Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C140
  Reference Plasmid   CP088505.1
  Reference Plasmid Size   52198
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0145161 IHJLHFOF_00013 8009 3 Gut 1.00 protein_coding synonymous_variant LOW 525G>A Glu175Glu
M0145162 IHJLHFOF_00013 8012 3 Gut 1.00 protein_coding synonymous_variant LOW 522A>T Pro174Pro
M0145163 IHJLHFOF_00013 8015 3 Gut 1.00 protein_coding synonymous_variant LOW 519A>G Lys173Lys
M0145164 IHJLHFOF_00013 8033 3 Gut 1.00 protein_coding missense_variant MODERATE 501G>T Lys167Asn
M0145165 IHJLHFOF_00013 8063 3 Gut 1.00 protein_coding synonymous_variant LOW 471C>T Ser157Ser
M0145166 IHJLHFOF_00013 8080 3 Gut 1.00 protein_coding missense_variant MODERATE 454T>G Ser152Ala
M0145167 IHJLHFOF_00013 8081 3 Gut 1.00 protein_coding synonymous_variant LOW 453G>A Glu151Glu
M0145168 IHJLHFOF_00013 8092 3 Gut 1.00 protein_coding missense_variant MODERATE 442G>A Ala148Thr
M0145169 IHJLHFOF_00013 8096 3 Gut 1.00 protein_coding synonymous_variant LOW 438G>A Glu146Glu
M0145170 IHJLHFOF_00013 8102 3 Gut 1.00 protein_coding synonymous_variant LOW 432T>C Asp144Asp
M0145171 IHJLHFOF_00013 8105 3 Gut 1.00 protein_coding synonymous_variant LOW 429G>A Thr143Thr
M0145172 IHJLHFOF_00013 8108 3 Gut 1.00 protein_coding synonymous_variant LOW 426G>A Ala142Ala
M0145173 IHJLHFOF_00013 8129 3 Gut 1.00 protein_coding synonymous_variant LOW 405C>A Arg135Arg
M0145174 IHJLHFOF_00013 8274 3 Gut 1.00 protein_coding missense_variant MODERATE 260G>A Arg87His
M0145175 IHJLHFOF_00013 8449 3 Gut 1.00 protein_coding missense_variant MODERATE 85T>C Phe29Leu
M0145176 IHJLHFOF_00014 8769 3 Gut 1.00 protein_coding synonymous_variant LOW 1176T>A Ser392Ser
M0145177 IHJLHFOF_00014 8788 3 Gut 1.00 protein_coding missense_variant MODERATE 1157A>G Asn386Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
IHJLHFOF_00045 BAG78122.1|GH108 100 6.14e-138 1 186 1 0.9442
IHJLHFOF_00079 QYD25709.1|GH19 97.6 7.26e-148 1 209 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IHJLHFOF_00033 1.W.9.1.1 98.6 1.4e-297 1 512 1.0000 1.0000 1 Channels/Pores 1.W Phage Portal Protein Subclass 1.W.9 The Escherichia coli Mu Phage Portal Protein 9 (PPP9) Family