Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2
  Reference Plasmid   CP030482.1
  Reference Plasmid Size   23551
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0058727 FCAKBLPA_00021 13925 10 Skin 0.53 protein_coding missense_variant MODERATE 133T>C Ser45Pro
M0058728 FCAKBLPA_00016 11751 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -641G>A None
M0058729 FCAKBLPA_00016 11766 5 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -656C>T None
M0058730 FCAKBLPA_00021 14462 3 Skin 0.16 protein_coding missense_variant MODERATE 670G>T Ala224Ser
M0058731 FCAKBLPA_00016 11077 3 Skin 0.16 protein_coding missense_variant MODERATE 34G>A Val12Ile
M0058732 FCAKBLPA_00017 11532 4 Skin 0.21 protein_coding missense_variant MODERATE 116A>G Glu39Gly
M0058733 FCAKBLPA_00024 16993 3 Skin 0.16 protein_coding missense_variant MODERATE 712T>G Ser238Ala
M0058734 FCAKBLPA_00024 17376 3 Skin 0.16 protein_coding synonymous_variant LOW 1095G>A Lys365Lys
M0058735 FCAKBLPA_00024 17415 3 Skin 0.16 protein_coding synonymous_variant LOW 1134T>A Pro378Pro
M0058736 FCAKBLPA_00016 11044 3 Skin 0.16 protein_coding missense_variant MODERATE 67G>A Val23Met
M0058737 FCAKBLPA_00016 11088 3 Skin 0.16 protein_coding missense_variant MODERATE 23G>T Trp8Leu
M0143641 HHJIKCPJ_00021 13925 5 Gut 0.71 protein_coding missense_variant MODERATE 133T>C Ser45Pro
M0143642 HHJIKCPJ_00021 13862 3 Gut 0.43 protein_coding missense_variant MODERATE 70G>T Ala24Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
FCAKBLPA_00014 Triclosan [class: Phenolic compounds] 99.2 1e-140 1 256 1.0000 1.0000 experiment
HHJIKCPJ_00014 Triclosan [class: Phenolic compounds] 99.2 1e-140 1 256 1.0000 1.0000 experiment
FCAKBLPA_00014 Triclosan [class: Phenolic compounds] 100 1.7e-139 1 256 1.0000 1.0000 prediction
HHJIKCPJ_00014 Triclosan [class: Phenolic compounds] 100 1.7e-139 1 256 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FCAKBLPA_00014 PHI:7915 fabI 91 4.1e-128 1 256 1.0000 1.0000 moths reduced virulence enoyl-ACP reductase reduced virulence
HHJIKCPJ_00014 PHI:7915 fabI 91 4.1e-128 1 256 1.0000 1.0000 moths reduced virulence enoyl-ACP reductase reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term