Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C57
  Reference Plasmid   CP012495.1
  Reference Plasmid Size   52297
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0143173 FBAHBPCB_00004 5311 3 Gut 0.75 protein_coding synonymous_variant LOW 1653A>C Gly551Gly
M0143174 FBAHBPCB_00004 5839 3 Gut 0.75 protein_coding synonymous_variant LOW 1125C>T Tyr375Tyr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FBAHBPCB_00002 VFG000843 Hemolysin 99 3.3e-265 1 479 1.0 1 Exotoxin Hemolysin D experiment
FBAHBPCB_00056 VFG002039 Heat-stable toxin (ST) 90.3 4.5e-33 1 72 1.0 1 Exotoxin heat stable enterotoxin I experiment
FBAHBPCB_00063 VFG000842 Hemolysin 96.4 1.7e-96 1 168 1.0 0.9825 Exotoxin Hemolysin C experiment
FBAHBPCB_00064 VFG000840 Hemolysin 98.3 0 1 998 1.0 1 Exotoxin Hemolysin A experiment
FBAHBPCB_00002 VFG000843 Hemolysin 99 2.5e-264 1 479 1.0 1 Exotoxin Hemolysin D prediction
FBAHBPCB_00004 VFG036030 EspI, SPATE 95.5 0 1 1363 1.0 1 Effector delivery system serine protease autotransporter EspI prediction
FBAHBPCB_00056 VFG002039 Heat-stable toxin (ST) 90.3 3.3e-32 1 72 1.0 1 Exotoxin heat stable enterotoxin I prediction
FBAHBPCB_00063 VFG000842 Hemolysin 96.4 1.3e-95 1 168 1.0 0.9825 Exotoxin Hemolysin C prediction
FBAHBPCB_00064 VFG033890 Hemolysin 98.4 0 1 998 1.0 1 Exotoxin Hemolysin A prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FBAHBPCB_00052 8.B.24.3.1 98.3 1.6e-63 1 117 1.0000 0.8298 8 Accessory Factors Involved in Transport 8.B Ribosomally synthesized protein/peptide toxins/agonists that target channels and carriers 8.B.24 The Colicin Immunity Protein (ColIP) Functional Family
FBAHBPCB_00064 1.C.11.1.6 98.3 0 1 998 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.11 The Pore-forming RTX Toxin (RTX-toxin) Family