Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2796
  Reference Plasmid   1111525849863945_bin.28__k141_582846
  Reference Plasmid Size   4557
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0057177 FHCAFFNA_00001 279 11 Skin 0.52 protein_coding missense_variant MODERATE 34A>G Ser12Gly
M0057178 FHCAFFNA_00001 1148 11 Skin 0.52 protein_coding downstream_gene_variant MODIFIER *333T>C None
M0057179 FHCAFFNA_00001 641 3 Skin 0.14 protein_coding synonymous_variant LOW 396C>T Asn132Asn
M0057180 FHCAFFNA_00001 2829 5 Skin 0.24 protein_coding downstream_gene_variant MODIFIER *2014C>T None
M0057181 FHCAFFNA_00004 4211 6 Skin 0.29 protein_coding synonymous_variant LOW 279A>G Thr93Thr
M0057182 FHCAFFNA_00001 2061 9 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *1246T>C None
M0057183 FHCAFFNA_00001 2248 12 Skin 0.57 protein_coding downstream_gene_variant MODIFIER *1433A>G None
M0057184 FHCAFFNA_00001 2556 9 Skin 0.43 protein_coding downstream_gene_variant MODIFIER *1741T>C None
M0057185 FHCAFFNA_00004 3421 5 Skin 0.24 protein_coding missense_variant MODERATE 1069T>G Trp357Gly
M0057186 FHCAFFNA_00004 3626 4 Skin 0.19 protein_coding synonymous_variant LOW 864C>T Tyr288Tyr
M0057187 FHCAFFNA_00004 3677 3 Skin 0.14 protein_coding synonymous_variant LOW 813T>C His271His
M0057188 FHCAFFNA_00004 3719 5 Skin 0.24 protein_coding synonymous_variant LOW 771T>C His257His
M0057189 FHCAFFNA_00004 4456 5 Skin 0.24 protein_coding synonymous_variant LOW 34T>C Leu12Leu
M0057190 FHCAFFNA_00001 1735 4 Skin 0.19 protein_coding downstream_gene_variant MODIFIER *920C>A None
M0057191 FHCAFFNA_00004 3431 3 Skin 0.14 protein_coding synonymous_variant LOW 1059A>G Ala353Ala
M0057192 FHCAFFNA_00004 3920 3 Skin 0.14 protein_coding synonymous_variant LOW 570C>T Phe190Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term