Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C59
  Reference Plasmid   CP019598.1
  Reference Plasmid Size   29492
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0058684 PFEBJBFK_00009 6835 4 Skin 0.57 protein_coding synonymous_variant LOW 720G>A Ala240Ala
M0058685 PFEBJBFK_00009 7545 4 Skin 0.57 protein_coding missense_variant MODERATE 10A>C Asn4His
M0058686 PFEBJBFK_00010 7586 4 Skin 0.57 protein_coding synonymous_variant LOW 1404C>T Thr468Thr
M0058687 PFEBJBFK_00010 7604 4 Skin 0.57 protein_coding synonymous_variant LOW 1386C>T Tyr462Tyr
M0058688 PFEBJBFK_00010 7614 4 Skin 0.57 protein_coding missense_variant MODERATE 1376G>A Ser459Asn
M0058689 PFEBJBFK_00010 7658 4 Skin 0.57 protein_coding synonymous_variant LOW 1332C>T Asn444Asn
M0058690 PFEBJBFK_00010 7703 4 Skin 0.57 protein_coding missense_variant MODERATE 1287G>T Glu429Asp
M0058691 PFEBJBFK_00010 7739 4 Skin 0.57 protein_coding synonymous_variant LOW 1251C>T Ser417Ser
M0058692 PFEBJBFK_00010 7778 4 Skin 0.57 protein_coding synonymous_variant LOW 1212C>T Arg404Arg
M0058693 PFEBJBFK_00010 7840 4 Skin 0.57 protein_coding missense_variant MODERATE 1150A>G Thr384Ala
M0058694 PFEBJBFK_00010 7880 4 Skin 0.57 protein_coding synonymous_variant LOW 1110T>C Gly370Gly
M0058695 PFEBJBFK_00010 7961 4 Skin 0.57 protein_coding synonymous_variant LOW 1029T>C Phe343Phe
M0058696 PFEBJBFK_00010 8012 4 Skin 0.57 protein_coding synonymous_variant LOW 978C>T His326His
M0058697 PFEBJBFK_00010 8092 4 Skin 0.57 protein_coding missense_variant MODERATE 898T>C Ser300Pro
M0058698 PFEBJBFK_00010 8126 4 Skin 0.57 protein_coding synonymous_variant LOW 864A>G Glu288Glu
M0058699 PFEBJBFK_00010 8159 4 Skin 0.57 protein_coding synonymous_variant LOW 831G>T Arg277Arg
M0058700 PFEBJBFK_00010 8246 4 Skin 0.57 protein_coding synonymous_variant LOW 744C>T His248His
M0058701 PFEBJBFK_00010 8357 4 Skin 0.57 protein_coding synonymous_variant LOW 633C>T Asn211Asn
M0058702 PFEBJBFK_00010 8375 4 Skin 0.57 protein_coding missense_variant MODERATE 615T>A Asp205Glu
M0058703 PFEBJBFK_00010 8393 4 Skin 0.57 protein_coding synonymous_variant LOW 597C>A Gly199Gly
M0058704 PFEBJBFK_00010 8405 4 Skin 0.57 protein_coding synonymous_variant LOW 585T>C Arg195Arg
M0058705 PFEBJBFK_00010 8438 4 Skin 0.57 protein_coding synonymous_variant LOW 552A>C Pro184Pro
M0058706 PFEBJBFK_00010 8447 4 Skin 0.57 protein_coding synonymous_variant LOW 543C>T Ile181Ile
M0058707 PFEBJBFK_00010 8457 4 Skin 0.57 protein_coding missense_variant MODERATE 533A>C Lys178Thr
M0058708 PFEBJBFK_00010 8633 4 Skin 0.57 protein_coding synonymous_variant LOW 357T>C Tyr119Tyr
M0058709 PFEBJBFK_00010 8636 4 Skin 0.57 protein_coding synonymous_variant LOW 354T>C Ser118Ser
M0058710 PFEBJBFK_00010 8647 4 Skin 0.57 protein_coding missense_variant MODERATE 343T>G Tyr115Asp
M0058711 PFEBJBFK_00010 8657 4 Skin 0.57 protein_coding synonymous_variant LOW 333G>A Glu111Glu
M0058712 PFEBJBFK_00010 8673 4 Skin 0.57 protein_coding missense_variant MODERATE 317C>T Ala106Val
M0058713 PFEBJBFK_00010 8690 4 Skin 0.57 protein_coding synonymous_variant LOW 300G>A Thr100Thr
M0058714 PFEBJBFK_00010 8722 4 Skin 0.57 protein_coding missense_variant MODERATE 268G>T Ala90Ser
M0058715 PFEBJBFK_00010 8741 4 Skin 0.57 protein_coding synonymous_variant LOW 249A>T Ile83Ile
M0058716 PFEBJBFK_00010 8755 4 Skin 0.57 protein_coding missense_variant MODERATE 235A>G Lys79Glu
M0058717 PFEBJBFK_00010 8765 4 Skin 0.57 protein_coding missense_variant MODERATE 225G>T Glu75Asp
M0058718 PFEBJBFK_00010 8807 4 Skin 0.57 protein_coding synonymous_variant LOW 183T>G Gly61Gly
M0058719 PFEBJBFK_00010 8812 4 Skin 0.57 protein_coding missense_variant MODERATE 178C>G Gln60Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
PFEBJBFK_00015 ARO:3008823 100 1.9e-196 1 281 1.0000 1.0000 penicillin beta-lactam BlaZ beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term