Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C183
  Reference Plasmid   CP103152.1
  Reference Plasmid Size   8748
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0146468 AADMCHHP_00009 4509 11 Gut 0.39 protein_coding upstream_gene_variant MODIFIER -21G>T None
M0146469 AADMCHHP_00010 5432 11 Gut 0.39 protein_coding upstream_gene_variant MODIFIER -70G>A None
M0146470 AADMCHHP_00010 5464 8 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -102G>A None
M0146471 AADMCHHP_00010 5511 15 Gut 0.54 protein_coding upstream_gene_variant MODIFIER -149C>T None
M0146472 AADMCHHP_00009 4475 7 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -55C>A None
M0146473 AADMCHHP_00004 936 4 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -199C>T None
M0146474 AADMCHHP_00004 981 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -154T>C None
M0146475 AADMCHHP_00004 1052 9 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -83T>G None
M0146476 AADMCHHP_00004 1905 4 Gut 0.14 protein_coding missense_variant MODERATE 771T>G His257Gln
M0146477 AADMCHHP_00005 2100 10 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -111C>A None
M0146478 AADMCHHP_00006 2908 7 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -249A>G None
M0146479 AADMCHHP_00007 3550 7 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -93T>A None
M0146480 AADMCHHP_00007 3565 7 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -78G>A None
M0146481 AADMCHHP_00007 3761 5 Gut 0.18 protein_coding missense_variant MODERATE 119C>T Ala40Val
M0146482 AADMCHHP_00009 4783 7 Gut 0.25 protein_coding missense_variant MODERATE 254C>T Ala85Val
M0146483 AADMCHHP_00001 61 3 Gut 0.11 protein_coding missense_variant MODERATE 61G>A Asp21Asn
M0146484 AADMCHHP_00001 99 3 Gut 0.11 protein_coding synonymous_variant LOW 99C>T Asn33Asn
M0146485 AADMCHHP_00002 638 4 Gut 0.14 protein_coding synonymous_variant LOW 285A>C Ile95Ile
M0146486 AADMCHHP_00011 5950 4 Gut 0.14 protein_coding synonymous_variant LOW 900T>C Ile300Ile
M0146487 AADMCHHP_00011 6007 4 Gut 0.14 protein_coding synonymous_variant LOW 843T>A Gly281Gly
M0146488 AADMCHHP_00011 6010 4 Gut 0.14 protein_coding synonymous_variant LOW 840A>G Arg280Arg
M0146489 AADMCHHP_00011 6069 7 Gut 0.25 protein_coding synonymous_variant LOW 781T>C Leu261Leu
M0146490 AADMCHHP_00011 6523 3 Gut 0.11 protein_coding synonymous_variant LOW 327T>C Phe109Phe
M0146491 AADMCHHP_00011 6772 3 Gut 0.11 protein_coding missense_variant MODERATE 78T>G Ile26Met
M0146492 AADMCHHP_00012 7497 3 Gut 0.11 protein_coding synonymous_variant LOW 120G>A Ala40Ala
M0146493 AADMCHHP_00010 8299 4 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -2937A>T None
M0146494 AADMCHHP_00014 8467 8 Gut 0.29 protein_coding synonymous_variant LOW 213A>G Gly71Gly
M0146495 AADMCHHP_00014 8658 3 Gut 0.11 protein_coding missense_variant MODERATE 22G>T Gly8Trp
M0146496 AADMCHHP_00014 8677 3 Gut 0.11 protein_coding start_lost HIGH 3G>A Met1?
M0146497 AADMCHHP_00010 8688 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -3326G>A None
M0146498 AADMCHHP_00010 8690 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -3328G>C None
M0146499 AADMCHHP_00005 2789 3 Gut 0.11 protein_coding synonymous_variant LOW 579C>T Ser193Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term