Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C108
  Reference Plasmid   CP057426.1
  Reference Plasmid Size   6676
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0144175 GJAONHBL_00001 208 4 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -16T>C None
M0144176 GJAONHBL_00001 400 4 Gut 0.57 protein_coding synonymous_variant LOW 177T>C Ile59Ile
M0144177 GJAONHBL_00005 3223 6 Gut 0.86 protein_coding upstream_gene_variant MODIFIER -2416A>G None
M0144178 GJAONHBL_00004 3738 6 Gut 0.86 protein_coding missense_variant MODERATE 1723A>G Thr575Ala
M0144179 GJAONHBL_00004 3813 6 Gut 0.86 protein_coding missense_variant MODERATE 1648G>T Gly550Trp
M0144180 GJAONHBL_00004 3975 3 Gut 0.43 protein_coding missense_variant MODERATE 1486T>C Tyr496His
M0144181 GJAONHBL_00004 4138 4 Gut 0.57 protein_coding synonymous_variant LOW 1323T>C Asn441Asn
M0144182 GJAONHBL_00004 6004 6 Gut 0.86 protein_coding upstream_gene_variant MODIFIER -544T>C None
M0144183 GJAONHBL_00004 6226 5 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -766A>G None
M0144184 GJAONHBL_00004 6251 4 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -791C>T None
M0144185 GJAONHBL_00004 3751 3 Gut 0.43 protein_coding synonymous_variant LOW 1710T>C Asp570Asp
M0144186 GJAONHBL_00004 4819 3 Gut 0.43 protein_coding synonymous_variant LOW 642A>C Gly214Gly
M0144187 GJAONHBL_00004 4828 4 Gut 0.57 protein_coding synonymous_variant LOW 633G>A Glu211Glu
M0144188 GJAONHBL_00004 4916 4 Gut 0.57 protein_coding missense_variant MODERATE 545T>A Leu182Gln
M0144189 GJAONHBL_00004 4921 4 Gut 0.57 protein_coding synonymous_variant LOW 540T>C Gly180Gly
M0144190 GJAONHBL_00004 4963 4 Gut 0.57 protein_coding synonymous_variant LOW 498G>A Ala166Ala
M0144191 GJAONHBL_00004 4986 4 Gut 0.57 protein_coding missense_variant MODERATE 475A>G Thr159Ala
M0144192 GJAONHBL_00004 5162 4 Gut 0.57 protein_coding missense_variant MODERATE 299T>C Val100Ala
M0144193 GJAONHBL_00004 5179 4 Gut 0.57 protein_coding synonymous_variant LOW 282A>T Arg94Arg
M0144194 GJAONHBL_00004 5220 4 Gut 0.57 protein_coding missense_variant MODERATE 241G>A Asp81Asn
M0144195 GJAONHBL_00004 5278 4 Gut 0.57 protein_coding synonymous_variant LOW 183A>C Ser61Ser
M0144196 GJAONHBL_00004 5291 4 Gut 0.57 protein_coding missense_variant MODERATE 170A>C Glu57Ala
M0144197 GJAONHBL_00004 5413 4 Gut 0.57 protein_coding synonymous_variant LOW 48T>C Gly16Gly
M0144198 GJAONHBL_00004 5578 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -118C>T None
M0144199 GJAONHBL_00004 5631 5 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -171T>C None
M0144200 GJAONHBL_00004 5493 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -33A>G None
M0144201 GJAONHBL_00004 5497 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -37C>G None
M0144202 GJAONHBL_00004 5498 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -38A>G None
M0144203 GJAONHBL_00004 5504 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -44T>C None
M0144204 GJAONHBL_00004 5505 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -45G>C None
M0144205 GJAONHBL_00004 5528 3 Gut 0.43 protein_coding upstream_gene_variant MODIFIER -68T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term