Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C155
  Reference Plasmid   CP088810.1
  Reference Plasmid Size   81175
  Reference Plasmid GC Content   0.49
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0145589 ILFIFMGP_00057 34000 3 Gut 0.30 protein_coding missense_variant MODERATE 768A>C Arg256Ser
M0145590 ILFIFMGP_00087 64672 5 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -1888T>A None
M0145591 ILFIFMGP_00089 64882 5 Gut 0.50 protein_coding synonymous_variant LOW 16C>T Leu6Leu
M0145592 ILFIFMGP_00090 66902 5 Gut 0.50 protein_coding synonymous_variant LOW 870G>T Gly290Gly
M0145593 ILFIFMGP_00091 67290 4 Gut 0.40 protein_coding missense_variant MODERATE 317A>T Tyr106Phe
M0145594 ILFIFMGP_00091 67367 5 Gut 0.50 protein_coding synonymous_variant LOW 240A>G Ala80Ala
M0145595 ILFIFMGP_00091 67382 5 Gut 0.50 protein_coding synonymous_variant LOW 225A>G Thr75Thr
M0145596 ILFIFMGP_00091 67406 5 Gut 0.50 protein_coding synonymous_variant LOW 201T>C Leu67Leu
M0145597 ILFIFMGP_00091 67421 5 Gut 0.50 protein_coding missense_variant MODERATE 186T>G Asp62Glu
M0145598 ILFIFMGP_00092 67783 4 Gut 0.40 protein_coding synonymous_variant LOW 3222C>T His1074His
M0145599 ILFIFMGP_00092 67813 4 Gut 0.40 protein_coding synonymous_variant LOW 3192T>G Ala1064Ala
M0145600 ILFIFMGP_00092 68190 5 Gut 0.50 protein_coding missense_variant MODERATE 2815A>G Thr939Ala
M0145601 ILFIFMGP_00092 68596 4 Gut 0.40 protein_coding synonymous_variant LOW 2409A>C Ser803Ser
M0145602 ILFIFMGP_00092 68653 4 Gut 0.40 protein_coding synonymous_variant LOW 2352G>A Leu784Leu
M0145603 ILFIFMGP_00092 68659 4 Gut 0.40 protein_coding synonymous_variant LOW 2346C>T Asn782Asn
M0145604 ILFIFMGP_00092 68677 4 Gut 0.40 protein_coding synonymous_variant LOW 2328T>C Ser776Ser
M0145605 ILFIFMGP_00092 68746 4 Gut 0.40 protein_coding synonymous_variant LOW 2259A>C Gly753Gly
M0145606 ILFIFMGP_00092 68923 4 Gut 0.40 protein_coding synonymous_variant LOW 2082C>T Ser694Ser
M0145607 ILFIFMGP_00092 69072 4 Gut 0.40 protein_coding missense_variant MODERATE 1933C>A Leu645Ile
M0145608 ILFIFMGP_00092 69193 4 Gut 0.40 protein_coding synonymous_variant LOW 1812C>A Gly604Gly
M0145609 ILFIFMGP_00092 69285 4 Gut 0.40 protein_coding missense_variant MODERATE 1720C>A Pro574Thr
M0145610 ILFIFMGP_00092 69371 4 Gut 0.40 protein_coding missense_variant MODERATE 1634T>C Ile545Thr
M0145611 ILFIFMGP_00092 69490 4 Gut 0.40 protein_coding synonymous_variant LOW 1515T>C Asn505Asn
M0145612 ILFIFMGP_00092 69550 4 Gut 0.40 protein_coding synonymous_variant LOW 1455A>G Thr485Thr
M0145613 ILFIFMGP_00092 69553 4 Gut 0.40 protein_coding synonymous_variant LOW 1452G>A Ala484Ala
M0145614 ILFIFMGP_00092 69556 4 Gut 0.40 protein_coding synonymous_variant LOW 1449C>G Ala483Ala
M0145615 ILFIFMGP_00092 69559 4 Gut 0.40 protein_coding synonymous_variant LOW 1446T>G Leu482Leu
M0145616 ILFIFMGP_00092 69571 4 Gut 0.40 protein_coding synonymous_variant LOW 1434A>G Thr478Thr
M0145617 ILFIFMGP_00092 69574 4 Gut 0.40 protein_coding synonymous_variant LOW 1431C>T Ser477Ser
M0145618 ILFIFMGP_00092 69586 4 Gut 0.40 protein_coding synonymous_variant LOW 1419C>T Ser473Ser
M0145619 ILFIFMGP_00092 69592 4 Gut 0.40 protein_coding synonymous_variant LOW 1413A>C Leu471Leu
M0145620 ILFIFMGP_00092 69598 4 Gut 0.40 protein_coding synonymous_variant LOW 1407C>A Val469Val
M0145621 ILFIFMGP_00092 69619 4 Gut 0.40 protein_coding synonymous_variant LOW 1386C>T Ser462Ser
M0145622 ILFIFMGP_00092 69622 4 Gut 0.40 protein_coding synonymous_variant LOW 1383G>A Ala461Ala
M0145623 ILFIFMGP_00092 69679 4 Gut 0.40 protein_coding synonymous_variant LOW 1326T>C Ala442Ala
M0145624 ILFIFMGP_00092 69835 4 Gut 0.40 protein_coding synonymous_variant LOW 1170C>A Ala390Ala
M0145625 ILFIFMGP_00092 69892 4 Gut 0.40 protein_coding synonymous_variant LOW 1113T>C Arg371Arg
M0145626 ILFIFMGP_00092 69894 4 Gut 0.40 protein_coding missense_variant MODERATE 1111C>A Arg371Ser
M0145627 ILFIFMGP_00093 71117 4 Gut 0.40 protein_coding synonymous_variant LOW 552C>T Gly184Gly
M0145628 ILFIFMGP_00087 64644 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1860G>A None
M0145629 ILFIFMGP_00087 64677 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1893A>C None
M0145630 ILFIFMGP_00087 64678 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1894T>C None
M0145631 ILFIFMGP_00087 64679 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1895A>G None
M0145632 ILFIFMGP_00087 64695 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1911G>C None
M0145633 ILFIFMGP_00087 64706 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1922C>T None
M0145634 ILFIFMGP_00087 64757 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1973A>G None
M0145635 ILFIFMGP_00087 64761 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1977T>A None
M0145636 ILFIFMGP_00087 64766 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1982A>C None
M0145637 ILFIFMGP_00087 64780 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1996G>A None
M0145638 ILFIFMGP_00087 64781 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -1997A>C None
M0145639 ILFIFMGP_00089 64992 3 Gut 0.30 protein_coding synonymous_variant LOW 126T>A Ile42Ile
M0145640 ILFIFMGP_00089 65190 3 Gut 0.30 protein_coding synonymous_variant LOW 324T>G Val108Val
M0145641 ILFIFMGP_00089 65310 3 Gut 0.30 protein_coding synonymous_variant LOW 444T>C Gly148Gly
M0145642 ILFIFMGP_00089 65313 3 Gut 0.30 protein_coding synonymous_variant LOW 447A>G Thr149Thr
M0145643 ILFIFMGP_00089 65986 3 Gut 0.30 protein_coding synonymous_variant LOW 1120A>C Arg374Arg
M0145644 ILFIFMGP_00090 66581 3 Gut 0.30 protein_coding synonymous_variant LOW 549G>A Leu183Leu
M0145645 ILFIFMGP_00090 66605 3 Gut 0.30 protein_coding synonymous_variant LOW 573A>G Arg191Arg
M0145646 ILFIFMGP_00090 66714 3 Gut 0.30 protein_coding missense_variant MODERATE 682A>G Ile228Val
M0145647 ILFIFMGP_00090 66765 3 Gut 0.30 protein_coding missense_variant MODERATE 733A>G Thr245Ala
M0145648 ILFIFMGP_00090 66770 3 Gut 0.30 protein_coding synonymous_variant LOW 738A>T Ile246Ile
M0145649 ILFIFMGP_00090 66958 3 Gut 0.30 protein_coding missense_variant MODERATE 926A>G Lys309Arg
M0145650 ILFIFMGP_00087 67002 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -4218A>G None
M0145651 ILFIFMGP_00091 67238 3 Gut 0.30 protein_coding synonymous_variant LOW 369A>G Leu123Leu
M0145652 ILFIFMGP_00091 67253 3 Gut 0.30 protein_coding synonymous_variant LOW 354A>G Ala118Ala
M0145653 ILFIFMGP_00091 67255 3 Gut 0.30 protein_coding missense_variant MODERATE 352G>A Ala118Thr
M0145654 ILFIFMGP_00091 67259 3 Gut 0.30 protein_coding synonymous_variant LOW 348A>G Lys116Lys
M0145655 ILFIFMGP_00091 67292 3 Gut 0.30 protein_coding synonymous_variant LOW 315A>G Glu105Glu
M0145656 ILFIFMGP_00091 67298 3 Gut 0.30 protein_coding missense_variant MODERATE 309A>T Glu103Asp
M0145657 ILFIFMGP_00091 67307 3 Gut 0.30 protein_coding synonymous_variant LOW 300A>G Leu100Leu
M0145658 ILFIFMGP_00091 67316 3 Gut 0.30 protein_coding synonymous_variant LOW 291T>C Val97Val
M0145659 ILFIFMGP_00091 67331 3 Gut 0.30 protein_coding synonymous_variant LOW 276G>A Pro92Pro
M0145660 ILFIFMGP_00091 67334 3 Gut 0.30 protein_coding synonymous_variant LOW 273T>C Gly91Gly
M0145661 ILFIFMGP_00091 67337 3 Gut 0.30 protein_coding synonymous_variant LOW 270C>T Leu90Leu
M0145662 ILFIFMGP_00091 67361 4 Gut 0.40 protein_coding synonymous_variant LOW 246G>C Gly82Gly
M0145663 ILFIFMGP_00091 67364 4 Gut 0.40 protein_coding synonymous_variant LOW 243A>C Ser81Ser
M0145664 ILFIFMGP_00091 67379 3 Gut 0.30 protein_coding synonymous_variant LOW 228T>C Val76Val
M0145665 ILFIFMGP_00091 67445 3 Gut 0.30 protein_coding synonymous_variant LOW 162C>T Phe54Phe
M0145666 ILFIFMGP_00091 67466 3 Gut 0.30 protein_coding synonymous_variant LOW 141G>A Pro47Pro
M0145667 ILFIFMGP_00091 67514 4 Gut 0.40 protein_coding synonymous_variant LOW 93C>T Tyr31Tyr
M0145668 ILFIFMGP_00092 68173 3 Gut 0.30 protein_coding synonymous_variant LOW 2832C>T Gly944Gly
M0145669 ILFIFMGP_00092 68339 3 Gut 0.30 protein_coding missense_variant MODERATE 2666G>A Gly889Asp
M0145670 ILFIFMGP_00092 68356 3 Gut 0.30 protein_coding synonymous_variant LOW 2649C>T Gly883Gly
M0145671 ILFIFMGP_00092 68359 3 Gut 0.30 protein_coding synonymous_variant LOW 2646T>C Asp882Asp
M0145672 ILFIFMGP_00092 68368 3 Gut 0.30 protein_coding synonymous_variant LOW 2637C>T Ser879Ser
M0145673 ILFIFMGP_00092 68386 3 Gut 0.30 protein_coding synonymous_variant LOW 2619A>T Gly873Gly
M0145674 ILFIFMGP_00092 68485 3 Gut 0.30 protein_coding synonymous_variant LOW 2520C>T Tyr840Tyr
M0145675 ILFIFMGP_00092 68614 3 Gut 0.30 protein_coding synonymous_variant LOW 2391G>T Gly797Gly
M0145676 ILFIFMGP_00092 70591 3 Gut 0.30 protein_coding synonymous_variant LOW 414C>A Ala138Ala
M0145677 ILFIFMGP_00093 71348 3 Gut 0.30 protein_coding synonymous_variant LOW 321G>A Val107Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
ILFIFMGP_00059 AML08192.1|GH24 100 7.66e-117 1 165 1 1
ILFIFMGP_00083 BCA44326.1|GH24 83.1 0 3 1164 0.9974 0.944
ILFIFMGP_00094 BCA44326.1|GH24 83.1 0 3 1164 0.9974 0.944





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
ILFIFMGP_00060 1.M.1.1.4 90.3 6e-68 1 144 0.9931 0.9931 1 Channels/Pores 1.M Membrane Fusion-mediating Spanins 1.M.1 The Rz/Rz1 Spanin1 (Rz(1)) Family
ILFIFMGP_00067 1.W.5.1.1 99.6 3.39999999997601e-313 1 533 1.0000 1.0000 1 Channels/Pores 1.W Phage Portal Protein Subclass 1.W.5 The (Lambda) Phage Portal Protein 5 (PPP5) Family
ILFIFMGP_00083 1.E.1.1.7 99.3 0 488 1165 0.5820 0.9417 1 Channels/Pores 1.E Holins 1.E.1 The P21 Holin S (P21 Holin) Family
ILFIFMGP_00084 1.B.6.2.20 95 2.4e-107 1 199 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.6 The OmpA-OmpF Porin (OOP) Family
ILFIFMGP_00093 1.B.6.2.20 95 2.4e-107 1 199 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.6 The OmpA-OmpF Porin (OOP) Family
ILFIFMGP_00094 1.E.1.1.7 99.3 0 488 1165 0.5820 0.9417 1 Channels/Pores 1.E Holins 1.E.1 The P21 Holin S (P21 Holin) Family