Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C151
  Reference Plasmid   CP088756.1
  Reference Plasmid Size   91717
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0145458 HIAKDPED_00091 68750 3 Gut 0.75 protein_coding synonymous_variant LOW 621G>A Thr207Thr
M0145459 HIAKDPED_00092 68934 3 Gut 0.75 protein_coding synonymous_variant LOW 126T>C Asp42Asp
M0145460 HIAKDPED_00092 68972 3 Gut 0.75 protein_coding missense_variant MODERATE 88G>A Glu30Lys
M0145461 HIAKDPED_00094 69892 3 Gut 0.75 protein_coding missense_variant MODERATE 6406G>A Ala2136Thr
M0145462 HIAKDPED_00094 69893 3 Gut 0.75 protein_coding synonymous_variant LOW 6405G>A Leu2135Leu
M0145463 HIAKDPED_00094 70393 3 Gut 0.75 protein_coding missense_variant MODERATE 5905C>A His1969Asn
M0145464 HIAKDPED_00094 70406 3 Gut 0.75 protein_coding synonymous_variant LOW 5892T>C Ala1964Ala
M0145465 HIAKDPED_00094 70418 3 Gut 0.75 protein_coding synonymous_variant LOW 5880G>A Glu1960Glu
M0145466 HIAKDPED_00094 70850 3 Gut 0.75 protein_coding synonymous_variant LOW 5448C>T Gly1816Gly
M0145467 HIAKDPED_00094 70940 3 Gut 0.75 protein_coding synonymous_variant LOW 5358T>C Gly1786Gly
M0145468 HIAKDPED_00094 70958 3 Gut 0.75 protein_coding synonymous_variant LOW 5340T>C Ile1780Ile
M0145469 HIAKDPED_00094 71009 3 Gut 0.75 protein_coding synonymous_variant LOW 5289T>C Ile1763Ile
M0145470 HIAKDPED_00094 71102 3 Gut 0.75 protein_coding synonymous_variant LOW 5196A>T Val1732Val
M0145471 HIAKDPED_00094 71300 3 Gut 0.75 protein_coding synonymous_variant LOW 4998T>G Gly1666Gly
M0145472 HIAKDPED_00094 71324 3 Gut 0.75 protein_coding synonymous_variant LOW 4974T>C Asn1658Asn
M0145473 HIAKDPED_00094 72199 3 Gut 0.75 protein_coding missense_variant MODERATE 4099T>C Ser1367Pro
M0145474 HIAKDPED_00094 72221 3 Gut 0.75 protein_coding synonymous_variant LOW 4077T>C Ile1359Ile
M0145475 HIAKDPED_00094 72239 3 Gut 0.75 protein_coding synonymous_variant LOW 4059C>G Pro1353Pro
M0145476 HIAKDPED_00094 72282 3 Gut 0.75 protein_coding missense_variant MODERATE 4016A>G Lys1339Arg
M0145477 HIAKDPED_00094 72323 3 Gut 0.75 protein_coding synonymous_variant LOW 3975A>T Val1325Val
M0145478 HIAKDPED_00094 72383 3 Gut 0.75 protein_coding synonymous_variant LOW 3915G>A Ser1305Ser
M0145479 HIAKDPED_00094 72487 3 Gut 0.75 protein_coding synonymous_variant LOW 3811A>C Arg1271Arg
M0145480 HIAKDPED_00094 72617 3 Gut 0.75 protein_coding synonymous_variant LOW 3681C>A Ala1227Ala
M0145481 HIAKDPED_00094 72671 3 Gut 0.75 protein_coding synonymous_variant LOW 3627G>T Thr1209Thr
M0145482 HIAKDPED_00094 72875 3 Gut 0.75 protein_coding synonymous_variant LOW 3423T>A Val1141Val
M0145483 HIAKDPED_00094 72892 3 Gut 0.75 protein_coding missense_variant MODERATE 3406G>A Gly1136Ser
M0145484 HIAKDPED_00094 72929 3 Gut 0.75 protein_coding synonymous_variant LOW 3369G>T Val1123Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
HIAKDPED_00006 AZH90090.1|GH23 100 0 1 1130 1 1
HIAKDPED_00094 AYL89119.1|GH24 97 0 1753 2255 0.2231 0.9031
HIAKDPED_00097 AJS09995.1|GH24 100 4.67e-139 1 185 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
HIAKDPED_00107 1.E.4.1.1 100 1.3e-54 1 109 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.4 The LydA Holin (LydA Holin) Family