Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C51
  Reference Plasmid   AP031468.1
  Reference Plasmid Size   27750
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0058617 FCKDJGDM_00018 12060 3 Skin 0.05 protein_coding synonymous_variant LOW 477A>C Gly159Gly
M0058618 FCKDJGDM_00001 2216 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -1419C>A None
M0058619 FCKDJGDM_00001 2241 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -1444C>T None
M0058620 FCKDJGDM_00001 2345 8 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1548T>C None
M0058621 FCKDJGDM_00001 2386 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -1589C>T None
M0058622 FCKDJGDM_00001 2546 7 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -1749C>G None
M0058623 FCKDJGDM_00003 2600 8 Skin 0.14 protein_coding synonymous_variant LOW 48G>T Gly16Gly
M0058624 FCKDJGDM_00003 2781 9 Skin 0.15 protein_coding missense_variant MODERATE 229A>C Thr77Pro
M0058625 FCKDJGDM_00002 233 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -670C>T None
M0058626 FCKDJGDM_00001 366 5 Skin 0.08 protein_coding synonymous_variant LOW 432G>A Glu144Glu
M0058627 FCKDJGDM_00001 447 4 Skin 0.07 protein_coding synonymous_variant LOW 351T>C Ser117Ser
M0058628 FCKDJGDM_00001 615 6 Skin 0.10 protein_coding synonymous_variant LOW 183A>C Ile61Ile
M0058629 FCKDJGDM_00001 886 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -89T>G None
M0058630 FCKDJGDM_00002 1090 6 Skin 0.10 protein_coding missense_variant MODERATE 188C>T Ser63Phe
M0058631 FCKDJGDM_00019 18253 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4796A>T None
M0058632 FCKDJGDM_00029 18308 4 Skin 0.07 protein_coding missense_variant MODERATE 64T>G Leu22Val
M0058633 FCKDJGDM_00022 18621 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2892A>T None
M0058634 FCKDJGDM_00022 18685 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2956A>T None
M0058635 FCKDJGDM_00022 18688 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2959T>A None
M0058636 FCKDJGDM_00022 18784 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3055T>C None
M0058637 FCKDJGDM_00022 18792 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3063A>G None
M0058638 FCKDJGDM_00022 18839 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3110G>A None
M0058639 FCKDJGDM_00022 18869 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3140G>A None
M0058640 FCKDJGDM_00030 19150 5 Skin 0.08 protein_coding missense_variant MODERATE 53A>G Glu18Gly
M0058641 FCKDJGDM_00030 19175 5 Skin 0.08 protein_coding synonymous_variant LOW 78A>G Lys26Lys
M0058642 FCKDJGDM_00030 19215 5 Skin 0.08 protein_coding missense_variant MODERATE 118G>A Asp40Asn
M0058643 FCKDJGDM_00030 19239 5 Skin 0.08 protein_coding missense_variant MODERATE 142A>G Lys48Glu
M0058644 FCKDJGDM_00001 4702 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3905A>G None
M0058645 FCKDJGDM_00004 3416 12 Skin 0.20 protein_coding synonymous_variant LOW 225T>C Gly75Gly
M0058646 FCKDJGDM_00032 21780 3 Skin 0.05 protein_coding missense_variant MODERATE 289A>G Ile97Val
M0058647 FCKDJGDM_00032 21936 3 Skin 0.05 protein_coding missense_variant MODERATE 133A>C Lys45Gln
M0058648 FCKDJGDM_00004 7417 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3777T>C None
M0058649 FCKDJGDM_00004 7420 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3780A>T None
M0058650 FCKDJGDM_00004 7421 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3781A>T None
M0058651 FCKDJGDM_00004 7424 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3784G>A None
M0058652 FCKDJGDM_00004 7478 9 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -3838A>G None
M0058653 FCKDJGDM_00004 7639 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -3999A>G None
M0058654 FCKDJGDM_00004 7644 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4004A>T None
M0058655 FCKDJGDM_00004 7650 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4010C>T None
M0058656 FCKDJGDM_00001 881 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -84T>C None
M0058657 FCKDJGDM_00022 18535 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2806A>G None
M0058658 FCKDJGDM_00009 7057 6 Skin 0.10 protein_coding missense_variant MODERATE 491A>G Lys164Arg
M0058659 FCKDJGDM_00004 6474 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -2834T>A None
M0058660 FCKDJGDM_00004 6513 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -2873C>T None
M0058661 FCKDJGDM_00004 6526 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -2886A>G None
M0058662 FCKDJGDM_00009 6649 5 Skin 0.08 protein_coding missense_variant MODERATE 83A>C Lys28Thr
M0058663 FCKDJGDM_00009 6927 5 Skin 0.08 protein_coding missense_variant MODERATE 361G>T Ala121Ser
M0058664 FCKDJGDM_00011 7578 6 Skin 0.10 protein_coding missense_variant MODERATE 34T>G Tyr12Asp
M0058665 FCKDJGDM_00022 18956 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3227A>G None
M0058666 FCKDJGDM_00005 3972 3 Skin 0.05 protein_coding synonymous_variant LOW 252C>T Ala84Ala
M0058667 FCKDJGDM_00036 24323 3 Skin 0.05 protein_coding synonymous_variant LOW 811C>T Leu271Leu
M0058668 FCKDJGDM_00032 25411 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3343G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term