 97A>G Ile33Val
M0057151 CELECCFI_00003 1026 11 Skin 0.44 protein_coding missense_variant MODERATE 109C>A Gln37Lys
M0057152 CELECCFI_00003 1082 4 Skin 0.16 protein_coding synonymous_variant LOW 165C>T Ile55Ile
M0057153 CELECCFI_00003 1097 7 Skin 0.28 protein_coding synonymous_variant LOW 180G>A Lys60Lys
M0057154 CELECCFI_00003 1101 7 Skin 0.28 protein_coding synonymous_variant LOW 184T>C Leu62Leu
M0057155 CELECCFI_00001 1187 11 Skin 0.44 protein_coding downstream_gene_variant MODIFIER *726G>A None
M0057156 CELECCFI_00001 1190 6 Skin 0.24 protein_coding downstream_gene_variant MODIFIER *729A>C None
M0057157 CELECCFI_00001 1220 5 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *759T>C None
M0057158 CELECCFI_00001 1227 5 Skin 0.20 protein_coding downstream_gene_variant MODIFIER *766G>T None
M0057159 CELECCFI_00004 1849 7 Skin 0.28 protein_coding synonymous_variant LOW 846A>G Leu282Leu
M0057160 CELECCFI_00004 2110 11 Skin 0.44 protein_coding synonymous_variant LOW 585T>C Leu195Leu
M0057161 CELECCFI_00005 2852 11 Skin 0.44 protein_coding missense_variant MODERATE 2161T>C Ser721Pro
M0057162 CELECCFI_00005 3459 4 Skin 0.16 protein_coding synonymous_variant LOW 1554A>G Val518Val
M0057163 CELECCFI_00004 5583 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2889T>G None
M0057164 CELECCFI_00002 609 3 Skin 0.12 protein_coding missense_variant MODERATE 121A>G Ile41Val
M0057165 CELECCFI_00002 641 5 Skin 0.20 protein_coding synonymous_variant LOW 153T>C Cys51Cys
M0057166 CELECCFI_00002 798 4 Skin 0.16 protein_coding missense_variant MODERATE 310A>G Lys104Glu
M0057167 CELECCFI_00002 835 4 Skin 0.16 protein_coding missense_variant MODERATE 347T>G Met116Arg
M0057168 CELECCFI_00004 2077 9 Skin 0.36 protein_coding synonymous_variant LOW 618C>T Gly206Gly
M0057169 CELECCFI_00004 2167 9 Skin 0.36 protein_coding synonymous_variant LOW 528T>C Asn176Asn
M0057170 CELECCFI_00004 2311 8 Skin 0.32 protein_coding synonymous_variant LOW 384G>C Val128Val
M0057171 CELECCFI_00004 2312 8 Skin 0.32 protein_coding missense_variant MODERATE 383T>C Val128Ala
M0057172 CELECCFI_00004 2476 10 Skin 0.40 protein_coding synonymous_variant LOW 219G>A Pro73Pro
M0057173 CELECCFI_00004 2541 10 Skin 0.40 protein_coding missense_variant MODERATE 154A>G Ile52Val
M0057174 CELECCFI_00006 5338 4 Skin 0.16 protein_coding missense_variant MODERATE 26C>T Ser9Phe
M0057175 CELECCFI_00002 706 3 Skin 0.12 protein_coding missense_variant MODERATE 218T>C Phe73Ser
M0057176 CELECCFI_00004 1387 3 Skin 0.12 protein_coding missense_variant MODERATE 1308T>G Asn436Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term