Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C154
  Reference Plasmid   CP088797.1
  Reference Plasmid Size   79036
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0145588 ADKCKPMO_00035 31340 3 Gut 1.00 protein_coding missense_variant MODERATE 269G>T Arg90Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
ADKCKPMO_00070 VFG034574 Dispersin 96.6 3.7e-61 1 116 1.0 1 Others dispersin experiment
ADKCKPMO_00076 VFG035902 Dispersin 97.3 1.8e-194 6 381 0.9869 1 Others permease AatP experiment
ADKCKPMO_00077 VFG035909 Dispersin 96.8 8.6e-222 1 412 1.0 1 Others outer membrane protein AatA experiment
ADKCKPMO_00078 VFG035916 Dispersin 97.2 2.7e-110 1 212 1.0 0.7766 Others AatB experiment
ADKCKPMO_00079 VFG035923 Dispersin 98.1 1e-109 1 209 1.0 1 Others ATP-binding protein AatC experiment
ADKCKPMO_00080 VFG035929 Dispersin 98 5.6e-226 1 403 1.0 0.9975 Others AatD experiment
ADKCKPMO_00051 VFG000850 AAFs 100 4.6e-145 1 252 1.0 1 Adherence chaperone prediction
ADKCKPMO_00054 VFG034587 AAFs 97.9 4.8e-78 1 145 1.0 1 Adherence invasin protein prediction
ADKCKPMO_00055 VFG000847 AAFs 72.7 1.2e-64 1 172 1.0 1.0058 Adherence fimbrial major subunit prediction
ADKCKPMO_00069 VFG036086 AggR 99.6 1.3e-142 1 265 1.0 1 Regulation aggregative adherence transcriptional regulator AggR prediction
ADKCKPMO_00070 VFG034574 Dispersin 96.6 2.7e-60 1 116 1.0 1 Others dispersin prediction
ADKCKPMO_00076 VFG035901 Dispersin 100 6.4e-199 6 381 0.9869 1 Others permease AatP prediction
ADKCKPMO_00077 VFG035908 Dispersin 99.8 2.7e-227 1 412 1.0 1 Others outer membrane protein AatA prediction
ADKCKPMO_00078 VFG035915 Dispersin 100 1.1e-112 1 212 1.0 0.7766 Others AatB prediction
ADKCKPMO_00079 VFG035919 Dispersin 99.5 4e-110 1 209 1.0 1 Others ATP-binding protein AatC prediction
ADKCKPMO_00080 VFG035928 Dispersin 100 9.7e-230 1 403 1.0 1 Others AatD prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
ADKCKPMO_00015 ARO:3004623 100 4.76e-213 1 286 1.0000 1.0000 aminoglycoside antibiotic AAC(3) antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
ADKCKPMO_00028 PHI:11470 STM14_3563 88 1.7e-33 5 87 0.9432 0.9121 rodents salmonellosis putative transcriptional regulator reduced virulence
ADKCKPMO_00069 PHI:9507 aggR 99.6 4.6e-143 1 265 1.0000 1.0000 moths diarrhea transcriptional activator reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term